In Vivo Assessment of Mitochondrial Oxygen Consumption

Floor A. Harms, Egbert G. Mik*

*Corresponding author for this work

Research output: Chapter/Conference proceedingChapterAcademic

1 Citation (Scopus)


The Protoporphyrin IX–Triplet State Lifetime Technique (PpIX-TSLT) has been proposed by us as a potential clinical noninvasive tool for monitoring mitochondrial function. We have been working on the development of mitochondrial respirometry for monitoring mitochondrial oxygen tension (mitoPO2) and mitochondrial oxygen consumption (mitoVO2) in skin. In this work, we describe the principles of the method in small experimental animals.

Original languageEnglish
Title of host publicationMitochondrial Medicine
Subtitle of host publicationVolume 3: Manipulating Mitochondria and Disease-Specific Approaches
EditorsVolkmar Weissig, Marvin Edeas
Number of pages11
EditionSecond Edition
ISBN (Electronic)978-1-0716-1270-5
Publication statusPublished - 3 Jun 2021

Publication series

SeriesMethods in Molecular Biology

Bibliographical note

Publisher Copyright: © 2021, Springer Science+Business Media, LLC, part of Springer Nature.


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