Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology

F Hammiche; Marijana Vujkovic; W Wijburg; JH (Jeanne) de Vries; Macklon; Joop Laven; Régine Steegers - Theunissen

doi:10.1016/j.fertnstert.2010.11.021

Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology

F Hammiche
, Marijana Vujkovic
, W Wijburg
, JH (Jeanne) de Vries
, Macklon
, Joop Laven
, Régine Steegers - Theunissen

Research output: Contribution to journal › Article › Academic › peer-review

119 Citations (Scopus)

Abstract

The association between preconception dietary intake of the polyunsaturated fatty acids (LC-PUFAs) omega-6 and omega-3 and the E(2) levels and IVF/intracytoplasmic sperm injection (ICSI) outcome were investigated in women in a prospective study. It revealed that high intakes of omega-3 LC-PUFA alpha-linolenic acid increase baseline E(2), high intakes of eicosapentaenoic acid and docosahexaenoic acid reduce E(2) response and the number of follicles after ovarian stimulation, and total omega-3 intake, in particular alpha-linolenic acid and docosahexaenoic acid, improve embryo morphology. (Fertil Steril (R) 2011; 95: 1820-3. (C) 2011 by American Society for Reproductive Medicine.)

Original language	Undefined/Unknown
Pages (from-to)	1820-1823
Number of pages	4
Journal	Fertility & Sterility
Volume	95
Issue number	5
DOIs	https://doi.org/10.1016/j.fertnstert.2010.11.021
Publication status	Published - 2011

Research programs

EMC MGC-02-52-01-A
EMC MGC-02-96-01
EMC MM-01-52-07

Access to Document

10.1016/j.fertnstert.2010.11.021

http://hdl.handle.net/1765/21877

Cite this

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title = "Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology",

abstract = "The association between preconception dietary intake of the polyunsaturated fatty acids (LC-PUFAs) omega-6 and omega-3 and the E(2) levels and IVF/intracytoplasmic sperm injection (ICSI) outcome were investigated in women in a prospective study. It revealed that high intakes of omega-3 LC-PUFA alpha-linolenic acid increase baseline E(2), high intakes of eicosapentaenoic acid and docosahexaenoic acid reduce E(2) response and the number of follicles after ovarian stimulation, and total omega-3 intake, in particular alpha-linolenic acid and docosahexaenoic acid, improve embryo morphology. (Fertil Steril (R) 2011; 95: 1820-3. (C) 2011 by American Society for Reproductive Medicine.)",

author = "F Hammiche and Marijana Vujkovic and W Wijburg and \{de Vries\}, \{JH (Jeanne)\} and Macklon and Joop Laven and \{Steegers - Theunissen\}, R{\'e}gine",

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doi = "10.1016/j.fertnstert.2010.11.021",

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TY - JOUR

T1 - Increased preconception omega-3 polyunsaturated fatty acid intake improves embryo morphology

AU - Hammiche, F

AU - Vujkovic, Marijana

AU - Wijburg, W

AU - de Vries, JH (Jeanne)

AU - Macklon, null

AU - Laven, Joop

AU - Steegers - Theunissen, Régine

PY - 2011

Y1 - 2011

N2 - The association between preconception dietary intake of the polyunsaturated fatty acids (LC-PUFAs) omega-6 and omega-3 and the E(2) levels and IVF/intracytoplasmic sperm injection (ICSI) outcome were investigated in women in a prospective study. It revealed that high intakes of omega-3 LC-PUFA alpha-linolenic acid increase baseline E(2), high intakes of eicosapentaenoic acid and docosahexaenoic acid reduce E(2) response and the number of follicles after ovarian stimulation, and total omega-3 intake, in particular alpha-linolenic acid and docosahexaenoic acid, improve embryo morphology. (Fertil Steril (R) 2011; 95: 1820-3. (C) 2011 by American Society for Reproductive Medicine.)

AB - The association between preconception dietary intake of the polyunsaturated fatty acids (LC-PUFAs) omega-6 and omega-3 and the E(2) levels and IVF/intracytoplasmic sperm injection (ICSI) outcome were investigated in women in a prospective study. It revealed that high intakes of omega-3 LC-PUFA alpha-linolenic acid increase baseline E(2), high intakes of eicosapentaenoic acid and docosahexaenoic acid reduce E(2) response and the number of follicles after ovarian stimulation, and total omega-3 intake, in particular alpha-linolenic acid and docosahexaenoic acid, improve embryo morphology. (Fertil Steril (R) 2011; 95: 1820-3. (C) 2011 by American Society for Reproductive Medicine.)

U2 - 10.1016/j.fertnstert.2010.11.021

DO - 10.1016/j.fertnstert.2010.11.021

M3 - Article

C2 - 21130435

SN - 0015-0282

VL - 95

SP - 1820

EP - 1823

JO - Fertility & Sterility

JF - Fertility & Sterility

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