Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: lessons learned from first clinical trials

MISOT Study Group; Marcella Franquesa; Martin J Hoogduijn; Marlies E Reinders; Elke Eggenhofer; Anja U Engela; Fane K Mensah; Joan Torras; Antonello Pileggi; Cees van Kooten; Bernard Mahon; Oliver Detry; Felix C Popp; Volker Benseler; Federica Casiraghi; Christian Johnson; Janis Ancans; Barbara Fillenberg; Olga delaRosa; Josep M Aran; Marieke Roemeling-van Rhijn; Jef Pinxteren; Norberto Perico; Eliana Gotti; Bruno Christ; James Reading; Martino Introna; Robert Deans; Murat Shagidulin; Ramon Farré; Alessandro Rambaldi; Albert Sanchez-Fueyo; Natasha Obermajer; Andrey Pulin; Frank J M F Dor; Isabel Portero-Sanchez; Carla C Baan; Ton J Rabelink; Giuseppe Remuzzi; Michiel G H Betjes; Marc H Dahlke; Josep M Grinyó

doi:10.1097/TP.0b013e318298f9fa

Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: lessons learned from first clinical trials

MISOT Study Group, Marcella Franquesa^*, Martin J Hoogduijn, Marlies E Reinders, Elke Eggenhofer, Anja U Engela, Fane K Mensah, Joan Torras, Antonello Pileggi, Cees van Kooten, Bernard Mahon, Oliver Detry, Felix C Popp, Volker Benseler, Federica Casiraghi, Christian Johnson, Janis Ancans, Barbara Fillenberg, Olga delaRosa, Josep M AranMarieke Roemeling-van Rhijn, Jef Pinxteren, Norberto Perico, Eliana Gotti, Bruno Christ, James Reading, Martino Introna, Robert Deans, Murat Shagidulin, Ramon Farré, Alessandro Rambaldi, Albert Sanchez-Fueyo, Natasha Obermajer, Andrey Pulin, Frank J M F Dor, Isabel Portero-Sanchez, Carla C Baan, Ton J Rabelink, Giuseppe Remuzzi, Michiel G H Betjes, Marc H Dahlke, Josep M Grinyó

^*Corresponding author for this work

Research output: Contribution to journal › Article › Academic › peer-review

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Abstract

The Fourth Expert Meeting of the Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Consortium took place in Barcelona on October 19 and 20, 2012. This meeting focused on the translation of preclinical data into early clinical settings. This position paper highlights the main topics explored on the safety and efficacy of mesenchymal stem cells as a therapeutic agent in solid organ transplantation and emphasizes the issues (proper timing, concomitant immunossupression, source and immunogenicity of mesenchymal stem cells, and oncogenicity) that have been addressed and will be followed up by the MiSOT Consortium in future studies.

Original language	English
Pages (from-to)	234-238
Number of pages	5
Journal	Transplantation
Volume	96
Issue number	3
DOIs	https://doi.org/10.1097/TP.0b013e318298f9fa
Publication status	Published - 15 Aug 2013

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10.1097/TP.0b013e318298f9fa

http://hdl.handle.net/1765/67375

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MISOT Study Group, Franquesa, M., Hoogduijn, M. J., Reinders, M. E., Eggenhofer, E., Engela, A. U., Mensah, F. K., Torras, J., Pileggi, A., van Kooten, C., Mahon, B., Detry, O., Popp, F. C., Benseler, V., Casiraghi, F., Johnson, C., Ancans, J., Fillenberg, B., delaRosa, O., ... Grinyó, J. M. (2013). Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: lessons learned from first clinical trials. Transplantation, 96(3), 234-238. https://doi.org/10.1097/TP.0b013e318298f9fa

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title = "Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: lessons learned from first clinical trials",

abstract = "The Fourth Expert Meeting of the Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Consortium took place in Barcelona on October 19 and 20, 2012. This meeting focused on the translation of preclinical data into early clinical settings. This position paper highlights the main topics explored on the safety and efficacy of mesenchymal stem cells as a therapeutic agent in solid organ transplantation and emphasizes the issues (proper timing, concomitant immunossupression, source and immunogenicity of mesenchymal stem cells, and oncogenicity) that have been addressed and will be followed up by the MiSOT Consortium in future studies.",

author = "{MISOT Study Group} and Marcella Franquesa and Hoogduijn, {Martin J} and Reinders, {Marlies E} and Elke Eggenhofer and Engela, {Anja U} and Mensah, {Fane K} and Joan Torras and Antonello Pileggi and {van Kooten}, Cees and Bernard Mahon and Oliver Detry and Popp, {Felix C} and Volker Benseler and Federica Casiraghi and Christian Johnson and Janis Ancans and Barbara Fillenberg and Olga delaRosa and Aran, {Josep M} and {Roemeling-van Rhijn}, Marieke and Jef Pinxteren and Norberto Perico and Eliana Gotti and Bruno Christ and James Reading and Martino Introna and Robert Deans and Murat Shagidulin and Ramon Farr{\'e} and Alessandro Rambaldi and Albert Sanchez-Fueyo and Natasha Obermajer and Andrey Pulin and Dor, {Frank J M F} and Isabel Portero-Sanchez and Baan, {Carla C} and Rabelink, {Ton J} and Giuseppe Remuzzi and Betjes, {Michiel G H} and Dahlke, {Marc H} and Griny{\'o}, {Josep M}",

year = "2013",

month = aug,

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doi = "10.1097/TP.0b013e318298f9fa",

language = "English",

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MISOT Study Group, Franquesa, M, Hoogduijn, MJ , Reinders, ME, Eggenhofer, E, Engela, AU, Mensah, FK, Torras, J, Pileggi, A, van Kooten, C, Mahon, B, Detry, O, Popp, FC, Benseler, V, Casiraghi, F, Johnson, C, Ancans, J, Fillenberg, B, delaRosa, O, Aran, JM, Roemeling-van Rhijn, M, Pinxteren, J, Perico, N, Gotti, E, Christ, B, Reading, J, Introna, M, Deans, R, Shagidulin, M, Farré, R, Rambaldi, A, Sanchez-Fueyo, A, Obermajer, N, Pulin, A, Dor, FJMF, Portero-Sanchez, I, Baan, CC, Rabelink, TJ, Remuzzi, G, Betjes, MGH, Dahlke, MH & Grinyó, JM 2013, 'Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: lessons learned from first clinical trials', Transplantation, vol. 96, no. 3, pp. 234-238. https://doi.org/10.1097/TP.0b013e318298f9fa

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T1 - Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting

T2 - lessons learned from first clinical trials

AU - MISOT Study Group

AU - Franquesa, Marcella

AU - Hoogduijn, Martin J

AU - Reinders, Marlies E

AU - Eggenhofer, Elke

AU - Engela, Anja U

AU - Mensah, Fane K

AU - Torras, Joan

AU - Pileggi, Antonello

AU - van Kooten, Cees

AU - Mahon, Bernard

AU - Detry, Oliver

AU - Popp, Felix C

AU - Benseler, Volker

AU - Casiraghi, Federica

AU - Johnson, Christian

AU - Ancans, Janis

AU - Fillenberg, Barbara

AU - delaRosa, Olga

AU - Aran, Josep M

AU - Roemeling-van Rhijn, Marieke

AU - Pinxteren, Jef

AU - Perico, Norberto

AU - Gotti, Eliana

AU - Christ, Bruno

AU - Reading, James

AU - Introna, Martino

AU - Deans, Robert

AU - Shagidulin, Murat

AU - Farré, Ramon

AU - Rambaldi, Alessandro

AU - Sanchez-Fueyo, Albert

AU - Obermajer, Natasha

AU - Pulin, Andrey

AU - Dor, Frank J M F

AU - Portero-Sanchez, Isabel

AU - Baan, Carla C

AU - Rabelink, Ton J

AU - Remuzzi, Giuseppe

AU - Betjes, Michiel G H

AU - Dahlke, Marc H

AU - Grinyó, Josep M

PY - 2013/8/15

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N2 - The Fourth Expert Meeting of the Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Consortium took place in Barcelona on October 19 and 20, 2012. This meeting focused on the translation of preclinical data into early clinical settings. This position paper highlights the main topics explored on the safety and efficacy of mesenchymal stem cells as a therapeutic agent in solid organ transplantation and emphasizes the issues (proper timing, concomitant immunossupression, source and immunogenicity of mesenchymal stem cells, and oncogenicity) that have been addressed and will be followed up by the MiSOT Consortium in future studies.

AB - The Fourth Expert Meeting of the Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Consortium took place in Barcelona on October 19 and 20, 2012. This meeting focused on the translation of preclinical data into early clinical settings. This position paper highlights the main topics explored on the safety and efficacy of mesenchymal stem cells as a therapeutic agent in solid organ transplantation and emphasizes the issues (proper timing, concomitant immunossupression, source and immunogenicity of mesenchymal stem cells, and oncogenicity) that have been addressed and will be followed up by the MiSOT Consortium in future studies.

U2 - 10.1097/TP.0b013e318298f9fa

DO - 10.1097/TP.0b013e318298f9fa

M3 - Article

C2 - 23759879

SN - 0041-1337

VL - 96

SP - 234

EP - 238

JO - Transplantation

JF - Transplantation

IS - 3

ER -

Mesenchymal Stem Cells in Solid Organ Transplantation (MiSOT) Fourth Meeting: lessons learned from first clinical trials

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