Metacognitive therapy versus exposure and response prevention for obsessive-compulsive disorder: study protocol for a randomized controlled trial

Kim Melchior; Ingmar Franken; Mathijs Deen; Colin van der Heiden

doi:10.1186/s13063-019-3381-9

Metacognitive therapy versus exposure and response prevention for obsessive-compulsive disorder: study protocol for a randomized controlled trial

Kim Melchior
, Ingmar Franken
, Mathijs Deen
, Colin van der Heiden

Parnassia Psychiatric Institute & Leiden University

Research output: Contribution to journal › Article › Academic › peer-review

15 Citations (Scopus)

38 Downloads (Pure)

Abstract

BACKGROUND: The recommended psychological treatment of choice for obsessive-compulsive disorder (OCD) is exposure with response prevention (ERP). However, recovery rates are relatively modest, so better treatments are needed. This superiority study aims to explore the relative efficacy of metacognitive therapy (MCT), a new form of cognitive therapy based on the metacognitive model of OCD.

DESIGN AND METHOD: In a randomized controlled trial, we will compare MCT with ERP. One hundred patients diagnosed with OCD will be recruited in an outpatient mental health center in Rotterdam (the Netherlands). The primary outcome measure is OCD severity, measured by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS). Data are assessed at baseline, after treatment, and at 6 and 30 months follow-up.

DISCUSSION: By comparing MCT with ERP we hope to provide an indication whether MCT is efficacious in the treatment of OCD and, if so, whether it has the potential to be more efficacious than the current "gold standard" psychological treatment for OCD, ERP.

TRIAL REGISTRATION: Dutch Trial Register, NTR4855 . Registered on 21 October 2014.

Original language	English
Article number	277
Journal	Trials
Volume	20
Issue number	1
DOIs	https://doi.org/10.1186/s13063-019-3381-9
Publication status	Published - 20 May 2019

Bibliographical note

Publisher Copyright:
© 2019 The Author(s).

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Metacognitive therapy versus exposure and response prevention for obsessive-compulsive disorder: study protocol for a randomized controlled trial
Melchior, K. (Creator), Franken, I. (Creator), Deen, M. (Creator) & van der Heiden, C. (Contributor), 2019
DOI: 10.6084/m9.figshare.c.4511249.v1, https://springernature.figshare.com/collections/Metacognitive_therapy_versus_exposure_and_response_prevention_for_obsessive-compulsive_disorder_study_protocol_for_a_randomized_controlled_trial/4511249/1 and one more link, https://springernature.figshare.com/collections/Metacognitive_therapy_versus_exposure_and_response_prevention_for_obsessive-compulsive_disorder_study_protocol_for_a_randomized_controlled_trial/4511249 (show fewer)
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title = "Metacognitive therapy versus exposure and response prevention for obsessive-compulsive disorder: study protocol for a randomized controlled trial",

abstract = "BACKGROUND: The recommended psychological treatment of choice for obsessive-compulsive disorder (OCD) is exposure with response prevention (ERP). However, recovery rates are relatively modest, so better treatments are needed. This superiority study aims to explore the relative efficacy of metacognitive therapy (MCT), a new form of cognitive therapy based on the metacognitive model of OCD.DESIGN AND METHOD: In a randomized controlled trial, we will compare MCT with ERP. One hundred patients diagnosed with OCD will be recruited in an outpatient mental health center in Rotterdam (the Netherlands). The primary outcome measure is OCD severity, measured by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS). Data are assessed at baseline, after treatment, and at 6 and 30 months follow-up.DISCUSSION: By comparing MCT with ERP we hope to provide an indication whether MCT is efficacious in the treatment of OCD and, if so, whether it has the potential to be more efficacious than the current {"}gold standard{"} psychological treatment for OCD, ERP.TRIAL REGISTRATION: Dutch Trial Register, NTR4855 . Registered on 21 October 2014.",

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N2 - BACKGROUND: The recommended psychological treatment of choice for obsessive-compulsive disorder (OCD) is exposure with response prevention (ERP). However, recovery rates are relatively modest, so better treatments are needed. This superiority study aims to explore the relative efficacy of metacognitive therapy (MCT), a new form of cognitive therapy based on the metacognitive model of OCD.DESIGN AND METHOD: In a randomized controlled trial, we will compare MCT with ERP. One hundred patients diagnosed with OCD will be recruited in an outpatient mental health center in Rotterdam (the Netherlands). The primary outcome measure is OCD severity, measured by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS). Data are assessed at baseline, after treatment, and at 6 and 30 months follow-up.DISCUSSION: By comparing MCT with ERP we hope to provide an indication whether MCT is efficacious in the treatment of OCD and, if so, whether it has the potential to be more efficacious than the current "gold standard" psychological treatment for OCD, ERP.TRIAL REGISTRATION: Dutch Trial Register, NTR4855 . Registered on 21 October 2014.

AB - BACKGROUND: The recommended psychological treatment of choice for obsessive-compulsive disorder (OCD) is exposure with response prevention (ERP). However, recovery rates are relatively modest, so better treatments are needed. This superiority study aims to explore the relative efficacy of metacognitive therapy (MCT), a new form of cognitive therapy based on the metacognitive model of OCD.DESIGN AND METHOD: In a randomized controlled trial, we will compare MCT with ERP. One hundred patients diagnosed with OCD will be recruited in an outpatient mental health center in Rotterdam (the Netherlands). The primary outcome measure is OCD severity, measured by the Yale-Brown Obsessive Compulsive Scale (Y-BOCS). Data are assessed at baseline, after treatment, and at 6 and 30 months follow-up.DISCUSSION: By comparing MCT with ERP we hope to provide an indication whether MCT is efficacious in the treatment of OCD and, if so, whether it has the potential to be more efficacious than the current "gold standard" psychological treatment for OCD, ERP.TRIAL REGISTRATION: Dutch Trial Register, NTR4855 . Registered on 21 October 2014.

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Metacognitive therapy versus exposure and response prevention for obsessive-compulsive disorder: study protocol for a randomized controlled trial

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Metacognitive therapy versus exposure and response prevention for obsessive-compulsive disorder: study protocol for a randomized controlled trial

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