Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

Jun Liu; Lies Lahousse; MG Nivard; M Bot; LM Chen; JB van Klinken; CS Thesing; M Beekman; EB van den Akker; R C Slieker; E Waterham; CJH van der Kallen; I Boer; RF Li-Gao; Dina Vojinovic; Najaf Amin; Djawad Radjabzadeh; Robert Kraaij; Loes Alferink; Sarwa Darwish Murad; André Uitterlinden; G Willemsen; R Pool; Y Milaneschi; D van Heemst; H E Suchiman; F Rutters; PJM Elders; JW Beulens; A Heijden; MMJ van Greevenbroek; ICW Arts; GLJ Onderwater; A van den Maagdenberg; Dennis Mook; T Hankemeier; GM Terwindt; CD Stehouwer; JM Geleijnse; Lm'T Hart; PE (Eline) Slagboom; KW van Dijk; A Zhernakova; JY Fu; B Penninx; DI Boomsma; A Demirkan; Bruno Stricker; Cornelia Duijn

doi:10.1038/s41591-019-0722-x

Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

Jun Liu, Lies Lahousse, MG Nivard, M Bot, LM Chen, JB van Klinken, CS Thesing, M Beekman, EB van den Akker, R C Slieker, E Waterham, CJH van der Kallen, I Boer, RF Li-Gao, Dina Vojinovic, Najaf Amin, Djawad Radjabzadeh, Robert Kraaij, Loes Alferink, Sarwa Darwish MuradAndré Uitterlinden, G Willemsen, R Pool, Y Milaneschi, D van Heemst, H E Suchiman, F Rutters, PJM Elders, JW Beulens, A Heijden, MMJ van Greevenbroek, ICW Arts, GLJ Onderwater, A van den Maagdenberg, Dennis Mook, T Hankemeier, GM Terwindt, CD Stehouwer, JM Geleijnse, Lm'T Hart, PE (Eline) Slagboom, KW van Dijk, A Zhernakova, JY Fu, B Penninx, DI Boomsma, A Demirkan, Bruno Stricker, Cornelia Duijn

Research output: Contribution to journal › Article › Academic › peer-review

29 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	110-+
Journal	Nature Medicine
Volume	26
Issue number	1
DOIs	https://doi.org/10.1038/s41591-019-0722-x
Publication status	Published - 2020

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Liu, J., Lahousse, L., Nivard, MG., Bot, M., Chen, LM., van Klinken, JB., Thesing, CS., Beekman, M., van den Akker, EB., Slieker, R. C., Waterham, E., van der Kallen, CJH., Boer, I., Li-Gao, RF., Vojinovic, D., Amin, N., Radjabzadeh, D., Kraaij, R., Alferink, L., ... Duijn, C. (2020). Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas. Nature Medicine, 26(1), 110-+. https://doi.org/10.1038/s41591-019-0722-x

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author = "Jun Liu and Lies Lahousse and MG Nivard and M Bot and LM Chen and {van Klinken}, JB and CS Thesing and M Beekman and {van den Akker}, EB and Slieker, {R C} and E Waterham and {van der Kallen}, CJH and I Boer and RF Li-Gao and Dina Vojinovic and Najaf Amin and Djawad Radjabzadeh and Robert Kraaij and Loes Alferink and {Darwish Murad}, Sarwa and Andr{\'e} Uitterlinden and G Willemsen and R Pool and Y Milaneschi and {van Heemst}, D and Suchiman, {H E} and F Rutters and PJM Elders and JW Beulens and A Heijden and {van Greevenbroek}, MMJ and ICW Arts and GLJ Onderwater and {van den Maagdenberg}, A and Dennis Mook and T Hankemeier and GM Terwindt and CD Stehouwer and JM Geleijnse and Lm'T Hart and Slagboom, {PE (Eline)} and {van Dijk}, KW and A Zhernakova and JY Fu and B Penninx and DI Boomsma and A Demirkan and Bruno Stricker and Cornelia Duijn",

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Liu, J, Lahousse, L, Nivard, MG, Bot, M, Chen, LM, van Klinken, JB, Thesing, CS, Beekman, M, van den Akker, EB, Slieker, RC, Waterham, E, van der Kallen, CJH, Boer, I, Li-Gao, RF, Vojinovic, D, Amin, N , Radjabzadeh, D , Kraaij, R , Alferink, L , Darwish Murad, S , Uitterlinden, A, Willemsen, G, Pool, R, Milaneschi, Y, van Heemst, D, Suchiman, HE, Rutters, F, Elders, PJM, Beulens, JW, Heijden, A, van Greevenbroek, MMJ, Arts, ICW, Onderwater, GLJ, van den Maagdenberg, A, Mook, D, Hankemeier, T, Terwindt, GM, Stehouwer, CD, Geleijnse, JM, Hart, LT, Slagboom, PE, van Dijk, KW, Zhernakova, A, Fu, JY, Penninx, B, Boomsma, DI, Demirkan, A, Stricker, B & Duijn, C 2020, 'Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas', Nature Medicine, vol. 26, no. 1, pp. 110-+. https://doi.org/10.1038/s41591-019-0722-x

TY - JOUR

T1 - Integration of epidemiologic, pharmacologic, genetic and gut microbiome data in a drug-metabolite atlas

AU - Liu, Jun

AU - Lahousse, Lies

AU - Nivard, MG

AU - Bot, M

AU - Chen, LM

AU - van Klinken, JB

AU - Thesing, CS

AU - Beekman, M

AU - van den Akker, EB

AU - Slieker, R C

AU - Waterham, E

AU - van der Kallen, CJH

AU - Boer, I

AU - Li-Gao, RF

AU - Vojinovic, Dina

AU - Amin, Najaf

AU - Radjabzadeh, Djawad

AU - Kraaij, Robert

AU - Alferink, Loes

AU - Darwish Murad, Sarwa

AU - Uitterlinden, André

AU - Willemsen, G

AU - Pool, R

AU - Milaneschi, Y

AU - van Heemst, D

AU - Suchiman, H E

AU - Rutters, F

AU - Elders, PJM

AU - Beulens, JW

AU - Heijden, A

AU - van Greevenbroek, MMJ

AU - Arts, ICW

AU - Onderwater, GLJ

AU - van den Maagdenberg, A

AU - Mook, Dennis

AU - Hankemeier, T

AU - Terwindt, GM

AU - Stehouwer, CD

AU - Geleijnse, JM

AU - Hart, Lm'T

AU - Slagboom, PE (Eline)

AU - van Dijk, KW

AU - Zhernakova, A

AU - Fu, JY

AU - Penninx, B

AU - Boomsma, DI

AU - Demirkan, A

AU - Stricker, Bruno

AU - Duijn, Cornelia

PY - 2020

Y1 - 2020

U2 - 10.1038/s41591-019-0722-x

DO - 10.1038/s41591-019-0722-x

M3 - Article

SN - 1078-8956

VL - 26

SP - 110-+

JO - Nature Medicine

JF - Nature Medicine

IS - 1

ER -