Introducing the importance and difficulties of a threestep approach to improve nonadherence to antihypertensive drugs: A case series

Laura E.J. Peeters*, Jeroen B. Van der Net, Kathy Schoenmakers-Buis, Irene M. Van der Meer, Emma K. Massey, Liset Van Dijk, Teun Van Gelder, Birgit C.P. Koch, Jorie Versmissen

*Corresponding author for this work

Research output: Contribution to journalArticleAcademicpeer-review

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Abstract

Nonadherence to antihypertensive drugs is an important reason for not reaching blood pressure goals. A possible method to improve nonadherence involves three essential steps: Identification of nonadherent patients (step 1), determination of underlying causes (step 2) and a personalized solution (step 3). We present three unique cases to show the importance and difficulties of this threestep approach. Patients participated in a randomized controlled trial to improve nonadherence to antihypertensive drugs (RHYMERCT, Dutch Trial Register NL6736). Drug level measurements were used to identify nonadherence to antihypertensive drugs and communication on drug levels was supported by a tailored feedback tool in these patients. These cases showed that a three-step approach of identifying nonadherence and determination of the underlying cause, can lead to a personalized solution to improve therapy even when nonadherence was excluded. Open communication with patients remains an essential part when improving nonadherence.

Original languageEnglish
Pages (from-to)189-193
Number of pages5
JournalJournal of Hypertension
Volume40
Issue number1
DOIs
Publication statusPublished - 1 Jan 2022

Bibliographical note

Funding Information:
Funding: This study was supported by a ZonMW grant for Rational Pharmacotherapy.

Publisher Copyright:
© 2022 Lippincott Williams and Wilkins. All rights reserved.

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