Mutation and drug-specific intracellular accumulation of EGFR predict clinical responses to tyrosine kinase inhibitors

Maurice de Wit; Ya Gao; Darlene Mercieca; Iris de Heer; Bart Valkenburg; Martin van Royen; Joachim Aerts; Peter Sillevis Smitt; Pim French

doi:10.1016/j.ebiom.2020.102796

Mutation and drug-specific intracellular accumulation of EGFR predict clinical responses to tyrosine kinase inhibitors

Maurice de Wit, Ya Gao, Darlene Mercieca, Iris de Heer, Bart Valkenburg, Martin van Royen, Joachim Aerts, Peter Sillevis Smitt, Pim French

Research output: Contribution to journal › Article › Academic › peer-review

9 Citations (Scopus)

16 Downloads (Pure)

Original language	English
Article number	102796
Journal	EBioMedicine
Volume	56
DOIs	https://doi.org/10.1016/j.ebiom.2020.102796
Publication status	Published - 2020

Research programs

EMC MM-03-24-01
EMC MM-03-44-06
EMC MM-04-42-02

Access to Document

10.1016/j.ebiom.2020.102796

Repub_127725_O-A.pdfFinal published version, 4.4 MB

http://hdl.handle.net/1765/127725

Cite this

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title = "Mutation and drug-specific intracellular accumulation of EGFR predict clinical responses to tyrosine kinase inhibitors",

author = "\{de Wit\}, Maurice and Ya Gao and Darlene Mercieca and \{de Heer\}, Iris and Bart Valkenburg and \{van Royen\}, Martin and Joachim Aerts and \{Sillevis Smitt\}, Peter and Pim French",

year = "2020",

doi = "10.1016/j.ebiom.2020.102796",

language = "English",

volume = "56",

journal = "EBioMedicine",

issn = "2352-3964",

publisher = "Elsevier",

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T1 - Mutation and drug-specific intracellular accumulation of EGFR predict clinical responses to tyrosine kinase inhibitors

AU - de Wit, Maurice

AU - Gao, Ya

AU - Mercieca, Darlene

AU - de Heer, Iris

AU - Valkenburg, Bart

AU - van Royen, Martin

AU - Aerts, Joachim

AU - Sillevis Smitt, Peter

AU - French, Pim

PY - 2020

Y1 - 2020

U2 - 10.1016/j.ebiom.2020.102796

DO - 10.1016/j.ebiom.2020.102796

M3 - Article

C2 - 32512509

SN - 2352-3964

VL - 56

JO - EBioMedicine

JF - EBioMedicine

M1 - 102796

ER -