Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

CN Toepfer; AC Garfinkel; G Venturini; H Wakimoto; G Repetti; L Alamo; A Sharma; R Agarwal; JF Ewoldt; P Cloonan; J Letendre; M Lun; I Olivotto; S Colan; E Ashley; D Jacoby; Michelle Michels; CS Redwood; HC Watkins; S M Day; JF Staples; R Padrón; A Chopra; CY Ho; CS Chen; AC Pereira; JG Seidman; CE Seidman

doi:10.1161/CIRCULATIONAHA.119.042339

Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

CN Toepfer
, AC Garfinkel
, G Venturini
, H Wakimoto
, G Repetti
, L Alamo
, A Sharma
, R Agarwal
, JF Ewoldt
, P Cloonan
, J Letendre
, M Lun
, I Olivotto
, S Colan
, E Ashley
, D Jacoby
, Michelle Michels
, CS Redwood
, HC Watkins
, S M Day

JF Staples, R Padrón, A Chopra, CY Ho, CS Chen, AC Pereira, JG Seidman, CE Seidman

Cardiology

Research output: Contribution to journal › Article › Academic › peer-review

245 Citations (Scopus)

51 Downloads (Pure)

Original language	English
Pages (from-to)	828-842
Number of pages	15
Journal	Circulation
Volume	141
DOIs	https://doi.org/10.1161/CIRCULATIONAHA.119.042339
Publication status	Published - 2020

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EMC COEUR-09

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10.1161/CIRCULATIONAHA.119.042339

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Cite this

Toepfer, CN., Garfinkel, AC., Venturini, G., Wakimoto, H., Repetti, G., Alamo, L., Sharma, A., Agarwal, R., Ewoldt, JF., Cloonan, P., Letendre, J., Lun, M., Olivotto, I., Colan, S., Ashley, E., Jacoby, D., Michels, M., Redwood, CS., Watkins, HC., ... Seidman, CE. (2020). Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy. Circulation, 141, 828-842. https://doi.org/10.1161/CIRCULATIONAHA.119.042339

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doi = "10.1161/CIRCULATIONAHA.119.042339",

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Toepfer, CN, Garfinkel, AC, Venturini, G, Wakimoto, H, Repetti, G, Alamo, L, Sharma, A, Agarwal, R, Ewoldt, JF, Cloonan, P, Letendre, J, Lun, M, Olivotto, I, Colan, S, Ashley, E, Jacoby, D, Michels, M, Redwood, CS, Watkins, HC, Day, SM, Staples, JF, Padrón, R, Chopra, A, Ho, CY, Chen, CS, Pereira, AC, Seidman, JG & Seidman, CE 2020, 'Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy', Circulation, vol. 141, pp. 828-842. https://doi.org/10.1161/CIRCULATIONAHA.119.042339

TY - JOUR

T1 - Myosin Sequestration Regulates Sarcomere Function, Cardiomyocyte Energetics, and Metabolism, Informing the Pathogenesis of Hypertrophic Cardiomyopathy

AU - Toepfer, CN

AU - Garfinkel, AC

AU - Venturini, G

AU - Wakimoto, H

AU - Repetti, G

AU - Alamo, L

AU - Sharma, A

AU - Agarwal, R

AU - Ewoldt, JF

AU - Cloonan, P

AU - Letendre, J

AU - Lun, M

AU - Olivotto, I

AU - Colan, S

AU - Ashley, E

AU - Jacoby, D

AU - Michels, Michelle

AU - Redwood, CS

AU - Watkins, HC

AU - Day, S M

AU - Staples, JF

AU - Padrón, R

AU - Chopra, A

AU - Ho, CY

AU - Chen, CS

AU - Pereira, AC

AU - Seidman, JG

AU - Seidman, CE

PY - 2020

Y1 - 2020

U2 - 10.1161/CIRCULATIONAHA.119.042339

DO - 10.1161/CIRCULATIONAHA.119.042339

M3 - Article

C2 - 31983222

SN - 0009-7322

VL - 141

SP - 828

EP - 842

JO - Circulation

JF - Circulation

ER -