Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome

Sergio Martinez Hoyer; Y Deng; J Parker; J Jiang; A Mo; TR Docking; N Gharaee; J Li; P Umlandt; M Fuller; M Jadersten; A Kulasekararaj; L Malcovati; AF List; E Hellstrom-Lindberg; U Platzbecker; A Karsan

doi:10.1038/s41556-020-0497-9

Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome

Sergio Martinez Hoyer
, Y Deng
, J Parker
, J Jiang
, A Mo
, TR Docking
, N Gharaee
, J Li
, P Umlandt
, M Fuller
, M Jadersten
, A Kulasekararaj
, L Malcovati
, AF List
, E Hellstrom-Lindberg
, U Platzbecker
, A Karsan

Hematology

Research output: Contribution to journal › Article › Academic › peer-review

40 Citations (Scopus)

Original language	English
Pages (from-to)	526-533
Number of pages	8
Journal	Nature Cell Biology
Volume	22
Issue number	5
DOIs	https://doi.org/10.1038/s41556-020-0497-9
Publication status	Published - 2020

Research programs

EMC OR-01

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10.1038/s41556-020-0497-9

Cite this

Martinez Hoyer, S., Deng, Y., Parker, J., Jiang, J., Mo, A., Docking, TR., Gharaee, N., Li, J., Umlandt, P., Fuller, M., Jadersten, M., Kulasekararaj, A., Malcovati, L., List, AF., Hellstrom-Lindberg, E., Platzbecker, U., & Karsan, A. (2020). Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome. Nature Cell Biology, 22(5), 526-533. https://doi.org/10.1038/s41556-020-0497-9

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Martinez Hoyer, S, Deng, Y, Parker, J, Jiang, J, Mo, A, Docking, TR, Gharaee, N, Li, J, Umlandt, P, Fuller, M, Jadersten, M, Kulasekararaj, A, Malcovati, L, List, AF, Hellstrom-Lindberg, E, Platzbecker, U & Karsan, A 2020, 'Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome', Nature Cell Biology, vol. 22, no. 5, pp. 526-533. https://doi.org/10.1038/s41556-020-0497-9

TY - JOUR

T1 - Loss of lenalidomide-induced megakaryocytic differentiation leads to therapy resistance in del(5q) myelodysplastic syndrome

AU - Martinez Hoyer, Sergio

AU - Deng, Y

AU - Parker, J

AU - Jiang, J

AU - Mo, A

AU - Docking, TR

AU - Gharaee, N

AU - Li, J

AU - Umlandt, P

AU - Fuller, M

AU - Jadersten, M

AU - Kulasekararaj, A

AU - Malcovati, L

AU - List, AF

AU - Hellstrom-Lindberg, E

AU - Platzbecker, U

AU - Karsan, A

PY - 2020

Y1 - 2020

U2 - 10.1038/s41556-020-0497-9

DO - 10.1038/s41556-020-0497-9

M3 - Article

C2 - 32251398

SN - 1465-7392

VL - 22

SP - 526

EP - 533

JO - Nature Cell Biology

JF - Nature Cell Biology

IS - 5

ER -