Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters

KWK Cheung; Bianca Groen; GJ Burckart; L Zhang; Saskia de Wildt; SM Huang

doi:10.1002/jcph.1489

Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters

KWK Cheung, Bianca Groen, GJ Burckart, L Zhang, Saskia de Wildt, SM Huang

Pediatric Surgery

Research output: Contribution to journal › Article › Academic › peer-review

38 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	S56-S69
Journal	Journal of Clinical Pharmacology
Volume	59
DOIs	https://doi.org/10.1002/jcph.1489
Publication status	Published - 2019

Research programs

EMC OR-01

Access to Document

10.1002/jcph.1489

http://hdl.handle.net/1765/121299

Cite this

@article{ed538e4c66264ed39e9b8f2c80b8b113,

title = "Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters",

author = "KWK Cheung and Bianca Groen and GJ Burckart and L Zhang and {de Wildt}, Saskia and SM Huang",

year = "2019",

doi = "10.1002/jcph.1489",

language = "Undefined/Unknown",

volume = "59",

pages = "S56--S69",

journal = "Journal of Clinical Pharmacology",

issn = "0091-2700",

publisher = "Wiley-Blackwell",

}

Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters. / Cheung, KWK; Groen, Bianca; Burckart, GJ et al.
In: Journal of Clinical Pharmacology, Vol. 59, 2019, p. S56-S69.

Research output: Contribution to journal › Article › Academic › peer-review

TY - JOUR

T1 - Incorporating Ontogeny in Physiologically Based Pharmacokinetic Modeling to Improve Pediatric Drug Development: What We Know About Developmental Changes in Membrane Transporters

AU - Cheung, KWK

AU - Groen, Bianca

AU - Burckart, GJ

AU - Zhang, L

AU - de Wildt, Saskia

AU - Huang, SM

PY - 2019

Y1 - 2019

U2 - 10.1002/jcph.1489

DO - 10.1002/jcph.1489

M3 - Article

C2 - 31502692

SN - 0091-2700

VL - 59

SP - S56-S69

JO - Journal of Clinical Pharmacology

JF - Journal of Clinical Pharmacology

ER -