Metric properties of advanced imaging methods in osteoarthritis of the hand: a systematic review

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12 Citations (Scopus)

Abstract

Objective To assess the value of advanced imaging techniques in the detection of hand osteoarthritis (OA) and hand OA progression. Methods PubMed/Medline and Embase were searched until April 2012 for studies on imaging of hand OA that presented quantitative data on validity, reliability or responsiveness. Articles presenting only data on conventional radiography (CR) were excluded. Methodological quality was assessed by the Quality Assessment of Diagnostic Accuracy Studies (QUADAS) checklist for validity, the Quality Appraisal of Reliability Studies (QAREL) for reliability and the COSMIN (COnsensus-based Standards for the s Results Of 627 citations, 25 studies on ultrasonography (US), MRI or scintigraphy were included. No studies on CT, positron emission tomography or single photon emission CT met our eligibility criteria. Validity was generally assessed against healthy controls, CR or clinical examination. Overall, US and MRI detected more disease than CR and found significant differences between patients and healthy controls. Scintigraphy detected fewer pathological joints than CR. Intra-and inter-reader reliabil Conclusions MRI and US seem to be the most promising candidates for early detection of hand OA and for future use in clinical trials. However, further research is needed to improve scoring methods, to compare US with MRI, to confirm reliability of MRI and to further determine the responsiveness of US and MRI.
Original languageUndefined/Unknown
Pages (from-to)365-375
Number of pages11
JournalAnnals of the Rheumatic Diseases
Volume73
Issue number2
DOIs
Publication statusPublished - 2014

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