Influence of Minimally Invasive Resection Technique on Sphincter Preservation and Short-term Outcome in Low Rectal Cancer in the Netherlands

Marieke L. Rutgers, Robin Detering, Sapho X. Roodbeen, Rogier M. Crolla, Jan Willem T. Dekker, Jurriaan B. Tuynman, Colin Sietses, Willem A. Bemelman, Pieter J. Tanis, Roel Hompes*

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

9 Citations (Scopus)

Abstract

BACKGROUND: 

Transanal and robotic-assisted total mesorectal excision are techniques that can potentially overcome challenges encountered with a pure laparoscopic approach in patients with rectal cancer. 

OBJECTIVE: 

The aim of this study was to evaluate the proportion and predictive factors of restorative procedures and subsequent short-term outcomes of 3 minimally invasive techniques to treat low rectal cancer. 

DESIGN: 

This is a nationwide observational comparative registry study. 

SETTINGS: 

Patients with rectal cancer were selected from the mandatory Dutch ColoRectal Audit. 

PATIENTS: 

Patients with low rectal cancer (≤5 cm) who underwent curative minimally invasive total mesorectal excision between 2015 and 2018 were included. 

MAIN OUTCOME MEASURES: 

The primary outcomes measured were the proportion of restorative procedure, positive circumferential resection margin, and postoperative complications. 

RESULTS: 

A total of 3466 patients were included for analysis, of which 33% underwent a restorative procedure. Resections were performed laparoscopically in 2845 patients, transanally in 448 patients, and were robot-assisted in 173 patients, with a proportion of restorative procedures of 28%, 66%, and 40%. The transanal approach was independently associated with a restorative procedure (OR, 4.11; 95% CI, 3.21-5.26; p < 0.001). Independent risk factors for a nonrestorative procedure, irrespective of the surgical technique, were age >75 years, ASA physical status ≥3, BMI >30, history of abdominal surgery, clinical T4-stage, mesorectal fascia ≤1 mm, neoadjuvant therapy, and having a procedure in 2015 to 2016 versus 2017 to 2018. The circumferential resection margin involvement was similar for all 3 groups (5.4%, 5.1%, and 5.1%). Short-term postoperative complications were less favorable for the newer techniques than for the laparoscopic approach. 

LIMITATIONS: 

This study was limited because of the registry's variables and different group sizes. 

CONCLUSION: 

Patients with low rectal cancer in the Netherlands are more likely to receive a restorative procedure with a transanal approach, compared with a laparoscopic or robotic procedure. Short-term oncological outcomes are comparable between the 3 minimally invasive techniques.

Original languageEnglish
Pages (from-to)1488-1500
Number of pages13
JournalDiseases of the Colon and Rectum
Volume64
Issue number12
DOIs
Publication statusPublished - Dec 2021

Bibliographical note

Publisher Copyright:
© 2021 Lippincott Williams and Wilkins. All rights reserved.

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