Initially obscure hepatotoxicity attributed to sildenafil

FHJ (Franciscus) Wolfhagen; HG (Hester) Vermeulen; Rob de Man; W Lesterhuis

doi:10.1097/MEG.0b013e3282f2bbb5

Initially obscure hepatotoxicity attributed to sildenafil

FHJ (Franciscus) Wolfhagen, HG (Hester) Vermeulen, Rob de Man, W Lesterhuis

Gastroenterology & Hepatology

Research output: Contribution to journal › Article › Academic › peer-review

15 Citations (Scopus)

Abstract

We describe a patient with a hepatotoxic reaction, presenting with general malaise, severe jaundice, and pruritus. This turned out to be caused by the, at first unrevealed, use of sildenafil. The injury seems to be hepatocanalicular, characterized by a hepatocellular liver test pattern, combined with extensive cholestasis on liver biopsy. One should bare in mind that the use of sildenafil may not be readily disclosed by the patient nor his doctor.

Original language	Undefined/Unknown
Pages (from-to)	710-712
Number of pages	3
Journal	European Journal of Gastroenterology & Hepatology
Volume	20
Issue number	7
DOIs	https://doi.org/10.1097/MEG.0b013e3282f2bbb5
Publication status	Published - 2008

Research programs

EMC MM-04-20-02-A

Access to Document

10.1097/MEG.0b013e3282f2bbb5

http://hdl.handle.net/1765/29920

Cite this

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