Lobar Distribution of Cerebral Microbleeds The Rotterdam Scan Study

DJ Mesker; Marielle Poels; Arfan Ikram; Meike Vernooij; Bert Hofman; Henri Vrooman; Aad van der Lugt; Monique Breteler

doi:10.1001/archneurol.2011.93

Lobar Distribution of Cerebral Microbleeds The Rotterdam Scan Study

DJ Mesker
, Marielle Poels
, Arfan Ikram
, Meike Vernooij
, Bert Hofman
, Henri Vrooman
, Aad van der Lugt
, Monique Breteler

Research output: Contribution to journal › Article › Academic › peer-review

68 Citations (Scopus)

Abstract

Objective: To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds. Design: Population-based, cross-sectional analysis. Setting: The Rotterdam Scan Study. Participants: A total of 198 persons (age range, 61-95 years) with lobar microbleeds. Main Outcome Measures: Distribution of microbleeds over different lobes. Results: We found that lobar cerebral microbleeds occurred significantly more often in the temporallobe, a region known to be more affected in cerebral amyloid angiopathy. Conclusion: This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.

Original language	Undefined/Unknown
Pages (from-to)	656-659
Number of pages	4
Journal	Archives of Neurology
Volume	68
Issue number	5
DOIs	https://doi.org/10.1001/archneurol.2011.93
Publication status	Published - 2011

Research programs

EMC COEUR-09
EMC NIHES-01-64-01
EMC NIHES-03-30-01
EMC NIHES-03-30-03

Access to Document

10.1001/archneurol.2011.93

http://hdl.handle.net/1765/25802

Cite this

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title = "Lobar Distribution of Cerebral Microbleeds The Rotterdam Scan Study",

abstract = "Objective: To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds. Design: Population-based, cross-sectional analysis. Setting: The Rotterdam Scan Study. Participants: A total of 198 persons (age range, 61-95 years) with lobar microbleeds. Main Outcome Measures: Distribution of microbleeds over different lobes. Results: We found that lobar cerebral microbleeds occurred significantly more often in the temporallobe, a region known to be more affected in cerebral amyloid angiopathy. Conclusion: This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.",

author = "DJ Mesker and Marielle Poels and Arfan Ikram and Meike Vernooij and Bert Hofman and Henri Vrooman and \{van der Lugt\}, Aad and Monique Breteler",

year = "2011",

doi = "10.1001/archneurol.2011.93",

language = "Undefined/Unknown",

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journal = "Archives of Neurology",

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T1 - Lobar Distribution of Cerebral Microbleeds The Rotterdam Scan Study

AU - Mesker, DJ

AU - Poels, Marielle

AU - Ikram, Arfan

AU - Vernooij, Meike

AU - Hofman, Bert

AU - Vrooman, Henri

AU - van der Lugt, Aad

AU - Breteler, Monique

PY - 2011

Y1 - 2011

N2 - Objective: To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds. Design: Population-based, cross-sectional analysis. Setting: The Rotterdam Scan Study. Participants: A total of 198 persons (age range, 61-95 years) with lobar microbleeds. Main Outcome Measures: Distribution of microbleeds over different lobes. Results: We found that lobar cerebral microbleeds occurred significantly more often in the temporallobe, a region known to be more affected in cerebral amyloid angiopathy. Conclusion: This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.

AB - Objective: To investigate the distribution of lobar microbleeds over the different lobes, taking into account lobar volume and clustering effects of multiple microbleeds. Design: Population-based, cross-sectional analysis. Setting: The Rotterdam Scan Study. Participants: A total of 198 persons (age range, 61-95 years) with lobar microbleeds. Main Outcome Measures: Distribution of microbleeds over different lobes. Results: We found that lobar cerebral microbleeds occurred significantly more often in the temporallobe, a region known to be more affected in cerebral amyloid angiopathy. Conclusion: This study corroborates the presumed association of lobar microbleeds with cerebral amyloid angiopathy.

U2 - 10.1001/archneurol.2011.93

DO - 10.1001/archneurol.2011.93

M3 - Article

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VL - 68

SP - 656

EP - 659

JO - Archives of Neurology

JF - Archives of Neurology

IS - 5

ER -