Integrative diagnostics: the time is now—a report from the International Society for Strategic Studies in Radiology

Norman J. Beauchamp, R. Nick Bryan*, Marilyn M. Bui, Gabriel P. Krestin, Geraldine B. McGinty, Carolyn C. Meltzer, Michael Neumaier

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

3 Citations (Scopus)
25 Downloads (Pure)


Abstract: Enormous recent progress in diagnostic testing can enable more accurate diagnosis and improved clinical outcomes. Yet these tests are increasingly challenging and frustrating; the volume and diversity of results may overwhelm the diagnostic acumen of even the most dedicated and experienced clinician. Because they are gathered and processed within the “silo” of each diagnostic discipline, diagnostic data are fragmented, and the electronic health record does little to synthesize new and existing data into usable information. Therefore, despite great promise, diagnoses may still be incorrect, delayed, or never made. Integrative diagnostics represents a vision for the future, wherein diagnostic data, together with clinical data from the electronic health record, are aggregated and contextualized by informatics tools to direct clinical action. Integrative diagnostics has the potential to identify correct therapies more quickly, modify treatment when appropriate, and terminate treatment when not effective, ultimately decreasing morbidity, improving outcomes, and avoiding unnecessary costs. Radiology, laboratory medicine, and pathology already play major roles in medical diagnostics. Our specialties can increase the value of our examinations by taking a holistic approach to their selection, interpretation, and application to the patient’s care pathway. We have the means and rationale to incorporate integrative diagnostics into our specialties and guide its implementation in clinical practice. Graphic abstract: [Figure not available: see fulltext.].

Original languageEnglish
Article number54
JournalInsights into Imaging
Issue number1
Publication statusPublished - 30 Mar 2023

Bibliographical note

This paper is published simultaneously in the Journal of the American College of Radiology (DOI: 10.1016/j.jacr.2022.11.015) and Insights into Imaging (DOI: 10.1186/s13244-023-01379-9).

Publisher Copyright:
© 2023, The Author(s).


Dive into the research topics of 'Integrative diagnostics: the time is now—a report from the International Society for Strategic Studies in Radiology'. Together they form a unique fingerprint.

Cite this