Mesenchymal Stromal Cell-Based Therapy (Editorial)

Dina Mönch; Marlies E.J. Reinders; Martin J. Hoogduijn; Marc Hendrik Dahlke

doi:10.3390/cells12040559

Mesenchymal Stromal Cell-Based Therapy (Editorial)

Dina Mönch, Marlies E.J. Reinders, Martin J. Hoogduijn, Marc Hendrik Dahlke^*

^*Corresponding author for this work

Internal Medicine

Research output: Contribution to journal › Editorial › Academic › peer-review

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22 Downloads (Pure)

Abstract

The use of mesenchymal stromal cells (MSCs) for clinical application is intensively investigated for a variety of areas, such as bone repair, haematological and autoimmune diseases, and solid organ transplantation. Moreover, increasing insights into their mechanism of actions revealed a lively (paracrine) interaction between MSCs and recipient (immune) cells and identified novel mediators such as extracellular vesicles (EVs). Both paracrine signals and EVs have been shown to play a role in the effects of MSCs and may potentially complement MSC-based therapies or represent therapeutic alternatives. This Special Issue of Cells is devoted to the many aspects of MSC-based therapy and includes original data papers and reviews on preclinical models, clinical studies, as well as MSC manufacturing protocols. [...]

Original language	English
Article number	559
Journal	Cells
Volume	12
Issue number	4
DOIs	https://doi.org/10.3390/cells12040559
Publication status	Published - 3 Feb 2023

Bibliographical note

Funding Information: M.H.D. and D.M. are supported by the Robert Bosch Stiftung, Stuttgart.

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abstract = "The use of mesenchymal stromal cells (MSCs) for clinical application is intensively investigated for a variety of areas, such as bone repair, haematological and autoimmune diseases, and solid organ transplantation. Moreover, increasing insights into their mechanism of actions revealed a lively (paracrine) interaction between MSCs and recipient (immune) cells and identified novel mediators such as extracellular vesicles (EVs). Both paracrine signals and EVs have been shown to play a role in the effects of MSCs and may potentially complement MSC-based therapies or represent therapeutic alternatives. This Special Issue of Cells is devoted to the many aspects of MSC-based therapy and includes original data papers and reviews on preclinical models, clinical studies, as well as MSC manufacturing protocols. [...]",

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AU - Dahlke, Marc Hendrik

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Mesenchymal Stromal Cell-Based Therapy (Editorial)

Abstract

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