Immunodeficiencies affecting cellular and humoral immunity

Zahra Chavoshzadeh; Sepideh Darougar; Tooba Momen; Hossein Esmaeilzadeh; Hassan Abolhassani; Taher Cheraghi; Mirjam van der Burg; Menno van Zelm

doi:10.1016/B978-0-12-821028-4.00010-5

Immunodeficiencies affecting cellular and humoral immunity

Zahra Chavoshzadeh, Sepideh Darougar, Tooba Momen, Hossein Esmaeilzadeh, Hassan Abolhassani, Taher Cheraghi, Mirjam van der Burg, Menno van Zelm

Research output: Chapter/Conference proceeding › Chapter › Academic

3 Citations (Scopus)

Abstract

Combined immunodeficiencies (CIDs) are the result of defective development or function of T cells. As the most severe form of primary immunodeficiency disorders (PID), CIDs are characterized by a susceptibility to infection, particularly from opportunistic organisms, which leads to severe morbidity and mortality. A subpopulation of patients has additional syndromic features caused by the function of the affected gene beyond the immune system. In this chapter, we will focus on nonsyndromic CIDs.

Original language	English
Title of host publication	Inborn Errors of Immunity
Subtitle of host publication	A Practical Guide
Publisher	Elsevier
Chapter	2
Pages	9-39
Number of pages	31
ISBN (Electronic)	9780128210284
ISBN (Print)	9780128231890
DOIs	https://doi.org/10.1016/B978-0-12-821028-4.00010-5
Publication status	Published - 1 Jan 2021
Externally published	Yes

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© 2021 Elsevier Inc. All rights reserved.

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10.1016/B978-0-12-821028-4.00010-5

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AU - Chavoshzadeh, Zahra

AU - Darougar, Sepideh

AU - Momen, Tooba

AU - Esmaeilzadeh, Hossein

AU - Abolhassani, Hassan

AU - Cheraghi, Taher

AU - van der Burg, Mirjam

AU - van Zelm, Menno

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AB - Combined immunodeficiencies (CIDs) are the result of defective development or function of T cells. As the most severe form of primary immunodeficiency disorders (PID), CIDs are characterized by a susceptibility to infection, particularly from opportunistic organisms, which leads to severe morbidity and mortality. A subpopulation of patients has additional syndromic features caused by the function of the affected gene beyond the immune system. In this chapter, we will focus on nonsyndromic CIDs.

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SN - 9780128231890

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BT - Inborn Errors of Immunity

PB - Elsevier

ER -

Immunodeficiencies affecting cellular and humoral immunity

Abstract

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