International Council for Standardization in Haematology (ICSH) laboratory guidance for the evaluation of haemostasis analyser-reagent test systems. Part 1: Instrument-specific issues and commonly used coagulation screening tests

Chris Gardiner*, Robyn Coleman, Moniek P.M. de Maat, Akbar Dorgalaleh, Marión Echenagucia, Robert C. Gosselin, Masahiro Ieko, Steve Kitchen

*Corresponding author for this work

Research output: Contribution to journalReview articleAcademicpeer-review

13 Citations (Scopus)
296 Downloads (Pure)

Abstract

Before a new method is used for clinical testing, it is essential that it is evaluated for suitability for its intended purpose. This document gives guidance for the performance of verification, validation and implementation processes required by regulatory and accreditation bodies. It covers the planning and execution of an evaluation of the commonly performed screening tests (prothrombin time, activated partial thromboplastin time, thrombin time and fibrinogen assay), and instrument-specific issues. Advice on selecting an appropriate haemostasis analyser, planning the evaluation, and assessing the reference, interval, precision, accuracy, and comparability of a haemostasis test system are also given. A second companion document will cover specialist haemostasis testing.

Original languageEnglish
Pages (from-to)169-183
Number of pages15
JournalInternational Journal of Laboratory Hematology
Volume43
Issue number2
Early online date29 Nov 2020
DOIs
Publication statusPublished - Apr 2021

Bibliographical note

Publisher Copyright:
© 2020 John Wiley & Sons Ltd

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