Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

CN Toepfer; AC Garfinkel; G Venturini; H Wakimoto; G Repetti; L Alamo; A Sharma; R Agarwal; JF Ewoldt; P Cloonan; J Letendre; M Lun; I Olivotto; S Colan; E Ashley; D Jacoby; Michelle Michels; CS Redwood; HC Watkins; S M Day; JF Staples; R Padrón; A Chopra; CY Ho; CS Chen; AC Pereira; JG Seidman; CE Seidman

doi:10.1161/CIRCULATIONAHA.119.042339

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

CN Toepfer, AC Garfinkel, G Venturini, H Wakimoto, G Repetti, L Alamo, A Sharma, R Agarwal, JF Ewoldt, P Cloonan, J Letendre, M Lun, I Olivotto, S Colan, E Ashley, D Jacoby, Michelle Michels, CS Redwood, HC Watkins, S M DayJF Staples, R Padrón, A Chopra, CY Ho, CS Chen, AC Pereira, JG Seidman, CE Seidman

Cardiology

Research output: Contribution to journal › Article › Academic › peer-review

196 Citations (Scopus)

22 Downloads (Pure)

Original language	English
Pages (from-to)	828-842
Number of pages	15
Journal	Circulation
Volume	141
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.119.042339
Publication status	Published - 2020

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10.1161/CIRCULATIONAHA.119.042339

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Toepfer, CN., Garfinkel, AC., Venturini, G., Wakimoto, H., Repetti, G., Alamo, L., Sharma, A., Agarwal, R., Ewoldt, JF., Cloonan, P., Letendre, J., Lun, M., Olivotto, I., Colan, S., Ashley, E., Jacoby, D., Michels, M., Redwood, CS., Watkins, HC., ... Seidman, CE. (2020). Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy. Circulation, 141, 828-842. https://doi.org/10.1161/CIRCULATIONAHA.119.042339

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author = "CN Toepfer and AC Garfinkel and G Venturini and H Wakimoto and G Repetti and L Alamo and A Sharma and R Agarwal and JF Ewoldt and P Cloonan and J Letendre and M Lun and I Olivotto and S Colan and E Ashley and D Jacoby and Michelle Michels and CS Redwood and HC Watkins and Day, {S M} and JF Staples and R Padr{\'o}n and A Chopra and CY Ho and CS Chen and AC Pereira and JG Seidman and CE Seidman",

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doi = "10.1161/CIRCULATIONAHA.119.042339",

language = "English",

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pages = "828--842",

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Toepfer, CN, Garfinkel, AC, Venturini, G, Wakimoto, H, Repetti, G, Alamo, L, Sharma, A, Agarwal, R, Ewoldt, JF, Cloonan, P, Letendre, J, Lun, M, Olivotto, I, Colan, S, Ashley, E, Jacoby, D, Michels, M, Redwood, CS, Watkins, HC, Day, SM, Staples, JF, Padrón, R, Chopra, A, Ho, CY, Chen, CS, Pereira, AC, Seidman, JG & Seidman, CE 2020, 'Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy', Circulation, vol. 141, pp. 828-842. https://doi.org/10.1161/CIRCULATIONAHA.119.042339

TY - JOUR

T1 - Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

AU - Toepfer, CN

AU - Garfinkel, AC

AU - Venturini, G

AU - Wakimoto, H

AU - Repetti, G

AU - Alamo, L

AU - Sharma, A

AU - Agarwal, R

AU - Ewoldt, JF

AU - Cloonan, P

AU - Letendre, J

AU - Lun, M

AU - Olivotto, I

AU - Colan, S

AU - Ashley, E

AU - Jacoby, D

AU - Michels, Michelle

AU - Redwood, CS

AU - Watkins, HC

AU - Day, S M

AU - Staples, JF

AU - Padrón, R

AU - Chopra, A

AU - Ho, CY

AU - Chen, CS

AU - Pereira, AC

AU - Seidman, JG

AU - Seidman, CE

PY - 2020

Y1 - 2020

U2 - 10.1161/CIRCULATIONAHA.119.042339

DO - 10.1161/CIRCULATIONAHA.119.042339

M3 - Article

C2 - 31983222

SN - 0009-7322

VL - 141

SP - 828

EP - 842

JO - Circulation

JF - Circulation

ER -