Abstract
The clinical application of diffusion MRI is practically hindered by its long scan time. In this work, we introduce a novel imaging and parameter estimation framework for time-efficient diffusion MRI. To improve the scan efficiency, we propose ADEPT (Accelerated Diffusion EPI with multi-contrast shoTs), in which diffusion contrast settings are allowed to change between shots in a multi-shot EPI acquisition (i.e. intra-scan modulation). The framework simultaneously corrects for artifacts related to shot-to-shot phase inconsistencies in multi-shot imaging by iteratively estimating the phase map parameters along with the diffusion model parameters directly from the acquired intra-scan modulated k-space data. Monte Carlo simulation experiments show the effective estimation of diffusion tensor parameters in multi-shot EPI diffusion imaging.
| Original language | English |
|---|---|
| Pages (from-to) | 3869-3872 |
| Number of pages | 4 |
| Journal | Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS |
| Volume | 2021-January |
| DOIs | |
| Publication status | Published - 9 Dec 2021 |
| Event | 43rd Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2021 - Virtual, Online, Mexico Duration: 1 Nov 2021 → 5 Nov 2021 |
Bibliographical note
Funding Information:*This project has received funding from the European Union’s Horizon 2020 research and innovation program under the Marie Sklodowska-Curie grant agreement No 764513. The authors also acknowledge support of the European Space Agency (ESA) and BELSPO Prodex, and the Research Foundation Flanders (FWO Belgium) through project funding G084217N and 12M3116N. 1imec-Vision Lab, Dept. Physics, Univ. Antwerp, Antwerp, Belgium 2BIGR, Erasmus MC, Rotterdam, The Netherlands 3µNEURO Research Centre of Excell., Univ. Antwerp, Antwerp, Belgium
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