Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

F Demenais; P Margaritte-Jeannin; KC Barnes; WOC Cookson; J Altmuller; W Ang; RG Barr; TH Beaty; AB Becker; J Beilby; H Bisgaard; US Bjornsdottir; E Bleecker; K Bonnelykke; DI Boomsma; E Bouzigon; CE Brightling; M Brossard; Guy Brusselle; E Burchard; KM Burkart; A Bush; M Chan-Yeung; KF Chung; AC Alves; JA Curtin; A Custovic; D Daley; Johan Jongste; BE Del-Rio-Navarro; KM Donohue; Liesbeth Duijts; C Eng; JG Eriksson; M Farrall; Y Fedorova; B Feenstra; MA Ferreira; MB Freidin; Z Gajdos; J Gauderman; U Gehring; F Geller; J Genuneit; SA Gharib; F Gilliland; R Granell; PE Graves; DF Gudbjartsson; T Haahtela; SR Heckbert; D Heederik; J Heinrich; M Heliovaara; J Henderson; BE Himes; H Hirose; JN Hirschhorn; Bert Hofman; P Holt; J Hottenga; TJ Hudson; J Hui; M Imboden; V Ivanov; Vincent Jaddoe; A James; C Janson; MR Jarvelin; D Jarvis; G Jones; I Jonsdottir; P Jousilahti; M Kabesch; M Kahonen; DB Kantor; AS Karunas; E Khusnutdinova; GH Koppelman; AL Kozyrskyj; E Kreiner; M Kubo; R Kumar; A Kumar; M Kuokkanen; Lies Lahousse; T Laitinen; C Laprise; M Lathrop; S Lau; YA van der Lee; T Lehtimaki; S Letort; AM Levin; G Li; LM Liang; LR Loehr; SJ London; Daan Loth; A Manichaikul; I Marenholz; FJ Martinez; MC Matheson; RA Mathias; K Matsumoto; H Mbarek; WL McArdle; M Melbye; E Melen; D Meyers; S Michel; H Mohamdi; AW Musk; RA Myers; MAE Nieuwenhuis; E Noguchi; GT O'Connor; LM Ogorodova; CD Palmer; A Palotie; JE Park; CE Pennell; G Pershagen; A Polonikov; DS Postma; N Probst-Hensch; VP Puzyrev; BA Raby; OT Raitakari; A Ramasamy; SS Rich; CF Robertson; I Romieu; MT Salam; V Salomaa; V Schlunssen; R Scott; PA Selivanova; T Sigsgaard; A Simpson; V Siroux; LJ Smith; M Solodilova; M Standl; K Stefansson; DP Strachan; Bruno Stricker; A Takahashi; PJ Thompson; G Thorleifsson; U Thorsteinsdottir; CMT Tiesler; DG Torgerson; T Tsunoda; André Uitterlinden; Ralf Valk; A Vaysse; S Vedantam; A (Andrea) van den Berg; E von Mutius; JM Vonk; J Waage; NJ Wareham; ST Weiss; WB White; M Wickman; E Widen; G Willemsen; LK Williams; IM Wouters; JJ Yang; JH Zhao; MF Moffatt; C Ober; DL Nicolae

doi:10.1038/s41588-017-0014-7

Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

F Demenais
, P Margaritte-Jeannin
, KC Barnes
, WOC Cookson
, J Altmuller
, W Ang
, RG Barr
, TH Beaty
, AB Becker
, J Beilby
, H Bisgaard
, US Bjornsdottir
, E Bleecker
, K Bonnelykke
, DI Boomsma
, E Bouzigon
, CE Brightling
, M Brossard
, Guy Brusselle
, E Burchard

KM Burkart, A Bush, M Chan-Yeung, KF Chung, AC Alves, JA Curtin, A Custovic, D Daley, Johan Jongste, BE Del-Rio-Navarro, KM Donohue, Liesbeth Duijts, C Eng, JG Eriksson, M Farrall, Y Fedorova, B Feenstra, MA Ferreira, MB Freidin, Z Gajdos, J Gauderman, U Gehring, F Geller, J Genuneit, SA Gharib, F Gilliland, R Granell, PE Graves, DF Gudbjartsson, T Haahtela, SR Heckbert, D Heederik, J Heinrich, M Heliovaara, J Henderson, BE Himes, H Hirose, JN Hirschhorn, Bert Hofman, P Holt, J Hottenga, TJ Hudson, J Hui, M Imboden, V Ivanov, Vincent Jaddoe, A James, C Janson, MR Jarvelin, D Jarvis, G Jones, I Jonsdottir, P Jousilahti, M Kabesch, M Kahonen, DB Kantor, AS Karunas, E Khusnutdinova, GH Koppelman, AL Kozyrskyj, E Kreiner, M Kubo, R Kumar, A Kumar, M Kuokkanen, Lies Lahousse, T Laitinen, C Laprise, M Lathrop, S Lau, YA van der Lee, T Lehtimaki, S Letort, AM Levin, G Li, LM Liang, LR Loehr, SJ London, Daan Loth, A Manichaikul, I Marenholz, FJ Martinez, MC Matheson, RA Mathias, K Matsumoto, H Mbarek, WL McArdle, M Melbye, E Melen, D Meyers, S Michel, H Mohamdi, AW Musk, RA Myers, MAE Nieuwenhuis, E Noguchi, GT O'Connor, LM Ogorodova, CD Palmer, A Palotie, JE Park, CE Pennell, G Pershagen, A Polonikov, DS Postma, N Probst-Hensch, VP Puzyrev, BA Raby, OT Raitakari, A Ramasamy, SS Rich, CF Robertson, I Romieu, MT Salam, V Salomaa, V Schlunssen, R Scott, PA Selivanova, T Sigsgaard, A Simpson, V Siroux, LJ Smith, M Solodilova, M Standl, K Stefansson, DP Strachan, Bruno Stricker, A Takahashi, PJ Thompson, G Thorleifsson, U Thorsteinsdottir, CMT Tiesler, DG Torgerson, T Tsunoda, André Uitterlinden, Ralf Valk, A Vaysse, S Vedantam, A (Andrea) van den Berg, E von Mutius, JM Vonk, J Waage, NJ Wareham, ST Weiss, WB White, M Wickman, E Widen, G Willemsen, LK Williams, IM Wouters, JJ Yang, JH Zhao, MF Moffatt, C Ober, DL Nicolae

Research output: Contribution to journal › Article › Academic › peer-review

438 Citations (Scopus)

Original language	Undefined/Unknown
Pages (from-to)	42-+
Journal	Nature Genetics
Volume	50
Issue number	1
DOIs	https://doi.org/10.1038/s41588-017-0014-7
Publication status	Published - 2018

Research programs

EMC MM-01-39-09-A
EMC MM-03-54-04-A
EMC MM-04-42-02
EMC MM-04-54-08-A
EMC OR-01-54-02

Access to Document

10.1038/s41588-017-0014-7

http://hdl.handle.net/1765/103735

Cite this

Demenais, F., Margaritte-Jeannin, P., Barnes, KC., Cookson, WOC., Altmuller, J., Ang, W., Barr, RG., Beaty, TH., Becker, AB., Beilby, J., Bisgaard, H., Bjornsdottir, US., Bleecker, E., Bonnelykke, K., Boomsma, DI., Bouzigon, E., Brightling, CE., Brossard, M., Brusselle, G., ... Nicolae, DL. (2018). Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks. Nature Genetics, 50(1), 42-+. https://doi.org/10.1038/s41588-017-0014-7

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doi = "10.1038/s41588-017-0014-7",

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volume = "50",

pages = "42--+",

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Demenais, F, Margaritte-Jeannin, P, Barnes, KC, Cookson, WOC, Altmuller, J, Ang, W, Barr, RG, Beaty, TH, Becker, AB, Beilby, J, Bisgaard, H, Bjornsdottir, US, Bleecker, E, Bonnelykke, K, Boomsma, DI, Bouzigon, E, Brightling, CE, Brossard, M, Brusselle, G, Burchard, E, Burkart, KM, Bush, A, Chan-Yeung, M, Chung, KF, Alves, AC, Curtin, JA, Custovic, A, Daley, D, Jongste, J, Del-Rio-Navarro, BE, Donohue, KM, Duijts, L, Eng, C, Eriksson, JG, Farrall, M, Fedorova, Y, Feenstra, B, Ferreira, MA, Freidin, MB, Gajdos, Z, Gauderman, J, Gehring, U, Geller, F, Genuneit, J, Gharib, SA, Gilliland, F, Granell, R, Graves, PE, Gudbjartsson, DF, Haahtela, T, Heckbert, SR, Heederik, D, Heinrich, J, Heliovaara, M, Henderson, J, Himes, BE, Hirose, H, Hirschhorn, JN, Hofman, B, Holt, P, Hottenga, J, Hudson, TJ, Hui, J, Imboden, M, Ivanov, V, Jaddoe, V, James, A, Janson, C, Jarvelin, MR, Jarvis, D, Jones, G, Jonsdottir, I, Jousilahti, P, Kabesch, M, Kahonen, M, Kantor, DB, Karunas, AS, Khusnutdinova, E, Koppelman, GH, Kozyrskyj, AL, Kreiner, E, Kubo, M, Kumar, R, Kumar, A, Kuokkanen, M, Lahousse, L, Laitinen, T, Laprise, C, Lathrop, M, Lau, S, van der Lee, YA, Lehtimaki, T, Letort, S, Levin, AM, Li, G, Liang, LM, Loehr, LR, London, SJ, Loth, D, Manichaikul, A, Marenholz, I, Martinez, FJ, Matheson, MC, Mathias, RA, Matsumoto, K, Mbarek, H, McArdle, WL, Melbye, M, Melen, E, Meyers, D, Michel, S, Mohamdi, H, Musk, AW, Myers, RA, Nieuwenhuis, MAE, Noguchi, E, O'Connor, GT, Ogorodova, LM, Palmer, CD, Palotie, A, Park, JE, Pennell, CE, Pershagen, G, Polonikov, A, Postma, DS, Probst-Hensch, N, Puzyrev, VP, Raby, BA, Raitakari, OT, Ramasamy, A, Rich, SS, Robertson, CF, Romieu, I, Salam, MT, Salomaa, V, Schlunssen, V, Scott, R, Selivanova, PA, Sigsgaard, T, Simpson, A, Siroux, V, Smith, LJ, Solodilova, M, Standl, M, Stefansson, K, Strachan, DP, Stricker, B, Takahashi, A, Thompson, PJ, Thorleifsson, G, Thorsteinsdottir, U, Tiesler, CMT, Torgerson, DG, Tsunoda, T, Uitterlinden, A, Valk, R, Vaysse, A, Vedantam, S, van den Berg, A, von Mutius, E, Vonk, JM, Waage, J, Wareham, NJ, Weiss, ST, White, WB, Wickman, M, Widen, E, Willemsen, G, Williams, LK, Wouters, IM, Yang, JJ, Zhao, JH, Moffatt, MF, Ober, C & Nicolae, DL 2018, 'Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks', Nature Genetics, vol. 50, no. 1, pp. 42-+. https://doi.org/10.1038/s41588-017-0014-7

TY - JOUR

T1 - Multiancestry association study identifies new asthma risk loci that colocalize with immune-cell enhancer marks

AU - Demenais, F

AU - Margaritte-Jeannin, P

AU - Barnes, KC

AU - Cookson, WOC

AU - Altmuller, J

AU - Ang, W

AU - Barr, RG

AU - Beaty, TH

AU - Becker, AB

AU - Beilby, J

AU - Bisgaard, H

AU - Bjornsdottir, US

AU - Bleecker, E

AU - Bonnelykke, K

AU - Boomsma, DI

AU - Bouzigon, E

AU - Brightling, CE

AU - Brossard, M

AU - Brusselle, Guy

AU - Burchard, E

AU - Burkart, KM

AU - Bush, A

AU - Chan-Yeung, M

AU - Chung, KF

AU - Alves, AC

AU - Curtin, JA

AU - Custovic, A

AU - Daley, D

AU - Jongste, Johan

AU - Del-Rio-Navarro, BE

AU - Donohue, KM

AU - Duijts, Liesbeth

AU - Eng, C

AU - Eriksson, JG

AU - Farrall, M

AU - Fedorova, Y

AU - Feenstra, B

AU - Ferreira, MA

AU - Freidin, MB

AU - Gajdos, Z

AU - Gauderman, J

AU - Gehring, U

AU - Geller, F

AU - Genuneit, J

AU - Gharib, SA

AU - Gilliland, F

AU - Granell, R

AU - Graves, PE

AU - Gudbjartsson, DF

AU - Haahtela, T

AU - Heckbert, SR

AU - Heederik, D

AU - Heinrich, J

AU - Heliovaara, M

AU - Henderson, J

AU - Himes, BE

AU - Hirose, H

AU - Hirschhorn, JN

AU - Hofman, Bert

AU - Holt, P

AU - Hottenga, J

AU - Hudson, TJ

AU - Hui, J

AU - Imboden, M

AU - Ivanov, V

AU - Jaddoe, Vincent

AU - James, A

AU - Janson, C

AU - Jarvelin, MR

AU - Jarvis, D

AU - Jones, G

AU - Jonsdottir, I

AU - Jousilahti, P

AU - Kabesch, M

AU - Kahonen, M

AU - Kantor, DB

AU - Karunas, AS

AU - Khusnutdinova, E

AU - Koppelman, GH

AU - Kozyrskyj, AL

AU - Kreiner, E

AU - Kubo, M

AU - Kumar, R

AU - Kumar, A

AU - Kuokkanen, M

AU - Lahousse, Lies

AU - Laitinen, T

AU - Laprise, C

AU - Lathrop, M

AU - Lau, S

AU - van der Lee, YA

AU - Lehtimaki, T

AU - Letort, S

AU - Levin, AM

AU - Li, G

AU - Liang, LM

AU - Loehr, LR

AU - London, SJ

AU - Loth, Daan

AU - Manichaikul, A

AU - Marenholz, I

AU - Martinez, FJ

AU - Matheson, MC

AU - Mathias, RA

AU - Matsumoto, K

AU - Mbarek, H

AU - McArdle, WL

AU - Melbye, M

AU - Melen, E

AU - Meyers, D

AU - Michel, S

AU - Mohamdi, H

AU - Musk, AW

AU - Myers, RA

AU - Nieuwenhuis, MAE

AU - Noguchi, E

AU - O'Connor, GT

AU - Ogorodova, LM

AU - Palmer, CD

AU - Palotie, A

AU - Park, JE

AU - Pennell, CE

AU - Pershagen, G

AU - Polonikov, A

AU - Postma, DS

AU - Probst-Hensch, N

AU - Puzyrev, VP

AU - Raby, BA

AU - Raitakari, OT

AU - Ramasamy, A

AU - Rich, SS

AU - Robertson, CF

AU - Romieu, I

AU - Salam, MT

AU - Salomaa, V

AU - Schlunssen, V

AU - Scott, R

AU - Selivanova, PA

AU - Sigsgaard, T

AU - Simpson, A

AU - Siroux, V

AU - Smith, LJ

AU - Solodilova, M

AU - Standl, M

AU - Stefansson, K

AU - Strachan, DP

AU - Stricker, Bruno

AU - Takahashi, A

AU - Thompson, PJ

AU - Thorleifsson, G

AU - Thorsteinsdottir, U

AU - Tiesler, CMT

AU - Torgerson, DG

AU - Tsunoda, T

AU - Uitterlinden, André

AU - Valk, Ralf

AU - Vaysse, A

AU - Vedantam, S

AU - van den Berg, A (Andrea)

AU - von Mutius, E

AU - Vonk, JM

AU - Waage, J

AU - Wareham, NJ

AU - Weiss, ST

AU - White, WB

AU - Wickman, M

AU - Widen, E

AU - Willemsen, G

AU - Williams, LK

AU - Wouters, IM

AU - Yang, JJ

AU - Zhao, JH

AU - Moffatt, MF

AU - Ober, C

AU - Nicolae, DL

PY - 2018

Y1 - 2018

U2 - 10.1038/s41588-017-0014-7

DO - 10.1038/s41588-017-0014-7

M3 - Article

SN - 1061-4036

VL - 50

SP - 42-+

JO - Nature Genetics

JF - Nature Genetics

IS - 1

ER -