Monochorionic diamniotic twin pregnancies: natural history and risk stratification

Liesbeth Lewi; Leonardo Gucciardo; Tim Van Mieghem; Philippe de Koninck; Veronika Beck; Helga Medek; Dominique Van Schoubroeck; Roland Devlieger; Luc De Catte; Jan Deprest

doi:10.1159/000313300

Monochorionic diamniotic twin pregnancies: natural history and risk stratification

Liesbeth Lewi, Leonardo Gucciardo, Tim Van Mieghem, Philippe de Koninck, Veronika Beck, Helga Medek, Dominique Van Schoubroeck, Roland Devlieger, Luc De Catte, Jan Deprest

Research output: Contribution to journal › Review article › Academic › peer-review

165 Citations (Scopus)

Abstract

About 30% of monochorionic twin pregnancies are complicated by twin-to-twin transfusion syndrome (TTTS), isolated discordant growth, twin anemia-polycythemia sequence, congenital defects or intrauterine demise. About 15% will be eligible for invasive fetal therapy, either fetoscopic laser treatment for TTTS or fetoscopic or ultrasound-guided umbilical cord coagulation for a severe congenital defect in one twin or severe discordant growth with imminent demise of the growth-restricted twin. Ultrasound examination in the first and early second trimester can differentiate the monochorionic twins at high risk for adverse outcome from those likely to be uneventful, which may be useful for patient counselling and planning of care.

Original language	English
Pages (from-to)	121-33
Number of pages	13
Journal	Fetal Diagnosis and Therapy
Volume	27
Issue number	3
DOIs	https://doi.org/10.1159/000313300
Publication status	Published - 2010
Externally published	Yes

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10.1159/000313300

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title = "Monochorionic diamniotic twin pregnancies: natural history and risk stratification",

abstract = "About 30% of monochorionic twin pregnancies are complicated by twin-to-twin transfusion syndrome (TTTS), isolated discordant growth, twin anemia-polycythemia sequence, congenital defects or intrauterine demise. About 15% will be eligible for invasive fetal therapy, either fetoscopic laser treatment for TTTS or fetoscopic or ultrasound-guided umbilical cord coagulation for a severe congenital defect in one twin or severe discordant growth with imminent demise of the growth-restricted twin. Ultrasound examination in the first and early second trimester can differentiate the monochorionic twins at high risk for adverse outcome from those likely to be uneventful, which may be useful for patient counselling and planning of care.",

author = "Liesbeth Lewi and Leonardo Gucciardo and {Van Mieghem}, Tim and {de Koninck}, Philippe and Veronika Beck and Helga Medek and {Van Schoubroeck}, Dominique and Roland Devlieger and {De Catte}, Luc and Jan Deprest",

year = "2010",

doi = "10.1159/000313300",

language = "English",

volume = "27",

pages = "121--33",

journal = "Fetal Diagnosis and Therapy",

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T1 - Monochorionic diamniotic twin pregnancies

T2 - natural history and risk stratification

AU - Lewi, Liesbeth

AU - Gucciardo, Leonardo

AU - Van Mieghem, Tim

AU - de Koninck, Philippe

AU - Beck, Veronika

AU - Medek, Helga

AU - Van Schoubroeck, Dominique

AU - Devlieger, Roland

AU - De Catte, Luc

AU - Deprest, Jan

PY - 2010

Y1 - 2010

N2 - About 30% of monochorionic twin pregnancies are complicated by twin-to-twin transfusion syndrome (TTTS), isolated discordant growth, twin anemia-polycythemia sequence, congenital defects or intrauterine demise. About 15% will be eligible for invasive fetal therapy, either fetoscopic laser treatment for TTTS or fetoscopic or ultrasound-guided umbilical cord coagulation for a severe congenital defect in one twin or severe discordant growth with imminent demise of the growth-restricted twin. Ultrasound examination in the first and early second trimester can differentiate the monochorionic twins at high risk for adverse outcome from those likely to be uneventful, which may be useful for patient counselling and planning of care.

AB - About 30% of monochorionic twin pregnancies are complicated by twin-to-twin transfusion syndrome (TTTS), isolated discordant growth, twin anemia-polycythemia sequence, congenital defects or intrauterine demise. About 15% will be eligible for invasive fetal therapy, either fetoscopic laser treatment for TTTS or fetoscopic or ultrasound-guided umbilical cord coagulation for a severe congenital defect in one twin or severe discordant growth with imminent demise of the growth-restricted twin. Ultrasound examination in the first and early second trimester can differentiate the monochorionic twins at high risk for adverse outcome from those likely to be uneventful, which may be useful for patient counselling and planning of care.

U2 - 10.1159/000313300

DO - 10.1159/000313300

M3 - Review article

C2 - 20413975

SN - 1015-3837

VL - 27

SP - 121

EP - 133

JO - Fetal Diagnosis and Therapy

JF - Fetal Diagnosis and Therapy

IS - 3

ER -

Monochorionic diamniotic twin pregnancies: natural history and risk stratification

Abstract

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