In vivo models to study the pathogenesis of extra‐respiratory complications of influenza a virus infection

Edwin Veldhuis Kroeze, Lisa Bauer, Valentina Caliendo, Debby van Riel*

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

3 Citations (Scopus)
1 Downloads (Pure)

Abstract

Animal models are an inimitable method to study the systemic pathogenesis of virus-induced disease. Extra‐respiratory complications of influenza A virus infections are not extensively studied even though they are often associated with severe disease and mortality. Here we review and recommend mammalian animal models that can be used to study extra‐respiratory complications of the central nervous system and cardiovascular system as well as involvement of the eye, placenta, fetus, lacteal gland, liver, pancreas, intestinal tract, and lymphoid tissues during influenza A virus infections.

Original languageEnglish
Article number848
JournalViruses
Volume13
Issue number5
DOIs
Publication statusPublished - 6 May 2021

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