TY - JOUR
T1 - Magnetic Resonance Imaging–Based Delineation of Organs at Risk in the Head and Neck Region
AU - Paczona, Viktor R.
AU - Capala, Marta E.
AU - Deák-Karancsi, Borbála
AU - Borzási, Emőke
AU - Együd, Zsófia
AU - Végváry, Zoltán
AU - Kelemen, Gyöngyi
AU - Kószó, Renáta
AU - Ruskó, László
AU - Ferenczi, Lehel
AU - Verduijn, Gerda M.
AU - Petit, Steven F.
AU - Oláh, Judit
AU - Cserháti, Adrienne
AU - Wiesinger, Florian
AU - Hideghéty, Katalin
N1 - Sources of support: This research is part of the Deep MR-only Radiation Therapy activity (project numbers 19037, 20648, and 210995) that has received funding from EIT Health. EIT Health is supported by the European Institute of Innovation and Technology, a body of the European Union that receives support from the Horizon 2020 Research and innovation program.
Publisher Copyright: © 2022
PY - 2023/3/1
Y1 - 2023/3/1
N2 - Purpose: The aim of this article is to establish a comprehensive contouring guideline for treatment planning using only magnetic resonance images through an up-to-date set of organs at risk (OARs), recommended organ boundaries, and relevant suggestions for the magnetic resonance imaging (MRI)–based delineation of OARs in the head and neck (H&N) region. Methods and Materials: After a detailed review of the literature, MRI data were collected from the H&N region of healthy volunteers. OARs were delineated in the axial, coronal, and sagittal planes on T2-weighted sequences. Every contour defined was revised by 4 radiation oncologists and subsequently by 2 independent senior experts (H&N radiation oncologist and radiologist). After revision, the final structures were presented to the consortium partners. Results: A definitive consensus was reached after multi-institutional review. On that basis, we provided a detailed anatomic and functional description and specific MRI characteristics of the OARs. Conclusions: In the era of precision radiation therapy, the need for well-built, straightforward contouring guidelines is on the rise. Precise, uniform, delineation-based, automated OAR segmentation on MRI may lead to increased accuracy in terms of organ boundaries and analysis of dose-dependent sequelae for an adequate definition of normal tissue complication probability.
AB - Purpose: The aim of this article is to establish a comprehensive contouring guideline for treatment planning using only magnetic resonance images through an up-to-date set of organs at risk (OARs), recommended organ boundaries, and relevant suggestions for the magnetic resonance imaging (MRI)–based delineation of OARs in the head and neck (H&N) region. Methods and Materials: After a detailed review of the literature, MRI data were collected from the H&N region of healthy volunteers. OARs were delineated in the axial, coronal, and sagittal planes on T2-weighted sequences. Every contour defined was revised by 4 radiation oncologists and subsequently by 2 independent senior experts (H&N radiation oncologist and radiologist). After revision, the final structures were presented to the consortium partners. Results: A definitive consensus was reached after multi-institutional review. On that basis, we provided a detailed anatomic and functional description and specific MRI characteristics of the OARs. Conclusions: In the era of precision radiation therapy, the need for well-built, straightforward contouring guidelines is on the rise. Precise, uniform, delineation-based, automated OAR segmentation on MRI may lead to increased accuracy in terms of organ boundaries and analysis of dose-dependent sequelae for an adequate definition of normal tissue complication probability.
UR - http://www.scopus.com/inward/record.url?scp=85145046350&partnerID=8YFLogxK
U2 - 10.1016/j.adro.2022.101042
DO - 10.1016/j.adro.2022.101042
M3 - Review article
C2 - 36636382
AN - SCOPUS:85145046350
SN - 2452-1094
VL - 8
JO - Advances in Radiation Oncology
JF - Advances in Radiation Oncology
IS - 2
M1 - 101042
ER -