Management of ALL in adults: 2024 ELN recommendations from a European expert panel

Nicola Gökbuget*, Nicolas Boissel, Sabina Chiaretti, Hervé Dombret, Michael Doubek, Adele Fielding, Robin Foà, Sebastian Giebel, Dieter Hoelzer, Mathilde Hunault, David I. Marks, Giovanni Martinelli, Oliver Ottmann, Anita Rijneveld, Philippe Rousselot, Josep Ribera, Renato Bassan

*Corresponding author for this work

Research output: Contribution to journalComment/Letter to the editorAcademicpeer-review

21 Citations (Scopus)

Abstract

Experts from the European Leukemia Net (ELN) working group for adult acute lymphoblastic leukemia have identified an unmet need for guidance regarding management of adult acute lymphoblastic leukemia (ALL) from diagnosis to aftercare. The group has previously summarized their recommendations regarding diagnostic approaches, prognostic factors, and assessment of ALL. The current recommendation summarizes clinical management. It covers treatment approaches, including the use of new immunotherapies, application of minimal residual disease for treatment decisions, management of specific subgroups, and challenging treatment situations as well as late effects and supportive care. The recommendation provides guidance for physicians caring for adult patients with ALL which has to be complemented by regional expertise preferably provided by national academic study groups.

Original languageEnglish
Pages (from-to)1903-1930
Number of pages28
JournalBlood
Volume143
Issue number19
DOIs
Publication statusPublished - 9 May 2024

Bibliographical note

Publisher Copyright:
© 2024 American Society of Hematology

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