Is mechanical stress an important pathogenic factor in hidradenitis suppurativa?

K (K.) de Winter, Hessel van der Zee, Errol Prens

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Hidradenitis suppurativa (HS) is a chronic of recurrent, inflammatory, follicular disease that usually presents after puberty with painful deep-seated, inflamed lesions in the inverse skin areas of the body. It has been hypothesized that mechanical pressure or friction is a risk factor for HS. We describe the case of a man with a lower leg amputation who presented HS-like lesions on his leg stump after wearing a leg prosthesis. Although pilonidal sinus-like disease could not be excluded, we diagnosed him with HS-like lesions, induced by prosthesis-related friction. We argue that this case supports the concept that mechanical friction and a warm humid microclimate by occlusion contribute to HS development.
Original languageUndefined/Unknown
Pages (from-to)176-177
Number of pages2
JournalExperimental Dermatology
Issue number3
Publication statusPublished - 2012

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