TY - JOUR
T1 - Implementation of flow cytometry in the diagnostic work-up of myelodysplastic syndromes in a multicenter approach
T2 - Report from the Dutch Working Party on Flow Cytometry in MDS
AU - Westers, Theresia M.
AU - van der Velden, Vincent H.J.
AU - Alhan, Canan
AU - Bekkema, Roelof
AU - Bijkerk, André
AU - Brooimans, Rik A.
AU - Cali, Claudia
AU - Dräger, Angelika M.
AU - de Haas, Valerie
AU - Homburg, Christa
AU - de Jong, Anja
AU - Kuiper-Kramer, P. Ellen A.
AU - Leenders, Marije
AU - Lommerse, Ingrid
AU - te Marvelde, Jeroen G.
AU - van der Molen-Sinke, Joke K.
AU - Moshaver, Bijan
AU - Mulder, Andre B.
AU - Preijers, Frank W.M.B.
AU - Schindhelm, Roger K.
AU - van der Sluijs, Alita
AU - van Wering, Elisabeth R.
AU - Westra, August H.
AU - van de Loosdrecht, Arjan A.
PY - 2012/4
Y1 - 2012/4
N2 - Flow cytometry (FC) is recognized as an important tool in the diagnosis of myelodysplastic syndromes (MDS) especially when standard criteria fail. A working group within the Dutch Society of Cytometry aimed to implement FC in the diagnostic work-up of MDS. Hereto, guidelines for data acquisition, analysis and interpretation were formulated. Based on discussions on analyses of list mode data files and fresh MDS bone marrow samples and recent literature, the guidelines were modified. Over the years (2005-2011), the concordance between the participating centers increased indicating that the proposed guidelines contributed to a more objective, standardized FC analysis, thereby ratifying the implementation of FC in MDS.
AB - Flow cytometry (FC) is recognized as an important tool in the diagnosis of myelodysplastic syndromes (MDS) especially when standard criteria fail. A working group within the Dutch Society of Cytometry aimed to implement FC in the diagnostic work-up of MDS. Hereto, guidelines for data acquisition, analysis and interpretation were formulated. Based on discussions on analyses of list mode data files and fresh MDS bone marrow samples and recent literature, the guidelines were modified. Over the years (2005-2011), the concordance between the participating centers increased indicating that the proposed guidelines contributed to a more objective, standardized FC analysis, thereby ratifying the implementation of FC in MDS.
UR - https://www.scopus.com/pages/publications/84857233462
U2 - 10.1016/j.leukres.2011.09.015
DO - 10.1016/j.leukres.2011.09.015
M3 - Article
C2 - 21982641
AN - SCOPUS:84857233462
SN - 0145-2126
VL - 36
SP - 422
EP - 430
JO - Leukemia Research
JF - Leukemia Research
IS - 4
ER -
