Immunodeficiencies affecting cellular and humoral immunity

Zahra Chavoshzadeh; Sepideh Darougar; Tooba Momen; Hossein Esmaeilzadeh; Hassan Abolhassani; Taher Cheraghi; Mirjam van der Burg; Menno van Zelm

doi:10.1016/B978-0-12-821028-4.00010-5

Immunodeficiencies affecting cellular and humoral immunity

Zahra Chavoshzadeh
, Sepideh Darougar
, Tooba Momen
, Hossein Esmaeilzadeh
, Hassan Abolhassani
, Taher Cheraghi
, Mirjam van der Burg
, Menno van Zelm

Shahid Beheshti University of Medical Sciences
Islamic Azad University
Isfahan University of Medical Sciences
Shiraz University of Medical Sciences
Karolinska Institutet
Tehran University of Medical Sciences
Guilan University of Medical Sciences
Leiden University Medical Centre
Monash University

Research output: Chapter/Conference proceeding › Chapter › Academic

4 Citations (Scopus)

Abstract

Combined immunodeficiencies (CIDs) are the result of defective development or function of T cells. As the most severe form of primary immunodeficiency disorders (PID), CIDs are characterized by a susceptibility to infection, particularly from opportunistic organisms, which leads to severe morbidity and mortality. A subpopulation of patients has additional syndromic features caused by the function of the affected gene beyond the immune system. In this chapter, we will focus on nonsyndromic CIDs.

Original language	English
Title of host publication	Inborn Errors of Immunity
Subtitle of host publication	A Practical Guide
Publisher	Elsevier
Chapter	2
Pages	9-39
Number of pages	31
ISBN (Electronic)	9780128210284
ISBN (Print)	9780128231890
DOIs	https://doi.org/10.1016/B978-0-12-821028-4.00010-5
Publication status	Published - 1 Jan 2021
Externally published	Yes

Bibliographical note

Publisher Copyright:
© 2021 Elsevier Inc. All rights reserved.

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10.1016/B978-0-12-821028-4.00010-5

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T1 - Immunodeficiencies affecting cellular and humoral immunity

AU - Chavoshzadeh, Zahra

AU - Darougar, Sepideh

AU - Momen, Tooba

AU - Esmaeilzadeh, Hossein

AU - Abolhassani, Hassan

AU - Cheraghi, Taher

AU - van der Burg, Mirjam

AU - van Zelm, Menno

PY - 2021/1/1

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AB - Combined immunodeficiencies (CIDs) are the result of defective development or function of T cells. As the most severe form of primary immunodeficiency disorders (PID), CIDs are characterized by a susceptibility to infection, particularly from opportunistic organisms, which leads to severe morbidity and mortality. A subpopulation of patients has additional syndromic features caused by the function of the affected gene beyond the immune system. In this chapter, we will focus on nonsyndromic CIDs.

UR - https://www.scopus.com/pages/publications/85137457980

U2 - 10.1016/B978-0-12-821028-4.00010-5

DO - 10.1016/B978-0-12-821028-4.00010-5

M3 - Chapter

AN - SCOPUS:85137457980

SN - 9780128231890

SP - 9

EP - 39

BT - Inborn Errors of Immunity

PB - Elsevier

ER -

Immunodeficiencies affecting cellular and humoral immunity

Abstract

Bibliographical note

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