Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

M.C. Zillikens; S Demissie; YH Hsu; LM Yerges-Armstrong; WC Chou; Lisette Stolk; G Livshits; Linda Broer; T Johnson; DL Koller; Z Kutalik; J Luan; I Malkin; JS Ried; AV Smith; G Thorleifsson; L Vandenput; JH Zhao; WH Zhang; A Aghdassi; K Akesson; Najaf Amin; LJ Baier; I Barroso; DA Bennett; L Bertram; R Biffar; M Bochud; M Boehnke; IB Borecki; AS Buchman; L Byberg; H Campbell; Natalia Campos Obando; JA Cauley; P M Cawthon; H Cederberg; Zhigang Chen; NH Cho; HJ Choi; M Claussnitzer; F Collins; SR Cummings; PL De Jager; I Demuth; RAM Dhonukshe-Rutten; L Diatchenko; G Eiriksdottir; Anke Enneman; M Erdos; JG Eriksson; J Eriksson; Karol Estrada Gil; DS Evans; MF Feitosa; M Fu; M Garcia; C Gieger; T Girke; NL Glazer; H Grallert; J Grewal; BG Han; RL Hanson; C Hayward; Bert Hofman; EP Hoffman; G Homuth; WC Hsueh; MJ Hubal; A Hubbard; KM Huffman; LB Husted; T Illig; E Ingelsson; T Ittermann; JO Jansson; JM Jordan; A Jula; M Karlsson; KT Khaw; TO Kilpainen; N Klopp; J Kloth; HA Koistinen; WE Kraus; S Kritchevsky; T Kuulasmaa; J Kuusisto; M Laakso; J Lahti; T Lang; BL Langdahl; LJ Launer; JY Lee; MM Lerch; JR Lewis; L Lind; C Lindgren; YM Liu; T Liu; YF Liu; O Ljunggren; M Lorentzon; RN Luben; W Maixner; FE McGuigan; Maria Medina Gomez; T Meitinger; H Melhus; D Mellstrom; S Melov; K Michaelsson; BD Mitchell; AP Morris; L Mosekilde; A Newman; CM Nielson; JR O'Connell; Ben Oostra; ES Orwoll; A Palotie; S Parker; M Peacock; M Perola; A Peters; O Polasek; RL Prince; K Raikkonen; SH Ralston; S Ripatti; JA Robbins; JI Rotter; I Rudan; V Salomaa; S Satterfield; EE Schadt; S Schipf; L Scott; J Sehmi; J Shen; CS Shin; G Sigurdsson; S Smith; N Soranzo; A Stancakova; E Steinhagen-Thiessen; EA Streeten; U Styrkarsdottir; KMA Swart; ST Tan; MA Tarnopolsky; P Thompson; CA Thomson; U Thorsteinsdottir; E Tikkanen; GJ Tranah; J Tuomilehto; NM Schoor; A Verma; P Vollenweider; H Volzke; J Wactawski-Wende; M Walker; MN Weedon; R Welch; HE Wichman; E Widen; FMK Williams; JF Wilson; NC Wright; WJ Xie; L Yu; YH Zhou; JC Chambers; A Doring; Cornelia Duijn; MJ Econs; V Gudnason; JS Kooner; BM Psaty; TD Spector; K Stefansson; Fernando Rivadeneira; André Uitterlinden; NJ Wareham; V Ossowski; D Waterworth; RJF Loos; D Karasik; TB Harris; C Ohlsson; DP Kiel

doi:10.1038/s41467-017-00031-7

Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

M.C. Zillikens, S Demissie, YH Hsu, LM Yerges-Armstrong, WC Chou, Lisette Stolk, G Livshits, Linda Broer, T Johnson, DL Koller, Z Kutalik, J Luan, I Malkin, JS Ried, AV Smith, G Thorleifsson, L Vandenput, JH Zhao, WH Zhang, A AghdassiK Akesson, Najaf Amin, LJ Baier, I Barroso, DA Bennett, L Bertram, R Biffar, M Bochud, M Boehnke, IB Borecki, AS Buchman, L Byberg, H Campbell, Natalia Campos Obando, JA Cauley, P M Cawthon, H Cederberg, Zhigang Chen, NH Cho, HJ Choi, M Claussnitzer, F Collins, SR Cummings, PL De Jager, I Demuth, RAM Dhonukshe-Rutten, L Diatchenko, G Eiriksdottir, Anke Enneman, M Erdos, JG Eriksson, J Eriksson, Karol Estrada Gil, DS Evans, MF Feitosa, M Fu, M Garcia, C Gieger, T Girke, NL Glazer, H Grallert, J Grewal, BG Han, RL Hanson, C Hayward, Bert Hofman, EP Hoffman, G Homuth, WC Hsueh, MJ Hubal, A Hubbard, KM Huffman, LB Husted, T Illig, E Ingelsson, T Ittermann, JO Jansson, JM Jordan, A Jula, M Karlsson, KT Khaw, TO Kilpainen, N Klopp, J Kloth, HA Koistinen, WE Kraus, S Kritchevsky, T Kuulasmaa, J Kuusisto, M Laakso, J Lahti, T Lang, BL Langdahl, LJ Launer, JY Lee, MM Lerch, JR Lewis, L Lind, C Lindgren, YM Liu, T Liu, YF Liu, O Ljunggren, M Lorentzon, RN Luben, W Maixner, FE McGuigan, Maria Medina Gomez, T Meitinger, H Melhus, D Mellstrom, S Melov, K Michaelsson, BD Mitchell, AP Morris, L Mosekilde, A Newman, CM Nielson, JR O'Connell, Ben Oostra, ES Orwoll, A Palotie, S Parker, M Peacock, M Perola, A Peters, O Polasek, RL Prince, K Raikkonen, SH Ralston, S Ripatti, JA Robbins, JI Rotter, I Rudan, V Salomaa, S Satterfield, EE Schadt, S Schipf, L Scott, J Sehmi, J Shen, CS Shin, G Sigurdsson, S Smith, N Soranzo, A Stancakova, E Steinhagen-Thiessen, EA Streeten, U Styrkarsdottir, KMA Swart, ST Tan, MA Tarnopolsky, P Thompson, CA Thomson, U Thorsteinsdottir, E Tikkanen, GJ Tranah, J Tuomilehto, NM Schoor, A Verma, P Vollenweider, H Volzke, J Wactawski-Wende, M Walker, MN Weedon, R Welch, HE Wichman, E Widen, FMK Williams, JF Wilson, NC Wright, WJ Xie, L Yu, YH Zhou, JC Chambers, A Doring, Cornelia Duijn, MJ Econs, V Gudnason, JS Kooner, BM Psaty, TD Spector, K Stefansson, Fernando Rivadeneira, André Uitterlinden, NJ Wareham, V Ossowski, D Waterworth, RJF Loos, D Karasik, TB Harris, C Ohlsson, DP Kiel

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Original language	Undefined/Unknown
Article number	80
Journal	Nature Communications
Volume	8
DOIs	https://doi.org/10.1038/s41467-017-00031-7
Publication status	Published - 2017

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Cite this

Zillikens, M. C., Demissie, S., Hsu, YH., Yerges-Armstrong, LM., Chou, WC., Stolk, L., Livshits, G., Broer, L., Johnson, T., Koller, DL., Kutalik, Z., Luan, J., Malkin, I., Ried, JS., Smith, AV., Thorleifsson, G., Vandenput, L., Zhao, JH., Zhang, WH., ... Kiel, DP. (2017). Large meta-analysis of genome-wide association studies identifies five loci for lean body mass. Nature Communications, 8, Article 80. https://doi.org/10.1038/s41467-017-00031-7

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author = "M.C. Zillikens and S Demissie and YH Hsu and LM Yerges-Armstrong and WC Chou and Lisette Stolk and G Livshits and Linda Broer and T Johnson and DL Koller and Z Kutalik and J Luan and I Malkin and JS Ried and AV Smith and G Thorleifsson and L Vandenput and JH Zhao and WH Zhang and A Aghdassi and K Akesson and Najaf Amin and LJ Baier and I Barroso and DA Bennett and L Bertram and R Biffar and M Bochud and M Boehnke and IB Borecki and AS Buchman and L Byberg and H Campbell and {Campos Obando}, Natalia and JA Cauley and Cawthon, {P M} and H Cederberg and Zhigang Chen and NH Cho and HJ Choi and M Claussnitzer and F Collins and SR Cummings and {De Jager}, PL and I Demuth and RAM Dhonukshe-Rutten and L Diatchenko and G Eiriksdottir and Anke Enneman and M Erdos and JG Eriksson and J Eriksson and {Estrada Gil}, Karol and DS Evans and MF Feitosa and M Fu and M Garcia and C Gieger and T Girke and NL Glazer and H Grallert and J Grewal and BG Han and RL Hanson and C Hayward and Bert Hofman and EP Hoffman and G Homuth and WC Hsueh and MJ Hubal and A Hubbard and KM Huffman and LB Husted and T Illig and E Ingelsson and T Ittermann and JO Jansson and JM Jordan and A Jula and M Karlsson and KT Khaw and TO Kilpainen and N Klopp and J Kloth and HA Koistinen and WE Kraus and S Kritchevsky and T Kuulasmaa and J Kuusisto and M Laakso and J Lahti and T Lang and BL Langdahl and LJ Launer and JY Lee and MM Lerch and JR Lewis and L Lind and C Lindgren and YM Liu and T Liu and YF Liu and O Ljunggren and M Lorentzon and RN Luben and W Maixner and FE McGuigan and {Medina Gomez}, Maria and T Meitinger and H Melhus and D Mellstrom and S Melov and K Michaelsson and BD Mitchell and AP Morris and L Mosekilde and A Newman and CM Nielson and JR O'Connell and Ben Oostra and ES Orwoll and A Palotie and S Parker and M Peacock and M Perola and A Peters and O Polasek and RL Prince and K Raikkonen and SH Ralston and S Ripatti and JA Robbins and JI Rotter and I Rudan and V Salomaa and S Satterfield and EE Schadt and S Schipf and L Scott and J Sehmi and J Shen and CS Shin and G Sigurdsson and S Smith and N Soranzo and A Stancakova and E Steinhagen-Thiessen and EA Streeten and U Styrkarsdottir and KMA Swart and ST Tan and MA Tarnopolsky and P Thompson and CA Thomson and U Thorsteinsdottir and E Tikkanen and GJ Tranah and J Tuomilehto and NM Schoor and A Verma and P Vollenweider and H Volzke and J Wactawski-Wende and M Walker and MN Weedon and R Welch and HE Wichman and E Widen and FMK Williams and JF Wilson and NC Wright and WJ Xie and L Yu and YH Zhou and JC Chambers and A Doring and Cornelia Duijn and MJ Econs and V Gudnason and JS Kooner and BM Psaty and TD Spector and K Stefansson and Fernando Rivadeneira and Andr{\'e} Uitterlinden and NJ Wareham and V Ossowski and D Waterworth and RJF Loos and D Karasik and TB Harris and C Ohlsson and DP Kiel",

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doi = "10.1038/s41467-017-00031-7",

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volume = "8",

journal = "Nature Communications",

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Zillikens, MC, Demissie, S, Hsu, YH, Yerges-Armstrong, LM, Chou, WC, Stolk, L, Livshits, G, Broer, L, Johnson, T, Koller, DL, Kutalik, Z, Luan, J, Malkin, I, Ried, JS, Smith, AV, Thorleifsson, G, Vandenput, L, Zhao, JH, Zhang, WH, Aghdassi, A, Akesson, K, Amin, N, Baier, LJ, Barroso, I, Bennett, DA, Bertram, L, Biffar, R, Bochud, M, Boehnke, M, Borecki, IB, Buchman, AS, Byberg, L, Campbell, H, Campos Obando, N, Cauley, JA, Cawthon, PM, Cederberg, H, Chen, Z, Cho, NH, Choi, HJ, Claussnitzer, M, Collins, F, Cummings, SR, De Jager, PL, Demuth, I, Dhonukshe-Rutten, RAM, Diatchenko, L, Eiriksdottir, G, Enneman, A, Erdos, M, Eriksson, JG, Eriksson, J, Estrada Gil, K, Evans, DS, Feitosa, MF, Fu, M, Garcia, M, Gieger, C, Girke, T, Glazer, NL, Grallert, H, Grewal, J, Han, BG, Hanson, RL, Hayward, C, Hofman, B, Hoffman, EP, Homuth, G, Hsueh, WC, Hubal, MJ, Hubbard, A, Huffman, KM, Husted, LB, Illig, T, Ingelsson, E, Ittermann, T, Jansson, JO, Jordan, JM, Jula, A, Karlsson, M, Khaw, KT, Kilpainen, TO, Klopp, N, Kloth, J, Koistinen, HA, Kraus, WE, Kritchevsky, S, Kuulasmaa, T, Kuusisto, J, Laakso, M, Lahti, J, Lang, T, Langdahl, BL, Launer, LJ, Lee, JY, Lerch, MM, Lewis, JR, Lind, L, Lindgren, C, Liu, YM, Liu, T, Liu, YF, Ljunggren, O, Lorentzon, M, Luben, RN, Maixner, W, McGuigan, FE, Medina Gomez, M, Meitinger, T, Melhus, H, Mellstrom, D, Melov, S, Michaelsson, K, Mitchell, BD, Morris, AP, Mosekilde, L, Newman, A, Nielson, CM, O'Connell, JR, Oostra, B, Orwoll, ES, Palotie, A, Parker, S, Peacock, M, Perola, M, Peters, A, Polasek, O, Prince, RL, Raikkonen, K, Ralston, SH, Ripatti, S, Robbins, JA, Rotter, JI, Rudan, I, Salomaa, V, Satterfield, S, Schadt, EE, Schipf, S, Scott, L, Sehmi, J, Shen, J, Shin, CS, Sigurdsson, G, Smith, S, Soranzo, N, Stancakova, A, Steinhagen-Thiessen, E, Streeten, EA, Styrkarsdottir, U, Swart, KMA, Tan, ST, Tarnopolsky, MA, Thompson, P, Thomson, CA, Thorsteinsdottir, U, Tikkanen, E, Tranah, GJ, Tuomilehto, J, Schoor, NM, Verma, A, Vollenweider, P, Volzke, H, Wactawski-Wende, J, Walker, M, Weedon, MN, Welch, R, Wichman, HE, Widen, E, Williams, FMK, Wilson, JF, Wright, NC, Xie, WJ, Yu, L, Zhou, YH, Chambers, JC, Doring, A, Duijn, C, Econs, MJ, Gudnason, V, Kooner, JS, Psaty, BM, Spector, TD, Stefansson, K, Rivadeneira, F , Uitterlinden, A, Wareham, NJ, Ossowski, V, Waterworth, D, Loos, RJF, Karasik, D, Harris, TB, Ohlsson, C & Kiel, DP 2017, 'Large meta-analysis of genome-wide association studies identifies five loci for lean body mass', Nature Communications, vol. 8, 80. https://doi.org/10.1038/s41467-017-00031-7

TY - JOUR

T1 - Large meta-analysis of genome-wide association studies identifies five loci for lean body mass

AU - Zillikens, M.C.

AU - Demissie, S

AU - Hsu, YH

AU - Yerges-Armstrong, LM

AU - Chou, WC

AU - Stolk, Lisette

AU - Livshits, G

AU - Broer, Linda

AU - Johnson, T

AU - Koller, DL

AU - Kutalik, Z

AU - Luan, J

AU - Malkin, I

AU - Ried, JS

AU - Smith, AV

AU - Thorleifsson, G

AU - Vandenput, L

AU - Zhao, JH

AU - Zhang, WH

AU - Aghdassi, A

AU - Akesson, K

AU - Amin, Najaf

AU - Baier, LJ

AU - Barroso, I

AU - Bennett, DA

AU - Bertram, L

AU - Biffar, R

AU - Bochud, M

AU - Boehnke, M

AU - Borecki, IB

AU - Buchman, AS

AU - Byberg, L

AU - Campbell, H

AU - Campos Obando, Natalia

AU - Cauley, JA

AU - Cawthon, P M

AU - Cederberg, H

AU - Chen, Zhigang

AU - Cho, NH

AU - Choi, HJ

AU - Claussnitzer, M

AU - Collins, F

AU - Cummings, SR

AU - De Jager, PL

AU - Demuth, I

AU - Dhonukshe-Rutten, RAM

AU - Diatchenko, L

AU - Eiriksdottir, G

AU - Enneman, Anke

AU - Erdos, M

AU - Eriksson, JG

AU - Eriksson, J

AU - Estrada Gil, Karol

AU - Evans, DS

AU - Feitosa, MF

AU - Fu, M

AU - Garcia, M

AU - Gieger, C

AU - Girke, T

AU - Glazer, NL

AU - Grallert, H

AU - Grewal, J

AU - Han, BG

AU - Hanson, RL

AU - Hayward, C

AU - Hofman, Bert

AU - Hoffman, EP

AU - Homuth, G

AU - Hsueh, WC

AU - Hubal, MJ

AU - Hubbard, A

AU - Huffman, KM

AU - Husted, LB

AU - Illig, T

AU - Ingelsson, E

AU - Ittermann, T

AU - Jansson, JO

AU - Jordan, JM

AU - Jula, A

AU - Karlsson, M

AU - Khaw, KT

AU - Kilpainen, TO

AU - Klopp, N

AU - Kloth, J

AU - Koistinen, HA

AU - Kraus, WE

AU - Kritchevsky, S

AU - Kuulasmaa, T

AU - Kuusisto, J

AU - Laakso, M

AU - Lahti, J

AU - Lang, T

AU - Langdahl, BL

AU - Launer, LJ

AU - Lee, JY

AU - Lerch, MM

AU - Lewis, JR

AU - Lind, L

AU - Lindgren, C

AU - Liu, YM

AU - Liu, T

AU - Liu, YF

AU - Ljunggren, O

AU - Lorentzon, M

AU - Luben, RN

AU - Maixner, W

AU - McGuigan, FE

AU - Medina Gomez, Maria

AU - Meitinger, T

AU - Melhus, H

AU - Mellstrom, D

AU - Melov, S

AU - Michaelsson, K

AU - Mitchell, BD

AU - Morris, AP

AU - Mosekilde, L

AU - Newman, A

AU - Nielson, CM

AU - O'Connell, JR

AU - Oostra, Ben

AU - Orwoll, ES

AU - Palotie, A

AU - Parker, S

AU - Peacock, M

AU - Perola, M

AU - Peters, A

AU - Polasek, O

AU - Prince, RL

AU - Raikkonen, K

AU - Ralston, SH

AU - Ripatti, S

AU - Robbins, JA

AU - Rotter, JI

AU - Rudan, I

AU - Salomaa, V

AU - Satterfield, S

AU - Schadt, EE

AU - Schipf, S

AU - Scott, L

AU - Sehmi, J

AU - Shen, J

AU - Shin, CS

AU - Sigurdsson, G

AU - Smith, S

AU - Soranzo, N

AU - Stancakova, A

AU - Steinhagen-Thiessen, E

AU - Streeten, EA

AU - Styrkarsdottir, U

AU - Swart, KMA

AU - Tan, ST

AU - Tarnopolsky, MA

AU - Thompson, P

AU - Thomson, CA

AU - Thorsteinsdottir, U

AU - Tikkanen, E

AU - Tranah, GJ

AU - Tuomilehto, J

AU - Schoor, NM

AU - Verma, A

AU - Vollenweider, P

AU - Volzke, H

AU - Wactawski-Wende, J

AU - Walker, M

AU - Weedon, MN

AU - Welch, R

AU - Wichman, HE

AU - Widen, E

AU - Williams, FMK

AU - Wilson, JF

AU - Wright, NC

AU - Xie, WJ

AU - Yu, L

AU - Zhou, YH

AU - Chambers, JC

AU - Doring, A

AU - Duijn, Cornelia

AU - Econs, MJ

AU - Gudnason, V

AU - Kooner, JS

AU - Psaty, BM

AU - Spector, TD

AU - Stefansson, K

AU - Rivadeneira, Fernando

AU - Uitterlinden, André

AU - Wareham, NJ

AU - Ossowski, V

AU - Waterworth, D

AU - Loos, RJF

AU - Karasik, D

AU - Harris, TB

AU - Ohlsson, C

AU - Kiel, DP

PY - 2017

Y1 - 2017

U2 - 10.1038/s41467-017-00031-7

DO - 10.1038/s41467-017-00031-7

M3 - Article

C2 - 28724990

SN - 2041-1723

VL - 8

JO - Nature Communications

JF - Nature Communications

M1 - 80

ER -