Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

SM Willems; DJ Wright; FR Day; Katerina Trajanoska; PK Joshi; JA Morris; A M Matteini; FC Garton; N Grarup; N Oskolkov; A Thalamuthu; M Mangino; Jun Liu; Ayse Demirkan; M Lek; LW Xu; G Wang; C Oldmeadow; KJ Gaulton; LA Lotta; E Miyamoto-Mikami; MA Rivas; T White; PR Loh; M Aadahl; Najaf Amin; JR Attia; K Austin; B Benyamin; S Brage; YC Cheng; P Cieszczyk; W Derave; KF Eriksson; N Eynon; A Linneberg; A Lucia; M Massidda; BD Mitchell; M Miyachi; H Murakami; S Padmanabhan; A Pandey; L Papadimitriou; DK Rajpal; C Sale; TM Schnurr; F Sessa; N Shrine; MD Tobin; I Varley; LV Wain; NR Wray; CM Lindgren; DG MacArthur; DM Waterworth; MI McCarthy; O Pedersen; KT Khaw; DP Kie; Y Pitsiladis; N Fuku; PW Franks; KN North; Cornelia Duijn; KA Mather; T Hansen; O Hansson; T Spector; JM Murabito; JB Richards; Fernando Rivadeneira; C Langenberg; JRB Perry; NJ Wareham; RA Scott

doi:10.1038/ncomms16015

Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

SM Willems
, DJ Wright
, FR Day
, Katerina Trajanoska
, PK Joshi
, JA Morris
, A M Matteini
, FC Garton
, N Grarup
, N Oskolkov
, A Thalamuthu
, M Mangino
, Jun Liu
, Ayse Demirkan
, M Lek
, LW Xu
, G Wang
, C Oldmeadow
, KJ Gaulton
, LA Lotta

E Miyamoto-Mikami, MA Rivas, T White, PR Loh, M Aadahl, Najaf Amin, JR Attia, K Austin, B Benyamin, S Brage, YC Cheng, P Cieszczyk, W Derave, KF Eriksson, N Eynon, A Linneberg, A Lucia, M Massidda, BD Mitchell, M Miyachi, H Murakami, S Padmanabhan, A Pandey, L Papadimitriou, DK Rajpal, C Sale, TM Schnurr, F Sessa, N Shrine, MD Tobin, I Varley, LV Wain, NR Wray, CM Lindgren, DG MacArthur, DM Waterworth, MI McCarthy, O Pedersen, KT Khaw, DP Kie, Y Pitsiladis, N Fuku, PW Franks, KN North, Cornelia Duijn, KA Mather, T Hansen, O Hansson, T Spector, JM Murabito, JB Richards, Fernando Rivadeneira, C Langenberg, JRB Perry, NJ Wareham, RA Scott

Research output: Contribution to journal › Article › Academic › peer-review

186 Citations (Scopus)

120 Downloads (Pure)

Original language	Undefined/Unknown
Article number	16015
Journal	Nature Communications
Volume	8
DOIs	https://doi.org/10.1038/ncomms16015
Publication status	Published - 2017

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EMC OR-01

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10.1038/ncomms16015

ncomms16015.pdfFinal published version, 442 KB

http://hdl.handle.net/1765/100892

Cite this

Willems, SM., Wright, DJ., Day, FR., Trajanoska, K., Joshi, PK., Morris, JA., Matteini, A. M., Garton, FC., Grarup, N., Oskolkov, N., Thalamuthu, A., Mangino, M., Liu, J., Demirkan, A., Lek, M., Xu, LW., Wang, G., Oldmeadow, C., Gaulton, KJ., ... Scott, RA. (2017). Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness. Nature Communications, 8, Article 16015. https://doi.org/10.1038/ncomms16015

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title = "Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness",

author = "SM Willems and DJ Wright and FR Day and Katerina Trajanoska and PK Joshi and JA Morris and Matteini, \{A M\} and FC Garton and N Grarup and N Oskolkov and A Thalamuthu and M Mangino and Jun Liu and Ayse Demirkan and M Lek and LW Xu and G Wang and C Oldmeadow and KJ Gaulton and LA Lotta and E Miyamoto-Mikami and MA Rivas and T White and PR Loh and M Aadahl and Najaf Amin and JR Attia and K Austin and B Benyamin and S Brage and YC Cheng and P Cieszczyk and W Derave and KF Eriksson and N Eynon and A Linneberg and A Lucia and M Massidda and BD Mitchell and M Miyachi and H Murakami and S Padmanabhan and A Pandey and L Papadimitriou and DK Rajpal and C Sale and TM Schnurr and F Sessa and N Shrine and MD Tobin and I Varley and LV Wain and NR Wray and CM Lindgren and DG MacArthur and DM Waterworth and MI McCarthy and O Pedersen and KT Khaw and DP Kie and Y Pitsiladis and N Fuku and PW Franks and KN North and Cornelia Duijn and KA Mather and T Hansen and O Hansson and T Spector and JM Murabito and JB Richards and Fernando Rivadeneira and C Langenberg and JRB Perry and NJ Wareham and RA Scott",

year = "2017",

doi = "10.1038/ncomms16015",

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Willems, SM, Wright, DJ, Day, FR, Trajanoska, K, Joshi, PK, Morris, JA, Matteini, AM, Garton, FC, Grarup, N, Oskolkov, N, Thalamuthu, A, Mangino, M, Liu, J, Demirkan, A, Lek, M, Xu, LW, Wang, G, Oldmeadow, C, Gaulton, KJ, Lotta, LA, Miyamoto-Mikami, E, Rivas, MA, White, T, Loh, PR, Aadahl, M, Amin, N, Attia, JR, Austin, K, Benyamin, B, Brage, S, Cheng, YC, Cieszczyk, P, Derave, W, Eriksson, KF, Eynon, N, Linneberg, A, Lucia, A, Massidda, M, Mitchell, BD, Miyachi, M, Murakami, H, Padmanabhan, S, Pandey, A, Papadimitriou, L, Rajpal, DK, Sale, C, Schnurr, TM, Sessa, F, Shrine, N, Tobin, MD, Varley, I, Wain, LV, Wray, NR, Lindgren, CM, MacArthur, DG, Waterworth, DM, McCarthy, MI, Pedersen, O, Khaw, KT, Kie, DP, Pitsiladis, Y, Fuku, N, Franks, PW, North, KN, Duijn, C, Mather, KA, Hansen, T, Hansson, O, Spector, T, Murabito, JM, Richards, JB, Rivadeneira, F, Langenberg, C, Perry, JRB, Wareham, NJ & Scott, RA 2017, 'Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness', Nature Communications, vol. 8, 16015. https://doi.org/10.1038/ncomms16015

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T1 - Large-scale GWAS identifies multiple loci for hand grip strength providing biological insights into muscular fitness

AU - Willems, SM

AU - Wright, DJ

AU - Day, FR

AU - Trajanoska, Katerina

AU - Joshi, PK

AU - Morris, JA

AU - Matteini, A M

AU - Garton, FC

AU - Grarup, N

AU - Oskolkov, N

AU - Thalamuthu, A

AU - Mangino, M

AU - Liu, Jun

AU - Demirkan, Ayse

AU - Lek, M

AU - Xu, LW

AU - Wang, G

AU - Oldmeadow, C

AU - Gaulton, KJ

AU - Lotta, LA

AU - Miyamoto-Mikami, E

AU - Rivas, MA

AU - White, T

AU - Loh, PR

AU - Aadahl, M

AU - Amin, Najaf

AU - Attia, JR

AU - Austin, K

AU - Benyamin, B

AU - Brage, S

AU - Cheng, YC

AU - Cieszczyk, P

AU - Derave, W

AU - Eriksson, KF

AU - Eynon, N

AU - Linneberg, A

AU - Lucia, A

AU - Massidda, M

AU - Mitchell, BD

AU - Miyachi, M

AU - Murakami, H

AU - Padmanabhan, S

AU - Pandey, A

AU - Papadimitriou, L

AU - Rajpal, DK

AU - Sale, C

AU - Schnurr, TM

AU - Sessa, F

AU - Shrine, N

AU - Tobin, MD

AU - Varley, I

AU - Wain, LV

AU - Wray, NR

AU - Lindgren, CM

AU - MacArthur, DG

AU - Waterworth, DM

AU - McCarthy, MI

AU - Pedersen, O

AU - Khaw, KT

AU - Kie, DP

AU - Pitsiladis, Y

AU - Fuku, N

AU - Franks, PW

AU - North, KN

AU - Duijn, Cornelia

AU - Mather, KA

AU - Hansen, T

AU - Hansson, O

AU - Spector, T

AU - Murabito, JM

AU - Richards, JB

AU - Rivadeneira, Fernando

AU - Langenberg, C

AU - Perry, JRB

AU - Wareham, NJ

AU - Scott, RA

PY - 2017

Y1 - 2017

U2 - 10.1038/ncomms16015

DO - 10.1038/ncomms16015

M3 - Article

C2 - 29313844

SN - 2041-1723

VL - 8

JO - Nature Communications

JF - Nature Communications

M1 - 16015

ER -