Mismatch repair and homeologous recombination

Khek chian Tham; Roland Kanaar; Joyce Lebbink

doi:10.1016/j.dnarep.2015.11.010

Mismatch repair and homeologous recombination

Khek chian Tham, Roland Kanaar, Joyce Lebbink

Research output: Contribution to journal › Article › Academic

68 Citations (Scopus)

Abstract

DNA mismatch repair influences the outcome of recombination events between diverging DNA sequences. Here we discuss how mismatch repair proteins are active in different homologous recombination subpathways and specific reaction steps, resulting in differential modulation of these recombination events, with a focus on the mechanism of heteroduplex rejection during the inhibition of recombination between slightly diverged (homeologous) DNA sequences. (C) 2015 Elsevier B.V. All rights reserved.

Original language	Undefined/Unknown
Pages (from-to)	75-83
Number of pages	9
Journal	DNA Repair
Volume	38
DOIs	https://doi.org/10.1016/j.dnarep.2015.11.010
Publication status	Published - 2016

Research programs

EMC MGC-01-12-03
EMC MM-03-32-04

Access to Document

10.1016/j.dnarep.2015.11.010

http://hdl.handle.net/1765/79561

Cite this

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title = "Mismatch repair and homeologous recombination",

abstract = "DNA mismatch repair influences the outcome of recombination events between diverging DNA sequences. Here we discuss how mismatch repair proteins are active in different homologous recombination subpathways and specific reaction steps, resulting in differential modulation of these recombination events, with a focus on the mechanism of heteroduplex rejection during the inhibition of recombination between slightly diverged (homeologous) DNA sequences. (C) 2015 Elsevier B.V. All rights reserved.",

author = "Tham, \{Khek chian\} and Roland Kanaar and Joyce Lebbink",

year = "2016",

doi = "10.1016/j.dnarep.2015.11.010",

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T1 - Mismatch repair and homeologous recombination

AU - Tham, Khek chian

AU - Kanaar, Roland

AU - Lebbink, Joyce

PY - 2016

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N2 - DNA mismatch repair influences the outcome of recombination events between diverging DNA sequences. Here we discuss how mismatch repair proteins are active in different homologous recombination subpathways and specific reaction steps, resulting in differential modulation of these recombination events, with a focus on the mechanism of heteroduplex rejection during the inhibition of recombination between slightly diverged (homeologous) DNA sequences. (C) 2015 Elsevier B.V. All rights reserved.

AB - DNA mismatch repair influences the outcome of recombination events between diverging DNA sequences. Here we discuss how mismatch repair proteins are active in different homologous recombination subpathways and specific reaction steps, resulting in differential modulation of these recombination events, with a focus on the mechanism of heteroduplex rejection during the inhibition of recombination between slightly diverged (homeologous) DNA sequences. (C) 2015 Elsevier B.V. All rights reserved.

U2 - 10.1016/j.dnarep.2015.11.010

DO - 10.1016/j.dnarep.2015.11.010

M3 - Article

C2 - 26739221

SN - 1568-7864

VL - 38

SP - 75

EP - 83

JO - DNA Repair

JF - DNA Repair

ER -