Infections and the Guillain-Barre Syndrome: from endemic to pandemic

Sonja Leonhard

Infections and the Guillain-Barre Syndrome: from endemic to pandemic

Sonja Leonhard

Medical Microbiology & Infectious Diseases

Research output: Types of Thesis › Doctoral Thesis › Internal

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Abstract

The Guillain-Barré syndrome (GBS) is an inflammatory disease of the peripheral nervous system and a rare complication of infectious diseases. Endemic infections occurring at a high rate, epidemics, or vaccine campaigns may induce peaks in the incidence of GBS. A recent example includes the Zika virus which caused a high incidence of GBS in Latin America. In this thesis the role of this and several other infectious diseases in the development of GBS are investigated. Furthermore, the limitations in diagnosis and management of GBS that clinicians experience globally are studied and opportunities to improve this in preparation of future outbreaks are explored.

Original language	English
Awarding Institution	Erasmus University Rotterdam
Supervisors/Advisors	Jacobs, B.C., Supervisor Willison, Hugh J., Supervisor
Award date	14 Jun 2022
Place of Publication	Rotterdam
Print ISBNs	978-94-6361-707-9
Publication status	Published - 14 Jun 2022

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title = "Infections and the Guillain-Barre Syndrome: from endemic to pandemic",

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T2 - from endemic to pandemic

AU - Leonhard, Sonja

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N2 - The Guillain-Barré syndrome (GBS) is an inflammatory disease of the peripheral nervous system and a rare complication of infectious diseases. Endemic infections occurring at a high rate, epidemics, or vaccine campaigns may induce peaks in the incidence of GBS. A recent example includes the Zika virus which caused a high incidence of GBS in Latin America. In this thesis the role of this and several other infectious diseases in the development of GBS are investigated. Furthermore, the limitations in diagnosis and management of GBS that clinicians experience globally are studied and opportunities to improve this in preparation of future outbreaks are explored.

AB - The Guillain-Barré syndrome (GBS) is an inflammatory disease of the peripheral nervous system and a rare complication of infectious diseases. Endemic infections occurring at a high rate, epidemics, or vaccine campaigns may induce peaks in the incidence of GBS. A recent example includes the Zika virus which caused a high incidence of GBS in Latin America. In this thesis the role of this and several other infectious diseases in the development of GBS are investigated. Furthermore, the limitations in diagnosis and management of GBS that clinicians experience globally are studied and opportunities to improve this in preparation of future outbreaks are explored.

M3 - Doctoral Thesis

SN - 978-94-6361-707-9

CY - Rotterdam

ER -

Infections and the Guillain-Barre Syndrome: from endemic to pandemic

Abstract

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