Late Breaking Abstract - Physical recovery and persistent fatigue up to 12 months after hospitalization for COVID-19

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Abstract

Data on the physical consequences and its recovery over time after hospitalization for COVID-19 are scarce. A factor that may influence physical function is persistent fatigue: a frequently reported complain after COVID-19. We described the trajectory of physical recovery up to 12 months and how persistent fatigue is related to physical function in hospitalized COVID-19 patients.

This ongoing prospective cohort study included COVID-19 survivors admitted to hospitals in the Netherlands. Study visits were performed at 3, 6, and 12 months post discharge. Patients performed the 6 minute walk test, 1 minute sit-to-stand (1MSTS), grip strength with handheld dynamometry, and a questionnaire on fatigue. Analyses were performed using linear mixed models.

In total, 435 patients had current data available: mean age 59.7±11.7 years, 287 (66.0%) males, and mean hospital stay 18.8±19.2 days. Six-minute walking distance improved from 477.8±7.1m to 502.7±7.3m to 520.2±9.2m at 3, 6, and 12 months respectively (P
Physical recovery was observed in COVID-19 patients up to 12 months after hospitalization. The majority of patients reported persistent fatigue up to 12 months. We found that higher levels of fatigue contribute to poorer physical function.
Original languageEnglish
Number of pages2
JournalEuropean Respiratory Journal
Volume58
DOIs
Publication statusPublished - 5 Sept 2021

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