Skip to main navigation Skip to search Skip to main content

Liberation from invasive mechanical ventilation: A nationwide survey among intensive care units in the Netherlands

  • Franciscus Gasthuis & Vlietland
  • Erasmus University Medical Centre
  • Radboud University Medical Center
  • Onze Lieve Vrouwe Gasthuis

Research output: Contribution to journalArticleAcademicpeer-review

2 Citations (Scopus)
44 Downloads (Pure)

Abstract

Background:

Liberation from invasive mechanical ventilation is a milestone in critical care, but approaches vary. This survey aimed to describe current ventilator liberation practices, relate them to available evidence, and identify areas for improvement.

Methods:

A survey was performed among Dutch intensive care unit (ICU) sites. The survey evaluated practice in seven domains of ventilator liberation: protocol availability, transition from controlled to assisted ventilation, spontaneous breathing trials (SBT), cuff-leak test, postextubation support, weaning failure and tracheostomised weaning. 

Results: 

The survey response rate was 93% (132/142), representing 97% (69/71) of Dutch ICUs. Protocols for postextubation support and weaning failure were available in less than half of the ICUs (44% and 49%, respectively). The transition from controlled to assisted ventilation is regularly evaluated daily in 78% of ICUs. Assisted ventilation tolerance is mainly assessed by clinical signs, respiratory parameters and non-invasive manoeuvres that assess respiratory drive (P 0.1). SBTs are regularly performed in 58% of ICUs, using one or more of the following methods: T-piece (52%), pressure support+positive end expiratory pressure (32%) and continuous positive airway pressure (28%). Cuff-leak tests are seldom performed (1.4%), predominantly in cases of intubation for upper-airway obstruction (92%). Postextubation respiratory support with high-flow nasal oxygen or non-invasive ventilation is used at least as often with therapeutic (43%/13%) rather than preventive (35%/4%) of facilitative intent (29%/3%). Delirium screening (87%) and reconsidering sedation (84%) are frequently assessed in case of weaning failure. Regular use of closed-loop ventilation is reported in a minority of ICUs throughout the process of ventilator liberation (3-9%). 

Conclusions:

Various aspects of ventilator liberation practices show only limited alignment with existing guidelines. The results of this survey pinpoint areas to prioritise in guideline and practice improvement.

Original languageEnglish
Article numbere002868
JournalBMJ Open Respiratory Research
Volume12
Issue number1
DOIs
Publication statusPublished - 21 Jul 2025

Bibliographical note

Publisher Copyright:
© 2025 BMJ Publishing Group. All rights reserved.

Fingerprint

Dive into the research topics of 'Liberation from invasive mechanical ventilation: A nationwide survey among intensive care units in the Netherlands'. Together they form a unique fingerprint.

Cite this