TY - JOUR
T1 - Long-term restoration of bowel continuity after rectal cancer resection and the influence of surgical technique
T2 - A nationwide cross-sectional study
AU - Hazen, Sanne Marije J.A.
AU - van Geffen, Eline G.M.
AU - The Dutch Snapshot Research Group
AU - Sluckin, Tania C.
AU - Beets, Geerard L.
AU - Belgers, Henricus J.
AU - Borstlap, Wernard A.A.
AU - Consten, Esther C.J.
AU - Dekker, Jan Willem T.
AU - Hompes, Roel
AU - Tuynman, Jurriaan B.
AU - van Westreenen, Henderik L.
AU - de Wilt, Johannes H.W.
AU - Tanis, Pieter J.
AU - Kusters, Miranda
AU - van Aalten, Susanna M.
AU - Antonisse, Imogeen E.
AU - Boerma, Evert Jan G.
AU - ten Cate, David W.G.
AU - van den Braak, Coebergh
AU - Curutchet, Sam
AU - Dekker, Emmelie N.
AU - Demirkiran, Ahmet
AU - van Egdom, Laurentine S.E.
AU - El-Massoudi, Youssef
AU - van Elderen, Saskia
AU - van Gils, Renza
AU - van den Hoek, Sjoerd
AU - Hoff, Christiaan
AU - Imani, Farshad
AU - van Koeverden, Sebastiaan
AU - Kok, Sylvia
AU - Koster, Ingrid M.
AU - Kroese, Leonard F.
AU - Muller, Karin
AU - Musters, Gijsbert D.
AU - Noordman, Bo J.
AU - Olthof, Pim B.
AU - Oosterling, Steven J.
AU - van Rees, Jan M.
AU - Roosen, Lodewijk
AU - Rothbarth, Joost
AU - Spillenaar-Bilgen, Ernst J.
AU - van der Valk, Maxime J.M.
AU - Vanhooymissen, Inge J.S.
AU - Velema, Laura A.
AU - Verdaasdonk, Emiel G.G.
AU - Verhagen, Tim
AU - Vermaas, Maarten
AU - de Vries, Marianne
AU - van Westerveld, Paul P.
AU - Zheng, Kang J.
N1 - Publisher Copyright:
© 2024 The Authors. Colorectal Disease published by John Wiley & Sons Ltd on behalf of Association of Coloproctology of Great Britain and Ireland.
PY - 2024/6
Y1 - 2024/6
N2 - Aim: Literature on nationwide long-term permanent stoma rates after rectal cancer resection in the minimally invasive era is scarce. The aim of this population-based study was to provide more insight into the permanent stoma rate with interhospital variability (IHV) depending on surgical technique, with pelvic sepsis, unplanned reinterventions and readmissions as secondary outcomes. Method: Patients who underwent open or minimally invasive resection of rectal cancer (lower border below the sigmoid take-off) in 67 Dutch centres in 2016 were included in this cross-sectional cohort study. Results: Among 2530 patients, 1470 underwent a restorative resection (58%), 356 a Hartmann's procedure (14%, IHV 0%–42%) and 704 an abdominoperineal resection (28%, IHV 3%–60%). Median follow-up was 51 months. The overall permanent stoma rate at last follow-up was 50% (IHV 13%–79%) and the unintentional permanent stoma rate, permanent stoma after a restorative procedure or an unplanned Hartmann's procedure, was 11% (IHV 0%–29%). A total of 2165 patients (86%) underwent a minimally invasive resection: 1760 conventional (81%), 170 transanal (8%) and 235 robot-assisted (11%). An anastomosis was created in 59%, 80% and 66%, with corresponding unintentional permanent stoma rates of 12%, 24% and 14% (p = 0.001), respectively. When corrected for age, American Society of Anesthesiologists classification, cTNM, distance to the anorectal junction and neoadjuvant (chemo)radiotherapy, the minimally invasive technique was not associated with an unintended permanent stoma (p = 0.071) after a restorative procedure. Conclusion: A remarkable IHV in the permanent stoma rate after rectal cancer resection was found. No beneficial influence of transanal or robot-assisted laparoscopy on the unintentional permanent stoma rate was found, although this might be caused by the surgical learning curve. A reduction in IHV and improving preoperative counselling for decision-making for restorative procedures are required.
AB - Aim: Literature on nationwide long-term permanent stoma rates after rectal cancer resection in the minimally invasive era is scarce. The aim of this population-based study was to provide more insight into the permanent stoma rate with interhospital variability (IHV) depending on surgical technique, with pelvic sepsis, unplanned reinterventions and readmissions as secondary outcomes. Method: Patients who underwent open or minimally invasive resection of rectal cancer (lower border below the sigmoid take-off) in 67 Dutch centres in 2016 were included in this cross-sectional cohort study. Results: Among 2530 patients, 1470 underwent a restorative resection (58%), 356 a Hartmann's procedure (14%, IHV 0%–42%) and 704 an abdominoperineal resection (28%, IHV 3%–60%). Median follow-up was 51 months. The overall permanent stoma rate at last follow-up was 50% (IHV 13%–79%) and the unintentional permanent stoma rate, permanent stoma after a restorative procedure or an unplanned Hartmann's procedure, was 11% (IHV 0%–29%). A total of 2165 patients (86%) underwent a minimally invasive resection: 1760 conventional (81%), 170 transanal (8%) and 235 robot-assisted (11%). An anastomosis was created in 59%, 80% and 66%, with corresponding unintentional permanent stoma rates of 12%, 24% and 14% (p = 0.001), respectively. When corrected for age, American Society of Anesthesiologists classification, cTNM, distance to the anorectal junction and neoadjuvant (chemo)radiotherapy, the minimally invasive technique was not associated with an unintended permanent stoma (p = 0.071) after a restorative procedure. Conclusion: A remarkable IHV in the permanent stoma rate after rectal cancer resection was found. No beneficial influence of transanal or robot-assisted laparoscopy on the unintentional permanent stoma rate was found, although this might be caused by the surgical learning curve. A reduction in IHV and improving preoperative counselling for decision-making for restorative procedures are required.
UR - http://www.scopus.com/inward/record.url?scp=85192190664&partnerID=8YFLogxK
U2 - 10.1111/codi.17015
DO - 10.1111/codi.17015
M3 - Article
C2 - 38706109
AN - SCOPUS:85192190664
SN - 1462-8910
VL - 26
SP - 1153
EP - 1165
JO - Colorectal Disease
JF - Colorectal Disease
IS - 6
ER -
