TY - JOUR
T1 - Left ventricular remodelling and systolic function measurement with 64 multi-slice computed tomography versus second harmonic echocardiography in patients with coronary artery disease: A double blind study
AU - Palazzuoli, A
AU - Cademartiri, F.
AU - Geleijnse, Marcel
AU - Meijboom, B
AU - Pugliese, F
AU - Soliman, Osama
AU - Calabro, A
AU - Nuti, R
AU - Feijter, Pim
PY - 2010
Y1 - 2010
N2 - The present study evaluated LV volumes, ejection fraction (LVEF) and stroke volume (SV) obtained by 64-MDCT and to compare these data with those obtained by second harmonic 2D Echo, in patients referred for non-invasive coronary vessels evaluation. The most common technique in daily clinical practice used for determination of LV function is two-dimensional echocardiography (2D-TTE). Multi-detector computed tomography (MDCT) is an emerging new technique to detect coronary artery disease (CAD) and was recently proposed to assess LV function. 93 patients underwent to 64-MDCT for LV function and volumes assessment by segmental reconstruction algorithm (Argus) and compared with recent (2 months) 2D-TTE, all images were processed and interpreted by two observers blinded to the Echo and MDCT results. A close correlation between TTE and 64 MDCT was demonstrated for the ejection fraction LVEF (r = 0.84), end-diastolic volume LVEDV (r = 0.80) and end-systolic volume LVESV (r = 0.85); acceptable correlation was recruited for stroke volume LVSV (r = 0.58). Optimal results were recruited for inter-observer variability for 64-MDCT measured in 45 patients: LVESV (r = 0.82, p < 0.001), LVEDV (r = 0.83, p < 0.001), LVEF (r = 0.69, p < 0.002) and SV (r = 0.66, p < 0.001). Our results, showed that functional and temporal information contained in a coronary 64-MDCT study can be used to assess left ventricular (LV) systolic function and LV dimensions with good reproducibility and acceptable correlation respect to 2D-TTE. The combination of non-invasive coronary artery imaging and assessment of global LV function might became in the future a fast and conclusive cardiac work-up in patients with CAD. (C) 2008 Published by Elsevier Ireland Ltd.
AB - The present study evaluated LV volumes, ejection fraction (LVEF) and stroke volume (SV) obtained by 64-MDCT and to compare these data with those obtained by second harmonic 2D Echo, in patients referred for non-invasive coronary vessels evaluation. The most common technique in daily clinical practice used for determination of LV function is two-dimensional echocardiography (2D-TTE). Multi-detector computed tomography (MDCT) is an emerging new technique to detect coronary artery disease (CAD) and was recently proposed to assess LV function. 93 patients underwent to 64-MDCT for LV function and volumes assessment by segmental reconstruction algorithm (Argus) and compared with recent (2 months) 2D-TTE, all images were processed and interpreted by two observers blinded to the Echo and MDCT results. A close correlation between TTE and 64 MDCT was demonstrated for the ejection fraction LVEF (r = 0.84), end-diastolic volume LVEDV (r = 0.80) and end-systolic volume LVESV (r = 0.85); acceptable correlation was recruited for stroke volume LVSV (r = 0.58). Optimal results were recruited for inter-observer variability for 64-MDCT measured in 45 patients: LVESV (r = 0.82, p < 0.001), LVEDV (r = 0.83, p < 0.001), LVEF (r = 0.69, p < 0.002) and SV (r = 0.66, p < 0.001). Our results, showed that functional and temporal information contained in a coronary 64-MDCT study can be used to assess left ventricular (LV) systolic function and LV dimensions with good reproducibility and acceptable correlation respect to 2D-TTE. The combination of non-invasive coronary artery imaging and assessment of global LV function might became in the future a fast and conclusive cardiac work-up in patients with CAD. (C) 2008 Published by Elsevier Ireland Ltd.
U2 - 10.1016/j.ejrad.2008.09.022
DO - 10.1016/j.ejrad.2008.09.022
M3 - Article
C2 - 19013044
SN - 0720-048X
VL - 73
SP - 82
EP - 88
JO - European Journal of Radiology
JF - European Journal of Radiology
IS - 1
ER -