In Vivo Assessment of Mitochondrial Oxygen Consumption

Floor A. Harms; Egbert G. Mik

doi:10.1007/978-1-0716-1270-5_12

In Vivo Assessment of Mitochondrial Oxygen Consumption

Floor A. Harms, Egbert G. Mik^*

^*Corresponding author for this work

Anesthesiology

Research output: Chapter/Conference proceeding › Chapter › Academic

1 Citation (Scopus)

Abstract

The Protoporphyrin IX–Triplet State Lifetime Technique (PpIX-TSLT) has been proposed by us as a potential clinical noninvasive tool for monitoring mitochondrial function. We have been working on the development of mitochondrial respirometry for monitoring mitochondrial oxygen tension (mitoPO₂) and mitochondrial oxygen consumption (mitoVO₂) in skin. In this work, we describe the principles of the method in small experimental animals.

Original language	English
Title of host publication	Mitochondrial Medicine
Pages	175-185
Number of pages	11
ISBN (Electronic)	978-1-0716-1270-5
DOIs	https://doi.org/10.1007/978-1-0716-1270-5_12
Publication status	Published - 3 Jun 2021

Publication series

Series	Methods in Molecular Biology
ISSN	1064-3745

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Publisher Copyright:
© 2021, Springer Science+Business Media, LLC, part of Springer Nature.

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In Vivo Assessment of Mitochondrial Oxygen Consumption

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