Multimodality treatment for esophageal squamous cell carcinoma

Xing Gao

Multimodality treatment for esophageal squamous cell carcinoma

Xing Gao

Surgery

Research output: Types of Thesis › Doctoral Thesis › Internal

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Abstract

This thesis aims to optimize multimodality treatments for locally advanced esophageal squamous cell carcinoma (ESCC), specifically in East-Asia, recognizing that ESCC may differ in biology and response to treatment in different parts of the world. Part I of the thesis introduces the subtype ESCC and its characteristics from different geographical perspectives followed by an exposition of the differences between ESCC in eastern and western worlds. Part II optimizes trimodal therapy of ESCC in Taiwan, as a representative region of East-Asia. Finally, in Part III, the accuracy of liquid biopsies in identifying patients who may not need surgery after trimodal therapy is assessed..

Original language	English
Awarding Institution	Erasmus University Rotterdam
Supervisors/Advisors	Wijnhoven, Bas, Supervisor van Lanschot, Jan, Co-supervisor Chao, YK, Co-supervisor, External person
Award date	30 Aug 2023
Place of Publication	Rotterdam
Publication status	Published - 30 Aug 2023

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final dissertation Gao, XingFinal published version, 28.3 MB
embargo version Gao, XingOther version, 8.72 MB

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title = "Multimodality treatment for esophageal squamous cell carcinoma",

abstract = "This thesis aims to optimize multimodality treatments for locally advanced esophageal squamous cell carcinoma (ESCC), specifically in East-Asia, recognizing that ESCC may differ in biology and response to treatment in different parts of the world. Part I of the thesis introduces the subtype ESCC and its characteristics from different geographical perspectives followed by an exposition of the differences between ESCC in eastern and western worlds. Part II optimizes trimodal therapy of ESCC in Taiwan, as a representative region of East-Asia. Finally, in Part III, the accuracy of liquid biopsies in identifying patients who may not need surgery after trimodal therapy is assessed..",

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N2 - This thesis aims to optimize multimodality treatments for locally advanced esophageal squamous cell carcinoma (ESCC), specifically in East-Asia, recognizing that ESCC may differ in biology and response to treatment in different parts of the world. Part I of the thesis introduces the subtype ESCC and its characteristics from different geographical perspectives followed by an exposition of the differences between ESCC in eastern and western worlds. Part II optimizes trimodal therapy of ESCC in Taiwan, as a representative region of East-Asia. Finally, in Part III, the accuracy of liquid biopsies in identifying patients who may not need surgery after trimodal therapy is assessed..

AB - This thesis aims to optimize multimodality treatments for locally advanced esophageal squamous cell carcinoma (ESCC), specifically in East-Asia, recognizing that ESCC may differ in biology and response to treatment in different parts of the world. Part I of the thesis introduces the subtype ESCC and its characteristics from different geographical perspectives followed by an exposition of the differences between ESCC in eastern and western worlds. Part II optimizes trimodal therapy of ESCC in Taiwan, as a representative region of East-Asia. Finally, in Part III, the accuracy of liquid biopsies in identifying patients who may not need surgery after trimodal therapy is assessed..

M3 - Doctoral Thesis

CY - Rotterdam

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Multimodality treatment for esophageal squamous cell carcinoma

Abstract

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