Lobar Distribution of Cerebral Microbleeds The Rotterdam Scan Study

DJ Mesker, Marielle Poels, Arfan Ikram, Meike Vernooij, Bert Hofman, Henri Vrooman, Aad van der Lugt, Monique Breteler

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Objective: To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds. Design: Population-based, cross-sectional analysis. Setting: The Rotterdam Scan Study. Participants: A total of 198 persons (age range, 61-95 years) with lobar microbleeds. Main Outcome Measures: Distribution of microbleeds over different lobes. Results: We found that lobar cerebral microbleeds occurred significantly more often in the temporallobe, a region known to be more affected in cerebral amyloid angiopathy. Conclusion: This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.
Original languageUndefined/Unknown
Pages (from-to)656-659
Number of pages4
JournalArchives of Neurology
Issue number5
Publication statusPublished - 2011

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