TY - JOUR
T1 - Interictal cortical excitability to magnetic stimulation in familial hemiplegic migraine
AU - van der Kamp, Wim
AU - Maassen van den Brink, Antoinette
AU - Ferrari, Michel D.
AU - van Dijk, J. Gert
PY - 1997/5/1
Y1 - 1997/5/1
N2 - We studied interictal cortical excitability with magnetic stimulation in controls, in patients with migraine with aura, and in patients with familial hemiplegic migraine (FHM), in which ictal hemiparesis occurs. Amplitudes (p < 0.05) and amplitude ratios (p < 0.01) revealed heightened excitability in migraine with aura when compared to controls. In patients with FHM, mean thresholds were higher (p < 0.001) and conduction times longer (p < 0.01) than in controls. In FHM, amplitudes were lower on the ictally paretic side of the body than on the other (p < 0.05). Patients with FHM may have increased interictal cortical excitability, complicated by decreased excitability of the affected side.
AB - We studied interictal cortical excitability with magnetic stimulation in controls, in patients with migraine with aura, and in patients with familial hemiplegic migraine (FHM), in which ictal hemiparesis occurs. Amplitudes (p < 0.05) and amplitude ratios (p < 0.01) revealed heightened excitability in migraine with aura when compared to controls. In patients with FHM, mean thresholds were higher (p < 0.001) and conduction times longer (p < 0.01) than in controls. In FHM, amplitudes were lower on the ictally paretic side of the body than on the other (p < 0.05). Patients with FHM may have increased interictal cortical excitability, complicated by decreased excitability of the affected side.
U2 - 10.1212/WNL.48.5.1462
DO - 10.1212/WNL.48.5.1462
M3 - Comment/Letter to the editor
SN - 0028-3878
VL - 48
SP - 1462
EP - 1464
JO - Neurology
JF - Neurology
IS - 5
ER -