Long-term outcome after statin treatment in routine clinical practice: results from a prospective PCI cohort study

Jannet Eindhoven, Yoshinobu Onuma, Rohit Oemrawsingh, Joost Daemen, JWI van Nierop, Peter de Jaegere, Eric Boersma, PWJC (Patrick) Serruys, Ron van Domburg

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Aims: We aim to investigate the association between different types of statins, in particular simvastatin and atorvastatin, and long-term mortality after percutaneous coronary intervention (PCI). Methods and results: Between 2000 and 2005, a prospective cohort was constituted of 5,647 patients who underwent PCI. Type and doses of statin use were collected after the PCI procedure. Survival status was obtained from municipal civil registries. The primary endpoint was all-cause mortality. Secondary endpoints were cardiac and cancer mortality. Median follow-up was 5.0 years (range three to nine years). During follow-up 738 patients (13.1%) died. In total, 4,970 patients (88%) were on statin Conclusions: In patients undergoing PCI the use of statins is associated with reduced mortality during prolonged follow-up. Patients using atorvastatin had a 23% lower mortality than those using simvastatin.
Original languageUndefined/Unknown
Pages (from-to)1420-1427
Number of pages8
Issue number12
Publication statusPublished - 2012

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  • EMC COEUR-09

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