Moving molecular targeted drug therapy towards personalized medicine: Issues related to clinical trial design

Jaap Verweij; Maja de Jonge; Ferry Eskens; Stefan Sleijfer

doi:10.1016/j.molonc.2012.01.009

Moving molecular targeted drug therapy towards personalized medicine: Issues related to clinical trial design

Jaap Verweij, Maja de Jonge, Ferry Eskens, Stefan Sleijfer

Medical Oncology

Research output: Contribution to journal › Article › Academic

19 Citations (Scopus)

22 Downloads (Pure)

Abstract

With the event of new Molecular targets, clinical trial design requirements to perform these trials are changing. This paper discusses some of the considerations that need to be taken into account when designing a trial, including those trials that assess combinations of targets. (C) 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

Original language	Undefined/Unknown
Pages (from-to)	196-203
Number of pages	8
Journal	Molecular Oncology
Volume	6
Issue number	2
DOIs	https://doi.org/10.1016/j.molonc.2012.01.009
Publication status	Published - 2012

Research programs

EMC MM-03-86-01
EMC MM-03-86-08

Access to Document

10.1016/j.molonc.2012.01.009

Verweij_et_al-2012-Molecular_Oncology.pdfFinal published version, 221 KB

http://hdl.handle.net/1765/70105

Cite this

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abstract = "With the event of new Molecular targets, clinical trial design requirements to perform these trials are changing. This paper discusses some of the considerations that need to be taken into account when designing a trial, including those trials that assess combinations of targets. (C) 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.",

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AB - With the event of new Molecular targets, clinical trial design requirements to perform these trials are changing. This paper discusses some of the considerations that need to be taken into account when designing a trial, including those trials that assess combinations of targets. (C) 2012 Federation of European Biochemical Societies. Published by Elsevier B.V. All rights reserved.

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