Interdisciplinary structural follow-up of surgical newborns: a prospective evaluation

S.J. Gischler, Petra Mazer, Hugo Duivenvoorden, Klaas Bax, Monique van Dijk, FWJ (Frans) Hazebroek, Dick Tibboel

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104 Citations (Scopus)


Background: Information on physical and developmental outcomes of children with anatomical congenital anomalies (CAs) may indicate the need for early intervention and reduce impact on the child's life and parental burden. Methods: From 1999 to 2003, 101 children with CA (76.5% of initial survivors) were seen 6-monthly in a tertiary children's hospital. Growth, neurologic outcome, mental and psychomotor development as determined with the Bayley Scales of Infant Development, and categorization of predictive sociodemographic and medical variables of the children were evaluated prospectively and longitudinally. Results: Congenital diaphragmatic hernia (CDH) and esophageal atresia patients showed impaired growth, that is, both height for age (-1.5 standard deviation score [SDS]) and weight for height (-1.0 SDS). Overall neurologic Outcome was normal, however, suspect or abnormal for 40% of CDH patients. Overall mental development was normal, but psychomotor scores were significantly lower than the norm (95% confidence interval, 83.8-92.2 at 6 months and 87.9-98.5 at 24 months). Sex, maternal age, socioeconomic status, CA, severity-of-disease covariables, and need of medical appliances at home could predict negative outcome significantly (P <.05). Conclusions: The CA survivors show impaired growth and psychomotor developmental delay up to age 2 years. This warrants specific follow-up programs and infrastructure for these patients. (C) 2009 Elsevier Inc. All rights reserved.
Original languageUndefined/Unknown
Pages (from-to)1382-1389
Number of pages8
JournalJournal of Pediatric Surgery
Issue number7
Publication statusPublished - 2009

Research programs

  • EMC MGC-02-53-01-A
  • EMC OR-02-54-06

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