Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

PS Wild; Janine Felix; A Schillert; A Teumer; MH Chen; Maarten Leening; U Volker; V Grossmann; JA Brody; M R Irvin; SJ Shah; S Pramana; W Lieb; R Schmidt; AV Stanton; D Malzahn; AV Smith; J Sundstrom; C Minelli; D Ruggiero; LP Lyytikainen; D Tiller; JG Smith; Claire Monnereau; MR Di Tullio; SK Musani; AC Morrison; TH Pers; M Morley; ME Kleber; J Aragam; EJ Benjamin; JC Bis; E Bisping; U Broeckel; S Cheng; Jaap Deckers; MF Del Greco; F Edelmann; M Fornage; L Franke; N Friedrich; TB Harris; E Hofer; Bert Hofman; J Huang; AD Hughes; M Kahonen; J Kruppa; KJ Lackner; L Lannfelt; R Laskowski; LJ Launer; M Leosdottir; HH Lin; CM Lindgren; C Loley; CA MacRae; D Mascalzoni; J Mayet; D Medenwald; AP Morris; C Muller; M Muller-Nurasyid; S Nappo; PM Nilsson; S Nuding; T Nutile; A Peters; A Pfeufer; D Pietzner; PP Pramstaller; OT Raitakari; KM Rice; Fernando Rivadeneira; JI Rotter; ST Ruohonen; RL Sacco; TE Samdarshi; H Schmidt; ASP Sharp; DC Shields; R Sorice; N Sotoodehnia; Bruno Stricker; P Surendran; S Thom; AM Toglhofer; André Uitterlinden; R Wachter; H Volzke; A Ziegler; T Munzel; W Marz; TP Cappola; JN Hirschhorn; GF Mitchell; NL Smith; ER Fox; ND Dueker; Vincent Jaddoe; O Melander; M Russ; T Lehtimaki; M Ciullo; AA Hicks; L Lind; V Gudnason; B Pieske; AJ Barron; R Zweiker; H Schunkert; E Ingelsson; KY Liu; DK Arnett; BM Psaty; S Blankenberg; MG Larson; SB Felix; OH Franco Duran; T Zeller; RS Vasan; M Dorr

doi:10.1172/jci84840

Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

PS Wild
, Janine Felix
, A Schillert
, A Teumer
, MH Chen
, Maarten Leening
, U Volker
, V Grossmann
, JA Brody
, M R Irvin
, SJ Shah
, S Pramana
, W Lieb
, R Schmidt
, AV Stanton
, D Malzahn
, AV Smith
, J Sundstrom
, C Minelli
, D Ruggiero

LP Lyytikainen, D Tiller, JG Smith, Claire Monnereau, MR Di Tullio, SK Musani, AC Morrison, TH Pers, M Morley, ME Kleber, J Aragam, EJ Benjamin, JC Bis, E Bisping, U Broeckel, S Cheng, Jaap Deckers, MF Del Greco, F Edelmann, M Fornage, L Franke, N Friedrich, TB Harris, E Hofer, Bert Hofman, J Huang, AD Hughes, M Kahonen, J Kruppa, KJ Lackner, L Lannfelt, R Laskowski, LJ Launer, M Leosdottir, HH Lin, CM Lindgren, C Loley, CA MacRae, D Mascalzoni, J Mayet, D Medenwald, AP Morris, C Muller, M Muller-Nurasyid, S Nappo, PM Nilsson, S Nuding, T Nutile, A Peters, A Pfeufer, D Pietzner, PP Pramstaller, OT Raitakari, KM Rice, Fernando Rivadeneira, JI Rotter, ST Ruohonen, RL Sacco, TE Samdarshi, H Schmidt, ASP Sharp, DC Shields, R Sorice, N Sotoodehnia, Bruno Stricker, P Surendran, S Thom, AM Toglhofer, André Uitterlinden, R Wachter, H Volzke, A Ziegler, T Munzel, W Marz, TP Cappola, JN Hirschhorn, GF Mitchell, NL Smith, ER Fox, ND Dueker, Vincent Jaddoe, O Melander, M Russ, T Lehtimaki, M Ciullo, AA Hicks, L Lind, V Gudnason, B Pieske, AJ Barron, R Zweiker, H Schunkert, E Ingelsson, KY Liu, DK Arnett, BM Psaty, S Blankenberg, MG Larson, SB Felix, OH Franco Duran, T Zeller, RS Vasan, M Dorr

External organisation

Research output: Contribution to journal › Article › Academic › peer-review

102 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	1798-1812
Number of pages	15
Journal	Journal of Clinical Investigation
Volume	127
Issue number	5
DOIs	https://doi.org/10.1172/jci84840
Publication status	Published - 2017

Research programs

EMC COEUR-09
EMC MM-04-54-08-A

Access to Document

10.1172/jci84840

http://hdl.handle.net/1765/99808

Cite this

Wild, PS., Felix, J., Schillert, A., Teumer, A., Chen, MH., Leening, M., Volker, U., Grossmann, V., Brody, JA., Irvin, M. R., Shah, SJ., Pramana, S., Lieb, W., Schmidt, R., Stanton, AV., Malzahn, D., Smith, AV., Sundstrom, J., Minelli, C., ... Dorr, M. (2017). Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function. Journal of Clinical Investigation, 127(5), 1798-1812. https://doi.org/10.1172/jci84840

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author = "PS Wild and Janine Felix and A Schillert and A Teumer and MH Chen and Maarten Leening and U Volker and V Grossmann and JA Brody and Irvin, \{M R\} and SJ Shah and S Pramana and W Lieb and R Schmidt and AV Stanton and D Malzahn and AV Smith and J Sundstrom and C Minelli and D Ruggiero and LP Lyytikainen and D Tiller and JG Smith and Claire Monnereau and \{Di Tullio\}, MR and SK Musani and AC Morrison and TH Pers and M Morley and ME Kleber and J Aragam and EJ Benjamin and JC Bis and E Bisping and U Broeckel and S Cheng and Jaap Deckers and \{Del Greco\}, MF and F Edelmann and M Fornage and L Franke and N Friedrich and TB Harris and E Hofer and Bert Hofman and J Huang and AD Hughes and M Kahonen and J Kruppa and KJ Lackner and L Lannfelt and R Laskowski and LJ Launer and M Leosdottir and HH Lin and CM Lindgren and C Loley and CA MacRae and D Mascalzoni and J Mayet and D Medenwald and AP Morris and C Muller and M Muller-Nurasyid and S Nappo and PM Nilsson and S Nuding and T Nutile and A Peters and A Pfeufer and D Pietzner and PP Pramstaller and OT Raitakari and KM Rice and Fernando Rivadeneira and JI Rotter and ST Ruohonen and RL Sacco and TE Samdarshi and H Schmidt and ASP Sharp and DC Shields and R Sorice and N Sotoodehnia and Bruno Stricker and P Surendran and S Thom and AM Toglhofer and Andr{\'e} Uitterlinden and R Wachter and H Volzke and A Ziegler and T Munzel and W Marz and TP Cappola and JN Hirschhorn and GF Mitchell and NL Smith and ER Fox and ND Dueker and Vincent Jaddoe and O Melander and M Russ and T Lehtimaki and M Ciullo and AA Hicks and L Lind and V Gudnason and B Pieske and AJ Barron and R Zweiker and H Schunkert and E Ingelsson and KY Liu and DK Arnett and BM Psaty and S Blankenberg and MG Larson and SB Felix and \{Franco Duran\}, OH and T Zeller and RS Vasan and M Dorr",

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doi = "10.1172/jci84840",

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pages = "1798--1812",

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Wild, PS, Felix, J, Schillert, A, Teumer, A, Chen, MH, Leening, M, Volker, U, Grossmann, V, Brody, JA, Irvin, MR, Shah, SJ, Pramana, S, Lieb, W, Schmidt, R, Stanton, AV, Malzahn, D, Smith, AV, Sundstrom, J, Minelli, C, Ruggiero, D, Lyytikainen, LP, Tiller, D, Smith, JG, Monnereau, C, Di Tullio, MR, Musani, SK, Morrison, AC, Pers, TH, Morley, M, Kleber, ME, Aragam, J, Benjamin, EJ, Bis, JC, Bisping, E, Broeckel, U, Cheng, S, Deckers, J, Del Greco, MF, Edelmann, F, Fornage, M, Franke, L, Friedrich, N, Harris, TB, Hofer, E, Hofman, B, Huang, J, Hughes, AD, Kahonen, M, Kruppa, J, Lackner, KJ, Lannfelt, L, Laskowski, R, Launer, LJ, Leosdottir, M, Lin, HH, Lindgren, CM, Loley, C, MacRae, CA, Mascalzoni, D, Mayet, J, Medenwald, D, Morris, AP, Muller, C, Muller-Nurasyid, M, Nappo, S, Nilsson, PM, Nuding, S, Nutile, T, Peters, A, Pfeufer, A, Pietzner, D, Pramstaller, PP, Raitakari, OT, Rice, KM, Rivadeneira, F, Rotter, JI, Ruohonen, ST, Sacco, RL, Samdarshi, TE, Schmidt, H, Sharp, ASP, Shields, DC, Sorice, R, Sotoodehnia, N, Stricker, B, Surendran, P, Thom, S, Toglhofer, AM, Uitterlinden, A, Wachter, R, Volzke, H, Ziegler, A, Munzel, T, Marz, W, Cappola, TP, Hirschhorn, JN, Mitchell, GF, Smith, NL, Fox, ER, Dueker, ND, Jaddoe, V, Melander, O, Russ, M, Lehtimaki, T, Ciullo, M, Hicks, AA, Lind, L, Gudnason, V, Pieske, B, Barron, AJ, Zweiker, R, Schunkert, H, Ingelsson, E, Liu, KY, Arnett, DK, Psaty, BM, Blankenberg, S, Larson, MG, Felix, SB, Franco Duran, OH, Zeller, T, Vasan, RS & Dorr, M 2017, 'Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function', Journal of Clinical Investigation, vol. 127, no. 5, pp. 1798-1812. https://doi.org/10.1172/jci84840

TY - JOUR

T1 - Large-scale genome-wide analysis identifies genetic variants associated with cardiac structure and function

AU - Wild, PS

AU - Felix, Janine

AU - Schillert, A

AU - Teumer, A

AU - Chen, MH

AU - Leening, Maarten

AU - Volker, U

AU - Grossmann, V

AU - Brody, JA

AU - Irvin, M R

AU - Shah, SJ

AU - Pramana, S

AU - Lieb, W

AU - Schmidt, R

AU - Stanton, AV

AU - Malzahn, D

AU - Smith, AV

AU - Sundstrom, J

AU - Minelli, C

AU - Ruggiero, D

AU - Lyytikainen, LP

AU - Tiller, D

AU - Smith, JG

AU - Monnereau, Claire

AU - Di Tullio, MR

AU - Musani, SK

AU - Morrison, AC

AU - Pers, TH

AU - Morley, M

AU - Kleber, ME

AU - Aragam, J

AU - Benjamin, EJ

AU - Bis, JC

AU - Bisping, E

AU - Broeckel, U

AU - Cheng, S

AU - Deckers, Jaap

AU - Del Greco, MF

AU - Edelmann, F

AU - Fornage, M

AU - Franke, L

AU - Friedrich, N

AU - Harris, TB

AU - Hofer, E

AU - Hofman, Bert

AU - Huang, J

AU - Hughes, AD

AU - Kahonen, M

AU - Kruppa, J

AU - Lackner, KJ

AU - Lannfelt, L

AU - Laskowski, R

AU - Launer, LJ

AU - Leosdottir, M

AU - Lin, HH

AU - Lindgren, CM

AU - Loley, C

AU - MacRae, CA

AU - Mascalzoni, D

AU - Mayet, J

AU - Medenwald, D

AU - Morris, AP

AU - Muller, C

AU - Muller-Nurasyid, M

AU - Nappo, S

AU - Nilsson, PM

AU - Nuding, S

AU - Nutile, T

AU - Peters, A

AU - Pfeufer, A

AU - Pietzner, D

AU - Pramstaller, PP

AU - Raitakari, OT

AU - Rice, KM

AU - Rivadeneira, Fernando

AU - Rotter, JI

AU - Ruohonen, ST

AU - Sacco, RL

AU - Samdarshi, TE

AU - Schmidt, H

AU - Sharp, ASP

AU - Shields, DC

AU - Sorice, R

AU - Sotoodehnia, N

AU - Stricker, Bruno

AU - Surendran, P

AU - Thom, S

AU - Toglhofer, AM

AU - Uitterlinden, André

AU - Wachter, R

AU - Volzke, H

AU - Ziegler, A

AU - Munzel, T

AU - Marz, W

AU - Cappola, TP

AU - Hirschhorn, JN

AU - Mitchell, GF

AU - Smith, NL

AU - Fox, ER

AU - Dueker, ND

AU - Jaddoe, Vincent

AU - Melander, O

AU - Russ, M

AU - Lehtimaki, T

AU - Ciullo, M

AU - Hicks, AA

AU - Lind, L

AU - Gudnason, V

AU - Pieske, B

AU - Barron, AJ

AU - Zweiker, R

AU - Schunkert, H

AU - Ingelsson, E

AU - Liu, KY

AU - Arnett, DK

AU - Psaty, BM

AU - Blankenberg, S

AU - Larson, MG

AU - Felix, SB

AU - Franco Duran, OH

AU - Zeller, T

AU - Vasan, RS

AU - Dorr, M

PY - 2017

Y1 - 2017

U2 - 10.1172/jci84840

DO - 10.1172/jci84840

M3 - Article

SN - 0021-9738

VL - 127

SP - 1798

EP - 1812

JO - Journal of Clinical Investigation

JF - Journal of Clinical Investigation

IS - 5

ER -