Implementation of the kidney team at home intervention: Evaluating generalizability, implementation process, and effects

S. Redeker, E. K. Massey, the Kidney Team at Home consortium, Charlotte Boonstra, Jan J. van Busschbach, Reinier Timman, Harald F.H. Brulez, Daan A.A.M.J. Hollander, L. B. Hilbrands, Frederike Bemelman, Stefan P. Berger, Jacqueline van de Wetering, René M.A. van den Dorpel, Margriet Dekker-Jansen, Willem Weimar, Sohal Y. Ismail

Research output: Contribution to journalArticleAcademicpeer-review

4 Citations (Scopus)
18 Downloads (Pure)


Research has shown that a home-based educational intervention for patients with chronic kidney disease results in better knowledge and communication, and more living donor kidney transplantations (LDKT). Implementation research in the field of renal care is almost nonexistent. The aims of this study were (1) to demonstrate generalizability, (2) evaluate the implementation process, and (3) to assess the relationship of intervention effects on LDKT-activity. Eight hospitals participated in the project. Patients eligible for all kidney replacement therapies (KRT) were invited to participate. Effect outcomes were KRT-knowledge and KRT-communication, and treatment choice. Feasibility, fidelity, and intervention costs were assessed as part of the process evaluation. Three hundred and thirty-two patients completed the intervention. There was a significant increase in KRT-knowledge and KRT-communication among participants. One hundred and twenty-nine out of 332 patients (39%) had LDKT-activity, which was in line with the results of the clinical trials. Protocol adherence, knowledge, and age were correlated with LDKT-activity. This unique implementation study shows that the results in practice are comparable to the previous trials, and show that the intervention can be implemented, while maintaining quality. Results from the project resulted in the uptake of the intervention in standard care. We urge other countries to investigate the uptake of the intervention.

Original languageEnglish
Pages (from-to)2317-2328
Number of pages12
JournalTransplant International
Issue number11
Early online date14 Aug 2021
Publication statusPublished - Nov 2021

Bibliographical note

Funding Information:
The implementation project was supported by Zorgverzekeraars Nederland.

Publisher Copyright:
© 2021 The Authors. Transplant International published by John Wiley & Sons Ltd on behalf of Steunstichting ESOT


Dive into the research topics of 'Implementation of the kidney team at home intervention: Evaluating generalizability, implementation process, and effects'. Together they form a unique fingerprint.

Cite this