In-depth assessment of health-related quality of life after in-hospital cardiac arrest

M. Schluep*, H. Endeman, B. Y. Gravesteijn, C. Kuijs, M. J. Blans, B. van den Bogaard, A. W.M.M.Koopman Van Gemert, C. J. Hukshorn, B. J.M. van der Meer, A. H.M. Knook, T. van Melsen, R. Peters, K. S. Simons, G. Spijkers, J. W. Vermeijden, E. J. Wils, R. J. Stolker, S. E. Hoeks

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Introduction: Evidence on physical and psychological well-being of in-hospital cardiac arrest (IHCA) survivors is scarce. The aim of this study is to describe long-term health-related quality of life (HRQoL), functional independence and psychological distress 3 and 12 months post-IHCA. Methods: A multicenter prospective cohort study in 25 hospitals between January 2017 – May 2018. Adult IHCA survivors were included. HRQoL (EQ-5D-5L, SF-12), psychological distress (HADS, CSI) and functional independence (mRS) were assessed at 3 and 12 months post-IHCA. Results: At 3-month follow-up 136 of 212 survivors responded to the questionnaire and at 12 months 110 of 198 responded. The median (IQR) EQ-utility Index score was 0.77 (0.65–0.87) at 3 months and 0.81 (0.70–0.91) at 12 months. At 3 months, patients reported a median SF-12 (IQR) physical component scale (PCS) of 38.9 (32.8–46.5) and mental component scale (MCS) of 43.5 (34.0–39.7) and at 12 months a PCS of 43.1 (34.6–52.3) and MCS 46.9 (38.5–54.5). Discussion: Using various tools most IHCA survivors report an acceptable HRQoL and a substantial part experiences lower HRQoL compared to population norms. Our data suggest that younger (male) patients and those with poor functional status prior to admission are at highest risk of impaired HRQoL.

Original languageEnglish
Pages (from-to)22-30
Number of pages9
JournalJournal of Critical Care
Publication statusPublished - 2022

Bibliographical note

Funding Information:
This study was funded by Departmental Funds of the Participating Hospitals . Licensing of the SF-12 software (€800) was funded by the ESA Air Liquide unrestricted research grant 2017, as well as printing and postage costs (approx. €300).

Publisher Copyright:
© 2021 The Authors


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