Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology

F Hammiche, Marijana Vujkovic, W Wijburg, JH (Jeanne) de Vries, Macklon, Joop Laven, Régine Steegers - Theunissen

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The association between preconception dietary intake of the polyunsaturated fatty acids (LC-PUFAs) omega-6 and omega-3 and the E(2) levels and IVF/intracytoplasmic sperm injection (ICSI) outcome were investigated in women in a prospective study. It revealed that high intakes of omega-3 LC-PUFA alpha-linolenic acid increase baseline E(2), high intakes of eicosapentaenoic acid and docosahexaenoic acid reduce E(2) response and the number of follicles after ovarian stimulation, and total omega-3 intake, in particular alpha-linolenic acid and docosahexaenoic acid, improve embryo morphology. (Fertil Steril (R) 2011; 95: 1820-3. (C) 2011 by American Society for Reproductive Medicine.)
Original languageUndefined/Unknown
Pages (from-to)1820-1823
Number of pages4
JournalFertility & Sterility
Issue number5
Publication statusPublished - 2011

Research programs

  • EMC MGC-02-52-01-A
  • EMC MGC-02-96-01
  • EMC MM-01-52-07

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