Long-term prognostic value of exercise technetium-99m tetrofosmin myocardial perfusion single-photon emission computed tomography

Henk-Jan Boiten, Jors Van der Sijde, Pauline Ruitinga, R. Valkema, Marcel Geleijnse, E.J.G. Sijbrands, Ron van Domburg, Arend Schinkel

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Abstract

Exercise Tc-99m-tetrofosmin single-photon emission computed tomography (SPECT) is a useful tool for short- and medium-term risk stratifications. Currently, the long-term prognostic application of this technique has not been evaluated. Exercise Tc-99m-tetrofosmin was performed in 655 consecutive patients. Ten patients who underwent revascularization < 60 days after nuclear testing were excluded from the analysis. The present data are based on 638 patients with complete follow-up. An abnormal SPECT study was defined as the presence of fixed and/or reversible perfusion defects. End points were cardiac death, nonfatal infarction, and late coronary revascularization. A total of 344 (54%) patients had an abnormal SPECT study. Perfu Exercise Tc-99m-tetrofosmin myocardial perfusion SPECT has an incremental long-term prognostic value over clinical and stress test parameters for the prediction of major adverse cardiac events.
Original languageUndefined/Unknown
Pages (from-to)907-913
Number of pages7
JournalJournal of Nuclear Cardiology
Volume19
Issue number5
DOIs
Publication statusPublished - 2012

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