TY - JOUR
T1 - International Expert Consensus on Semantics of Multimodal Esophageal Cancer Treatment
T2 - Delphi Study
AU - van der Zijden, Charlène J.
AU - Study Coordinators of the Erasmus MC Cancer Institute
AU - For the International Expert Panel
AU - Lagarde, Sjoerd M.
AU - Mostert, Bianca
AU - Nuyttens, Joost J.M.E.
AU - Spaander, Manon C.W.
AU - Wijnhoven, Bas P.L.
AU - van Sandick, Johanna W.
AU - van Dieren, Jolanda M.
AU - Voncken, Francine E.M.
AU - Pierie, Jean Pierre E.N.
AU - Fiets, Willem E.
AU - Rosman, Camiel
AU - Siersema, Peter D.
AU - Rütten, Heidi
AU - Nieuwenhuijzen, Grard A.P.
AU - Creemers, Geert Jan
AU - Schoon, Erik J.
AU - van der Sangen, Maurice J.C.
AU - Verschoor, Arjan
AU - Quispel, Rutger
AU - Sosef, Meindert N.
AU - Buijsen, Jeroen
AU - Hartgrink, Hendrik H.
AU - Slingerland, Marije
AU - Heisterkamp, Joos
AU - Beerepoot, Laurens V.
AU - Hazen, Wouter L.
AU - Rozema, Tom
AU - Muller, Karin
AU - Kouwenhoven, Ewout A.
AU - Law, Simon Y.
AU - Chan, Wendy W.
AU - Wong, Ian Y.
AU - Li, Zhigang
AU - Chao, Yin Kai
AU - Wu, I. Chen
AU - Wu, Chiao En
AU - Yap, Wing Keen
AU - Park, Seong Yong
AU - Takeuchi, Hiroya
AU - Booka, Eisuke
AU - Kato, Ken
AU - Yoshinori, Ito
AU - Lin, Steven H.
AU - Piessen, Guillaume
AU - Turpin, Anthony
AU - Taillez, Alexandre
AU - Castoro, Carlo
AU - Bastoni, Alessandro
AU - Maselli, Roberta
N1 - Publisher Copyright:
© The Author(s) 2024.
PY - 2024/8
Y1 - 2024/8
N2 - Background: Recent developments in esophageal cancer treatment, including studies exploring active surveillance following chemoradiotherapy, have led to a need for clear terminology and definitions regarding different multimodal treatment options. Objective: The aim of this study was to reach worldwide consensus on the definitions and semantics of multimodal esophageal cancer treatment. Methods: In total, 72 experts working in the field of multimodal esophageal cancer treatment were invited to participate in this Delphi study. The study comprised three Delphi surveys sent out by email and one online meeting. Input for the Delphi survey consisted of terminology obtained from a systematic literature search. Participants were asked to respond to open questions and to indicate whether they agreed or disagreed with different statements. Consensus was reached when there was ≥75% agreement among respondents. Results: Forty-nine of 72 invited experts (68.1%) participated in the first online Delphi survey, 45 (62.5%) in the second survey, 21 (46.7%) of 45 in the online meeting, and 39 (86.7%) of 45 in the final survey. Consensus on neoadjuvant and definitive chemoradiotherapy with or without surgery was reached for 27 of 31 items (87%). No consensus was reached on follow-up after treatment with definitive chemoradiotherapy. Conclusion(s): Consensus was reached on most statements regarding terminology and definitions of multimodal esophageal cancer treatment. Implementing uniform criteria facilitates comparison of studies and promotes international research collaborations.
AB - Background: Recent developments in esophageal cancer treatment, including studies exploring active surveillance following chemoradiotherapy, have led to a need for clear terminology and definitions regarding different multimodal treatment options. Objective: The aim of this study was to reach worldwide consensus on the definitions and semantics of multimodal esophageal cancer treatment. Methods: In total, 72 experts working in the field of multimodal esophageal cancer treatment were invited to participate in this Delphi study. The study comprised three Delphi surveys sent out by email and one online meeting. Input for the Delphi survey consisted of terminology obtained from a systematic literature search. Participants were asked to respond to open questions and to indicate whether they agreed or disagreed with different statements. Consensus was reached when there was ≥75% agreement among respondents. Results: Forty-nine of 72 invited experts (68.1%) participated in the first online Delphi survey, 45 (62.5%) in the second survey, 21 (46.7%) of 45 in the online meeting, and 39 (86.7%) of 45 in the final survey. Consensus on neoadjuvant and definitive chemoradiotherapy with or without surgery was reached for 27 of 31 items (87%). No consensus was reached on follow-up after treatment with definitive chemoradiotherapy. Conclusion(s): Consensus was reached on most statements regarding terminology and definitions of multimodal esophageal cancer treatment. Implementing uniform criteria facilitates comparison of studies and promotes international research collaborations.
UR - http://www.scopus.com/inward/record.url?scp=85192392768&partnerID=8YFLogxK
U2 - 10.1245/s10434-024-15367-w
DO - 10.1245/s10434-024-15367-w
M3 - Article
C2 - 38717548
AN - SCOPUS:85192392768
SN - 1068-9265
VL - 31
SP - 5075
EP - 5082
JO - Annals of Surgical Oncology
JF - Annals of Surgical Oncology
IS - 8
ER -
