Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

L Paternoster; M Standl; J Waage; H Baurecht; M Hotze; DP Strachan; JA Curtin; K Bonnelykke; C Tian; A Takahashi; J Esparza-Gordillo; AC Alves; JP Thyssen; Martijn den Dekker; MA Ferreira; E Altmaier; PMA Sleiman; FL Xiao; JR Gonzalez; I Marenholz; B Kalb; M Pino-Yanes; CJ Xu; L Carstensen; MM Groen-Blokhuis; C Venturini; CE Pennell; SJ Barton; AM Levin; I Curjuric; M Bustamante; E Kreiner-Moller; GA Lockett; J Bacelis; S Bunyavanich; RA Myers; A Matanovic; A Kumar; JY Tung; T Hirota; M Kubo; WL McArdle; AJ Henderson; JP Kemp; J Zheng; GD Smith; F Rueschendorf; A Bauerfeind; MA Lee-Kirsch; A Arnold; G Homuth; CO Schmidt; E Mangold; S Cichon; T Keil; E Rodriguez; A Peters; A Franke; W Lieb; N Novak; R Foelster-Holst; M Horikoshi; J Pekkanen; S Sebert; LL Husemoen; N Grarup; Johan Jongste; Fernando Rivadeneira; Bert Hofman; Vincent Jaddoe; Suzanne Pasmans; Niels Elbert; André Uitterlinden; GB Marks; PJ Thompson; MC Matheson; CF Robertson; JS Ried; Juan Li; XB Zuo; XD Zheng; XY Yin; LD Sun; MA McAleer; GM O'Regan; CMR Fahy; LE Campbell; M Macek; M Kurek; D Hu; C Eng; DS Postma; B Feenstra; F Geller; JJ (Jouke Jan) Hottenga; CM (Christel) Middeldorp; P Hysi; V Bataille; T Spector; CMT Tiesler; E Thiering; B Pahukasahasram; JJ Yang; M Imboden; S Huntsman; N Vilor-Tejedor; CL Relton; R Myhre; W Nystad; A Custovic; ST Weiss; DA Meyers; C Soederhaell; E Melen; C Ober; BA Raby; A Simpson; B Jacobsson; JW Holloway; H Bisgaard; J Sunyer; NM Probst-Hensch; LK Williams; KM Godfrey; CA Wang; DI Boomsma; M Melbye; GH Koppelman; D Jarvis; WHI McLean; AD Irvine; XJ Zhang; H Hakonarson; C Gieger-; EG Burchard; NG Martin; Liesbeth Duijts; A Linneberg; MR Jarvelin; MM Noethen; S Lau; N Huebner; YA van der Lee; M Tamari; DA Hinds; D Glass; SJ Brown; J (Joachim) Heinrich; DM Evans; S Weidinger

doi:10.1038/ng.3424

Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

L Paternoster, M Standl, J Waage, H Baurecht, M Hotze, DP Strachan, JA Curtin, K Bonnelykke, C Tian, A Takahashi, J Esparza-Gordillo, AC Alves, JP Thyssen, Martijn den Dekker, MA Ferreira, E Altmaier, PMA Sleiman, FL Xiao, JR Gonzalez, I MarenholzB Kalb, M Pino-Yanes, CJ Xu, L Carstensen, MM Groen-Blokhuis, C Venturini, CE Pennell, SJ Barton, AM Levin, I Curjuric, M Bustamante, E Kreiner-Moller, GA Lockett, J Bacelis, S Bunyavanich, RA Myers, A Matanovic, A Kumar, JY Tung, T Hirota, M Kubo, WL McArdle, AJ Henderson, JP Kemp, J Zheng, GD Smith, F Rueschendorf, A Bauerfeind, MA Lee-Kirsch, A Arnold, G Homuth, CO Schmidt, E Mangold, S Cichon, T Keil, E Rodriguez, A Peters, A Franke, W Lieb, N Novak, R Foelster-Holst, M Horikoshi, J Pekkanen, S Sebert, LL Husemoen, N Grarup, Johan Jongste, Fernando Rivadeneira, Bert Hofman, Vincent Jaddoe, Suzanne Pasmans, Niels Elbert, André Uitterlinden, GB Marks, PJ Thompson, MC Matheson, CF Robertson, JS Ried, Juan Li, XB Zuo, XD Zheng, XY Yin, LD Sun, MA McAleer, GM O'Regan, CMR Fahy, LE Campbell, M Macek, M Kurek, D Hu, C Eng, DS Postma, B Feenstra, F Geller, JJ (Jouke Jan) Hottenga, CM (Christel) Middeldorp, P Hysi, V Bataille, T Spector, CMT Tiesler, E Thiering, B Pahukasahasram, JJ Yang, M Imboden, S Huntsman, N Vilor-Tejedor, CL Relton, R Myhre, W Nystad, A Custovic, ST Weiss, DA Meyers, C Soederhaell, E Melen, C Ober, BA Raby, A Simpson, B Jacobsson, JW Holloway, H Bisgaard, J Sunyer, NM Probst-Hensch, LK Williams, KM Godfrey, CA Wang, DI Boomsma, M Melbye, GH Koppelman, D Jarvis, WHI McLean, AD Irvine, XJ Zhang, H Hakonarson, C Gieger-, EG Burchard, NG Martin, Liesbeth Duijts, A Linneberg, MR Jarvelin, MM Noethen, S Lau, N Huebner, YA van der Lee, M Tamari, DA Hinds, D Glass, SJ Brown, J (Joachim) Heinrich, DM Evans, S Weidinger

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476 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	1449-+
Journal	Nature Genetics
Volume	47
Issue number	12
DOIs	https://doi.org/10.1038/ng.3424
Publication status	Published - 2015

Research programs

EMC MM-01-39-09-A
EMC MM-03-54-04-A
EMC MM-03-61-05-A
EMC MM-04-54-08-A
EMC OR-01-54-02

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10.1038/ng.3424

Cite this

Paternoster, L., Standl, M., Waage, J., Baurecht, H., Hotze, M., Strachan, DP., Curtin, JA., Bonnelykke, K., Tian, C., Takahashi, A., Esparza-Gordillo, J., Alves, AC., Thyssen, JP., den Dekker, M., Ferreira, MA., Altmaier, E., Sleiman, PMA., Xiao, FL., Gonzalez, JR., ... Weidinger, S. (2015). Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis. Nature Genetics, 47(12), 1449-+. https://doi.org/10.1038/ng.3424

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title = "Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis",

author = "L Paternoster and M Standl and J Waage and H Baurecht and M Hotze and DP Strachan and JA Curtin and K Bonnelykke and C Tian and A Takahashi and J Esparza-Gordillo and AC Alves and JP Thyssen and {den Dekker}, Martijn and MA Ferreira and E Altmaier and PMA Sleiman and FL Xiao and JR Gonzalez and I Marenholz and B Kalb and M Pino-Yanes and CJ Xu and L Carstensen and MM Groen-Blokhuis and C Venturini and CE Pennell and SJ Barton and AM Levin and I Curjuric and M Bustamante and E Kreiner-Moller and GA Lockett and J Bacelis and S Bunyavanich and RA Myers and A Matanovic and A Kumar and JY Tung and T Hirota and M Kubo and WL McArdle and AJ Henderson and JP Kemp and J Zheng and GD Smith and F Rueschendorf and A Bauerfeind and MA Lee-Kirsch and A Arnold and G Homuth and CO Schmidt and E Mangold and S Cichon and T Keil and E Rodriguez and A Peters and A Franke and W Lieb and N Novak and R Foelster-Holst and M Horikoshi and J Pekkanen and S Sebert and LL Husemoen and N Grarup and Johan Jongste and Fernando Rivadeneira and Bert Hofman and Vincent Jaddoe and Suzanne Pasmans and Niels Elbert and Andr{\'e} Uitterlinden and GB Marks and PJ Thompson and MC Matheson and CF Robertson and JS Ried and Juan Li and XB Zuo and XD Zheng and XY Yin and LD Sun and MA McAleer and GM O'Regan and CMR Fahy and LE Campbell and M Macek and M Kurek and D Hu and C Eng and DS Postma and B Feenstra and F Geller and Hottenga, {JJ (Jouke Jan)} and Middeldorp, {CM (Christel)} and P Hysi and V Bataille and T Spector and CMT Tiesler and E Thiering and B Pahukasahasram and JJ Yang and M Imboden and S Huntsman and N Vilor-Tejedor and CL Relton and R Myhre and W Nystad and A Custovic and ST Weiss and DA Meyers and C Soederhaell and E Melen and C Ober and BA Raby and A Simpson and B Jacobsson and JW Holloway and H Bisgaard and J Sunyer and NM Probst-Hensch and LK Williams and KM Godfrey and CA Wang and DI Boomsma and M Melbye and GH Koppelman and D Jarvis and WHI McLean and AD Irvine and XJ Zhang and H Hakonarson and C Gieger- and EG Burchard and NG Martin and Liesbeth Duijts and A Linneberg and MR Jarvelin and MM Noethen and S Lau and N Huebner and {van der Lee}, YA and M Tamari and DA Hinds and D Glass and SJ Brown and Heinrich, {J (Joachim)} and DM Evans and S Weidinger",

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doi = "10.1038/ng.3424",

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volume = "47",

pages = "1449--+",

journal = "Nature Genetics",

issn = "1061-4036",

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Paternoster, L, Standl, M, Waage, J, Baurecht, H, Hotze, M, Strachan, DP, Curtin, JA, Bonnelykke, K, Tian, C, Takahashi, A, Esparza-Gordillo, J, Alves, AC, Thyssen, JP, den Dekker, M, Ferreira, MA, Altmaier, E, Sleiman, PMA, Xiao, FL, Gonzalez, JR, Marenholz, I, Kalb, B, Pino-Yanes, M, Xu, CJ, Carstensen, L, Groen-Blokhuis, MM, Venturini, C, Pennell, CE, Barton, SJ, Levin, AM, Curjuric, I, Bustamante, M, Kreiner-Moller, E, Lockett, GA, Bacelis, J, Bunyavanich, S, Myers, RA, Matanovic, A, Kumar, A, Tung, JY, Hirota, T, Kubo, M, McArdle, WL, Henderson, AJ, Kemp, JP, Zheng, J, Smith, GD, Rueschendorf, F, Bauerfeind, A, Lee-Kirsch, MA, Arnold, A, Homuth, G, Schmidt, CO, Mangold, E, Cichon, S, Keil, T, Rodriguez, E, Peters, A, Franke, A, Lieb, W, Novak, N, Foelster-Holst, R, Horikoshi, M, Pekkanen, J, Sebert, S, Husemoen, LL, Grarup, N, Jongste, J, Rivadeneira, F , Hofman, B , Jaddoe, V , Pasmans, S, Elbert, N, Uitterlinden, A, Marks, GB, Thompson, PJ, Matheson, MC, Robertson, CF, Ried, JS, Li, J, Zuo, XB, Zheng, XD, Yin, XY, Sun, LD, McAleer, MA, O'Regan, GM, Fahy, CMR, Campbell, LE, Macek, M, Kurek, M, Hu, D, Eng, C, Postma, DS, Feenstra, B, Geller, F, Hottenga, JJ, Middeldorp, CM, Hysi, P, Bataille, V, Spector, T, Tiesler, CMT, Thiering, E, Pahukasahasram, B, Yang, JJ, Imboden, M, Huntsman, S, Vilor-Tejedor, N, Relton, CL, Myhre, R, Nystad, W, Custovic, A, Weiss, ST, Meyers, DA, Soederhaell, C, Melen, E, Ober, C, Raby, BA, Simpson, A, Jacobsson, B, Holloway, JW, Bisgaard, H, Sunyer, J, Probst-Hensch, NM, Williams, LK, Godfrey, KM, Wang, CA, Boomsma, DI, Melbye, M, Koppelman, GH, Jarvis, D, McLean, WHI, Irvine, AD, Zhang, XJ, Hakonarson, H, Gieger-, C, Burchard, EG, Martin, NG, Duijts, L, Linneberg, A, Jarvelin, MR, Noethen, MM, Lau, S, Huebner, N, van der Lee, YA, Tamari, M, Hinds, DA, Glass, D, Brown, SJ, Heinrich, J, Evans, DM & Weidinger, S 2015, 'Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis', Nature Genetics, vol. 47, no. 12, pp. 1449-+. https://doi.org/10.1038/ng.3424

TY - JOUR

T1 - Multi-ancestry genome-wide association study of 21,000 cases and 95,000 controls identifies new risk loci for atopic dermatitis

AU - Paternoster, L

AU - Standl, M

AU - Waage, J

AU - Baurecht, H

AU - Hotze, M

AU - Strachan, DP

AU - Curtin, JA

AU - Bonnelykke, K

AU - Tian, C

AU - Takahashi, A

AU - Esparza-Gordillo, J

AU - Alves, AC

AU - Thyssen, JP

AU - den Dekker, Martijn

AU - Ferreira, MA

AU - Altmaier, E

AU - Sleiman, PMA

AU - Xiao, FL

AU - Gonzalez, JR

AU - Marenholz, I

AU - Kalb, B

AU - Pino-Yanes, M

AU - Xu, CJ

AU - Carstensen, L

AU - Groen-Blokhuis, MM

AU - Venturini, C

AU - Pennell, CE

AU - Barton, SJ

AU - Levin, AM

AU - Curjuric, I

AU - Bustamante, M

AU - Kreiner-Moller, E

AU - Lockett, GA

AU - Bacelis, J

AU - Bunyavanich, S

AU - Myers, RA

AU - Matanovic, A

AU - Kumar, A

AU - Tung, JY

AU - Hirota, T

AU - Kubo, M

AU - McArdle, WL

AU - Henderson, AJ

AU - Kemp, JP

AU - Zheng, J

AU - Smith, GD

AU - Rueschendorf, F

AU - Bauerfeind, A

AU - Lee-Kirsch, MA

AU - Arnold, A

AU - Homuth, G

AU - Schmidt, CO

AU - Mangold, E

AU - Cichon, S

AU - Keil, T

AU - Rodriguez, E

AU - Peters, A

AU - Franke, A

AU - Lieb, W

AU - Novak, N

AU - Foelster-Holst, R

AU - Horikoshi, M

AU - Pekkanen, J

AU - Sebert, S

AU - Husemoen, LL

AU - Grarup, N

AU - Jongste, Johan

AU - Rivadeneira, Fernando

AU - Hofman, Bert

AU - Jaddoe, Vincent

AU - Pasmans, Suzanne

AU - Elbert, Niels

AU - Uitterlinden, André

AU - Marks, GB

AU - Thompson, PJ

AU - Matheson, MC

AU - Robertson, CF

AU - Ried, JS

AU - Li, Juan

AU - Zuo, XB

AU - Zheng, XD

AU - Yin, XY

AU - Sun, LD

AU - McAleer, MA

AU - O'Regan, GM

AU - Fahy, CMR

AU - Campbell, LE

AU - Macek, M

AU - Kurek, M

AU - Hu, D

AU - Eng, C

AU - Postma, DS

AU - Feenstra, B

AU - Geller, F

AU - Hottenga, JJ (Jouke Jan)

AU - Middeldorp, CM (Christel)

AU - Hysi, P

AU - Bataille, V

AU - Spector, T

AU - Tiesler, CMT

AU - Thiering, E

AU - Pahukasahasram, B

AU - Yang, JJ

AU - Imboden, M

AU - Huntsman, S

AU - Vilor-Tejedor, N

AU - Relton, CL

AU - Myhre, R

AU - Nystad, W

AU - Custovic, A

AU - Weiss, ST

AU - Meyers, DA

AU - Soederhaell, C

AU - Melen, E

AU - Ober, C

AU - Raby, BA

AU - Simpson, A

AU - Jacobsson, B

AU - Holloway, JW

AU - Bisgaard, H

AU - Sunyer, J

AU - Probst-Hensch, NM

AU - Williams, LK

AU - Godfrey, KM

AU - Wang, CA

AU - Boomsma, DI

AU - Melbye, M

AU - Koppelman, GH

AU - Jarvis, D

AU - McLean, WHI

AU - Irvine, AD

AU - Zhang, XJ

AU - Hakonarson, H

AU - Gieger-, C

AU - Burchard, EG

AU - Martin, NG

AU - Duijts, Liesbeth

AU - Linneberg, A

AU - Jarvelin, MR

AU - Noethen, MM

AU - Lau, S

AU - Huebner, N

AU - van der Lee, YA

AU - Tamari, M

AU - Hinds, DA

AU - Glass, D

AU - Brown, SJ

AU - Heinrich, J (Joachim)

AU - Evans, DM

AU - Weidinger, S

PY - 2015

Y1 - 2015

U2 - 10.1038/ng.3424

DO - 10.1038/ng.3424

M3 - Article

C2 - 26482879

SN - 1061-4036

VL - 47

SP - 1449-+

JO - Nature Genetics

JF - Nature Genetics

IS - 12

ER -