In-depth assessment of health-related quality of life after in-hospital cardiac arrest

M. Schluep; H. Endeman; B. Y. Gravesteijn; C. Kuijs; M. J. Blans; B. van den Bogaard; A. W.M.M.Koopman Van Gemert; C. J. Hukshorn; B. J.M. van der Meer; A. H.M. Knook; T. van Melsen; R. Peters; K. S. Simons; G. Spijkers; J. W. Vermeijden; E. J. Wils; R. J. Stolker; S. E. Hoeks

doi:10.1016/j.jcrc.2021.11.008

In-depth assessment of health-related quality of life after in-hospital cardiac arrest

M. Schluep^*
, H. Endeman
, B. Y. Gravesteijn
, C. Kuijs
, M. J. Blans
, B. van den Bogaard
, A. W.M.M.Koopman Van Gemert
, C. J. Hukshorn
, B. J.M. van der Meer
, A. H.M. Knook
, T. van Melsen
, R. Peters
, K. S. Simons
, G. Spijkers
, J. W. Vermeijden
, E. J. Wils
, R. J. Stolker
, S. E. Hoeks

^*Corresponding author for this work

Maasstad Hospital
Rijnstate Hospital
Onze Lieve Vrouwe Gasthuis
Albert Schweitzer Ziekenhuis
Isala Clinics
Haaglanden Medisch Centrum
Jeroen Bosch Ziekenhuis
Bravis Hospital/ZorgSaam Hospital Zeeuws-Vlaanderen
Medisch Spectrum Twente
Tergooi Ziekenhuis
Reinier de Graaf Groep
Franciscus Gasthuis & Vlietland

Research output: Contribution to journal › Article › Academic › peer-review

8 Citations (Scopus)

218 Downloads (Pure)

Abstract

Introduction: Evidence on physical and psychological well-being of in-hospital cardiac arrest (IHCA) survivors is scarce. The aim of this study is to describe long-term health-related quality of life (HRQoL), functional independence and psychological distress 3 and 12 months post-IHCA. Methods: A multicenter prospective cohort study in 25 hospitals between January 2017 – May 2018. Adult IHCA survivors were included. HRQoL (EQ-5D-5L, SF-12), psychological distress (HADS, CSI) and functional independence (mRS) were assessed at 3 and 12 months post-IHCA. Results: At 3-month follow-up 136 of 212 survivors responded to the questionnaire and at 12 months 110 of 198 responded. The median (IQR) EQ-utility Index score was 0.77 (0.65–0.87) at 3 months and 0.81 (0.70–0.91) at 12 months. At 3 months, patients reported a median SF-12 (IQR) physical component scale (PCS) of 38.9 (32.8–46.5) and mental component scale (MCS) of 43.5 (34.0–39.7) and at 12 months a PCS of 43.1 (34.6–52.3) and MCS 46.9 (38.5–54.5). Discussion: Using various tools most IHCA survivors report an acceptable HRQoL and a substantial part experiences lower HRQoL compared to population norms. Our data suggest that younger (male) patients and those with poor functional status prior to admission are at highest risk of impaired HRQoL.

Original language	English
Pages (from-to)	22-30
Number of pages	9
Journal	Journal of Critical Care
Volume	68
DOIs	https://doi.org/10.1016/j.jcrc.2021.11.008
Publication status	Published - 2022

Bibliographical note

Funding Information:
This study was funded by Departmental Funds of the Participating Hospitals . Licensing of the SF-12 software (€800) was funded by the ESA Air Liquide unrestricted research grant 2017, as well as printing and postage costs (approx. €300).

Publisher Copyright:
© 2021 The Authors

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

SDG 3 Good Health and Well-being

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Cite this

Schluep, M., Endeman, H., Gravesteijn, B. Y., Kuijs, C., Blans, M. J., van den Bogaard, B., Van Gemert, A. W. M. M. K., Hukshorn, C. J., van der Meer, B. J. M., Knook, A. H. M., van Melsen, T., Peters, R., Simons, K. S., Spijkers, G., Vermeijden, J. W., Wils, E. J., Stolker, R. J., & Hoeks, S. E. (2022). In-depth assessment of health-related quality of life after in-hospital cardiac arrest. Journal of Critical Care, 68, 22-30. https://doi.org/10.1016/j.jcrc.2021.11.008

@article{0c595789a52d4cc5b118a337b52a7fc3,

title = "In-depth assessment of health-related quality of life after in-hospital cardiac arrest",

abstract = "Introduction: Evidence on physical and psychological well-being of in-hospital cardiac arrest (IHCA) survivors is scarce. The aim of this study is to describe long-term health-related quality of life (HRQoL), functional independence and psychological distress 3 and 12 months post-IHCA. Methods: A multicenter prospective cohort study in 25 hospitals between January 2017 – May 2018. Adult IHCA survivors were included. HRQoL (EQ-5D-5L, SF-12), psychological distress (HADS, CSI) and functional independence (mRS) were assessed at 3 and 12 months post-IHCA. Results: At 3-month follow-up 136 of 212 survivors responded to the questionnaire and at 12 months 110 of 198 responded. The median (IQR) EQ-utility Index score was 0.77 (0.65–0.87) at 3 months and 0.81 (0.70–0.91) at 12 months. At 3 months, patients reported a median SF-12 (IQR) physical component scale (PCS) of 38.9 (32.8–46.5) and mental component scale (MCS) of 43.5 (34.0–39.7) and at 12 months a PCS of 43.1 (34.6–52.3) and MCS 46.9 (38.5–54.5). Discussion: Using various tools most IHCA survivors report an acceptable HRQoL and a substantial part experiences lower HRQoL compared to population norms. Our data suggest that younger (male) patients and those with poor functional status prior to admission are at highest risk of impaired HRQoL.",

author = "M. Schluep and H. Endeman and Gravesteijn, \{B. Y.\} and C. Kuijs and Blans, \{M. J.\} and \{van den Bogaard\}, B. and \{Van Gemert\}, \{A. W.M.M.Koopman\} and Hukshorn, \{C. J.\} and \{van der Meer\}, \{B. J.M.\} and Knook, \{A. H.M.\} and \{van Melsen\}, T. and R. Peters and Simons, \{K. S.\} and G. Spijkers and Vermeijden, \{J. W.\} and Wils, \{E. J.\} and Stolker, \{R. J.\} and Hoeks, \{S. E.\}",

note = "Funding Information: This study was funded by Departmental Funds of the Participating Hospitals . Licensing of the SF-12 software (€800) was funded by the ESA Air Liquide unrestricted research grant 2017, as well as printing and postage costs (approx. €300). Publisher Copyright: {\textcopyright} 2021 The Authors",

year = "2022",

doi = "10.1016/j.jcrc.2021.11.008",

language = "English",

volume = "68",

pages = "22--30",

journal = "Journal of Critical Care",

issn = "0883-9441",

publisher = "W.B. Saunders",

}

Schluep, M , Endeman, H, Gravesteijn, BY, Kuijs, C, Blans, MJ, van den Bogaard, B, Van Gemert, AWMMK, Hukshorn, CJ, van der Meer, BJM, Knook, AHM, van Melsen, T, Peters, R, Simons, KS, Spijkers, G, Vermeijden, JW, Wils, EJ, Stolker, RJ & Hoeks, SE 2022, 'In-depth assessment of health-related quality of life after in-hospital cardiac arrest', Journal of Critical Care, vol. 68, pp. 22-30. https://doi.org/10.1016/j.jcrc.2021.11.008

TY - JOUR

T1 - In-depth assessment of health-related quality of life after in-hospital cardiac arrest

AU - Schluep, M.

AU - Endeman, H.

AU - Gravesteijn, B. Y.

AU - Kuijs, C.

AU - Blans, M. J.

AU - van den Bogaard, B.

AU - Van Gemert, A. W.M.M.Koopman

AU - Hukshorn, C. J.

AU - van der Meer, B. J.M.

AU - Knook, A. H.M.

AU - van Melsen, T.

AU - Peters, R.

AU - Simons, K. S.

AU - Spijkers, G.

AU - Vermeijden, J. W.

AU - Wils, E. J.

AU - Stolker, R. J.

AU - Hoeks, S. E.

N1 - Funding Information: This study was funded by Departmental Funds of the Participating Hospitals . Licensing of the SF-12 software (€800) was funded by the ESA Air Liquide unrestricted research grant 2017, as well as printing and postage costs (approx. €300). Publisher Copyright: © 2021 The Authors

PY - 2022

Y1 - 2022

N2 - Introduction: Evidence on physical and psychological well-being of in-hospital cardiac arrest (IHCA) survivors is scarce. The aim of this study is to describe long-term health-related quality of life (HRQoL), functional independence and psychological distress 3 and 12 months post-IHCA. Methods: A multicenter prospective cohort study in 25 hospitals between January 2017 – May 2018. Adult IHCA survivors were included. HRQoL (EQ-5D-5L, SF-12), psychological distress (HADS, CSI) and functional independence (mRS) were assessed at 3 and 12 months post-IHCA. Results: At 3-month follow-up 136 of 212 survivors responded to the questionnaire and at 12 months 110 of 198 responded. The median (IQR) EQ-utility Index score was 0.77 (0.65–0.87) at 3 months and 0.81 (0.70–0.91) at 12 months. At 3 months, patients reported a median SF-12 (IQR) physical component scale (PCS) of 38.9 (32.8–46.5) and mental component scale (MCS) of 43.5 (34.0–39.7) and at 12 months a PCS of 43.1 (34.6–52.3) and MCS 46.9 (38.5–54.5). Discussion: Using various tools most IHCA survivors report an acceptable HRQoL and a substantial part experiences lower HRQoL compared to population norms. Our data suggest that younger (male) patients and those with poor functional status prior to admission are at highest risk of impaired HRQoL.

AB - Introduction: Evidence on physical and psychological well-being of in-hospital cardiac arrest (IHCA) survivors is scarce. The aim of this study is to describe long-term health-related quality of life (HRQoL), functional independence and psychological distress 3 and 12 months post-IHCA. Methods: A multicenter prospective cohort study in 25 hospitals between January 2017 – May 2018. Adult IHCA survivors were included. HRQoL (EQ-5D-5L, SF-12), psychological distress (HADS, CSI) and functional independence (mRS) were assessed at 3 and 12 months post-IHCA. Results: At 3-month follow-up 136 of 212 survivors responded to the questionnaire and at 12 months 110 of 198 responded. The median (IQR) EQ-utility Index score was 0.77 (0.65–0.87) at 3 months and 0.81 (0.70–0.91) at 12 months. At 3 months, patients reported a median SF-12 (IQR) physical component scale (PCS) of 38.9 (32.8–46.5) and mental component scale (MCS) of 43.5 (34.0–39.7) and at 12 months a PCS of 43.1 (34.6–52.3) and MCS 46.9 (38.5–54.5). Discussion: Using various tools most IHCA survivors report an acceptable HRQoL and a substantial part experiences lower HRQoL compared to population norms. Our data suggest that younger (male) patients and those with poor functional status prior to admission are at highest risk of impaired HRQoL.

UR - https://www.scopus.com/pages/publications/85120165860

U2 - 10.1016/j.jcrc.2021.11.008

DO - 10.1016/j.jcrc.2021.11.008

M3 - Article

C2 - 34856490

AN - SCOPUS:85120165860

SN - 0883-9441

VL - 68

SP - 22

EP - 30

JO - Journal of Critical Care

JF - Journal of Critical Care

ER -

In-depth assessment of health-related quality of life after in-hospital cardiac arrest

Abstract

Bibliographical note

UN SDGs

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